797694
name: Phosphorylation
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modifier: 734586
is: http://identifiers.org/ec-code/2.7.11.30
product: 734574
is: GO:0030618
kinetic law: 734598
is: GO:0004674
type: Reaction
reversible: false
fast: false

515029
units: metaid_0000037
value: 0.563
type: LocalParameter

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is homolog to: Q13485
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
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in compartment: 797477
name: Smad4_cyt
type: Species

797714
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product: 734621
reactant: 734610
is: GO:0007184
fast: false
reversible: true
name: R-Smad translocation
type: Reaction

797674
in compartment: 797494
constant: false
type: Species
is: C00009
initial concentration: NaN
name: Pi
is: CHEBI:18367
initial amount: 0.0
has only substance units: true
boundary condition: false

797734
kinetic law: 734669
product: 734657
reactant: 734645
is: GO:0006611
fast: false
reversible: true
name: Smad4 translocation
type: Reaction

734562
stoichiometry: 1.0
species: 797514
type: SpeciesReference

797774
kinetic law: 734755
product: 734742
reactant: 734730
is: GO:0007184
fast: false
reversible: false
name: Complex translocation
type: Reaction

734864
stoichiometry: 1.0
species: 797495
type: SpeciesReference

BIOMD0000000112
notes: The model reproduces the temporal evolution of four variables depicted in Fig 2a. The solution is generated for median parameter values as given in Table 3. Result shown was generated by MathSBML. This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2010 The BioModels.net Team. For more information see the terms of use . To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
species: 797674
rule: metaid_0000033
created:
  W3 CDTF: Wed Nov 29 11:35:49 GMT 2006
name: Clarke2006_Smad_signalling
units def: metaid_0000028
units def: metaid_0000027
species: 797574
modified:
  W3 CDTF: Fri Oct 29 14:55:44 BST 2010
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species: 797654
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reaction: 797734
species: 797554
species: 797495
volume units: metaid_0000084
creator:
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    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
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species: 797634
is: MODEL4024559990
species: 797534
parameter: metaid_0000032
parameter: metaid_0000029
occurs in: http://identifiers.org/taxonomy/452646
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reaction: 797694
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reaction: 797754
creator:
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  n:
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reaction: 797814
type: SBMLModel
length unit: length
species: 797594
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515030
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797534
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species: 797574
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797754
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reactant: 734681
name: Complex formation
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reversible: true
product: 734705

797594
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species: 797634
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734478
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797834
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reversible: false
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species: 797614
type: SpeciesReference

797634
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metaid_0000037
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734693
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species: 797554
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797814
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product: 734827
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fast: false
reversible: false
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797514
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metaid_0000030
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797794
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734791
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797614
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797654
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metaid_0003037
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metaid_0002037
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metaid_0000031
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734490
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734657
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797494
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metaid_0000032
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metaid_0000029
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