(Factor value) GENOTYPE/empty vector
type: EFO_0000001
property type: GENOTYPE
property value: empty vector

Fbxo2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.20926970323833
p value: 0.0102001249648636
refers to: Fbxo2
refers to: 1427004_at
t statistic: 8.07683611054058

Igfbp5 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.21349617074413
p value: 0.0348370918806774
refers to: Igfbp5
refers to: 1452114_s_at
t statistic: 5.55590092839642

Crct1
type: EnsemblDatabaseReference

Pdgfra
type: EnsemblDatabaseReference

1435264_at
type: EFO_0005072
part of: A-AFFY-45

Pdgfra
type: EnsemblDatabaseReference

1437718_x_at
type: EFO_0005072
part of: A-AFFY-45

Sfrp1
type: EnsemblDatabaseReference

1450791_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) H_CBX8-b1
type: Assay
has participant: A-AFFY-45

Mest
type: EnsemblDatabaseReference

(Assay) H_CBX8-a1
type: Assay
has participant: A-AFFY-45

Tmem51 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01727148099419
p value: 0.0180646678325981
refers to: 1424383_at
refers to: Tmem51
t statistic: 6.67851483497609

Fmod UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1749752377102
p value: 0.00624295144795875
refers to: Fmod
refers to: 1456084_x_at
t statistic: 9.8056629840793

(Sample) genetic modification/none
type: EFO_0001461
property type: genetic modification
property value: none

Tgfbi UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.14778331332941
p value: 0.016151836418625
refers to: Tgfbi
refers to: 1456250_x_at
t statistic: 6.90951610783213

1434275_at
type: EFO_0005072
part of: A-AFFY-45

Emilin2
type: EnsemblDatabaseReference

Nsg1
type: EnsemblDatabaseReference

Tgfbi UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.07010596746057
p value: 0.0102001249648636
refers to: 1415871_at
refers to: Tgfbi
t statistic: 8.29674257009344

Nsg1
type: EnsemblDatabaseReference

1448201_at
type: EFO_0005072
part of: A-AFFY-45

Nkd2
type: EnsemblDatabaseReference

Mest UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.19306129241123
p value: 0.0204579495393651
refers to: Mest
refers to: 1423294_at
t statistic: 6.4487321687074

Ccl7
type: EnsemblDatabaseReference

Nkd2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01832958521765
p value: 0.0153861089925457
refers to: 1434275_at
refers to: Nkd2
t statistic: 7.06453069794695

Ccl2
type: EnsemblDatabaseReference

Aqp1
type: EnsemblDatabaseReference

Dchs1
type: EnsemblDatabaseReference

(Sample) strain/C57BL/6
type: EFO_0004472
property type: strain
property value: C57BL/6

Ivl
type: EnsemblDatabaseReference

1424383_at
type: EFO_0005072
part of: A-AFFY-45

1452114_s_at
type: EFO_0005072
part of: A-AFFY-45

(Sample) genetic modification/gene knock in
type: EFO_0004963
property type: genetic modification
property value: gene knock in

Igfbp5
type: EnsemblDatabaseReference

(Sample) genotype/BMI1 over-expression
type: EFO_0000001
property type: genotype
property value: BMI1 over-expression

1423954_at
type: EFO_0005072
part of: A-AFFY-45

Tgfbi UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.31495717519448
p value: 0.0102001249648636
refers to: 1448123_s_at
refers to: Tgfbi
t statistic: 8.18979884222754

Mmp3
type: EnsemblDatabaseReference

(Sample) developmental stage/embryo
type: EFO_0001367
property type: developmental stage
property value: embryo

Mmp3
type: EnsemblDatabaseReference

1500015O10Rik
type: EnsemblDatabaseReference

Tgfbi
type: EnsemblDatabaseReference

(Assay) H_Mock-c1
type: Assay
has participant: A-AFFY-45

1427004_at
type: EFO_0005072
part of: A-AFFY-45

Cpxm2
type: EnsemblDatabaseReference

Fbxo2
type: EnsemblDatabaseReference

Gstt1
type: EnsemblDatabaseReference

Igfbp3
type: EnsemblDatabaseReference

Col8a2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.81875299315545
p value: 0.00434287864818425
refers to: Col8a2
refers to: 1434667_at
t statistic: 11.4055610453704

Fbxo2
type: EnsemblDatabaseReference

Ada
type: EnsemblDatabaseReference

1437463_x_at
type: EFO_0005072
part of: A-AFFY-45

Clu
type: EnsemblDatabaseReference

1415939_at
type: EFO_0005072
part of: A-AFFY-45

1434758_at
type: EFO_0005072
part of: A-AFFY-45

1424923_at
type: EFO_0005072
part of: A-AFFY-45

1434667_at
type: EFO_0005072
part of: A-AFFY-45

Crip1
type: EnsemblDatabaseReference

Syce2
type: EnsemblDatabaseReference

1439878_at
type: EFO_0005072
part of: A-AFFY-45

Emilin2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.27036078304608
p value: 0.0102001249648636
refers to: Emilin2
refers to: 1435264_at
t statistic: 8.12349959722527

Lce1f DOWN in 'BMI1 over-expression' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19571401512682
p value: 0.0172576747732375
refers to: Lce1f
refers to: 1420550_at
t statistic: -6.8188285253293

C3
type: EnsemblDatabaseReference

Syce2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.61599848082882
p value: 0.0210374436920095
refers to: Syce2
refers to: 1429270_a_at
t statistic: 6.36288330115136

Cdh6
type: EnsemblDatabaseReference

1420550_at
type: EFO_0005072
part of: A-AFFY-45

1448326_a_at
type: EFO_0005072
part of: A-AFFY-45

1453092_at
type: EFO_0005072
part of: A-AFFY-45

Crispld2
type: EnsemblDatabaseReference

Crispld2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.23766671558489
p value: 0.00424283574728367
refers to: Crispld2
refers to: 1437056_x_at
t statistic: 13.351036442011

Clu UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.32451826243384
p value: 0.0142422675298645
refers to: Clu
refers to: 1437689_x_at
t statistic: 7.29425773132852

(Assay) H_CBX8-c1
type: Assay
has participant: A-AFFY-45

1456084_x_at
type: EFO_0005072
part of: A-AFFY-45

Rbp1
type: EnsemblDatabaseReference

Tmem51
type: EnsemblDatabaseReference

E-MEXP-793
type: microarray 1colour mrna differential
RO_0002162: Mus musculus
description: The polycomb group proteins form large repressive complexes. It has recently become evident, via ChIP on chip analysis, that the polycomb complexes, PRC1 and PRC2, target a large number of genes (Boyer et al., 2006; Bracken et al., 2006; Tolhuis et al., 2006), which are involved in cell fate decisions. In order to identify genes which are truly regulated by the polycomb group proteins, CBX8 and BMI1, we expressed these two proteins in mouse embryonic fibroblasts (MEFs) by retroviral infection.
uses data from: http://identifiers.org/pubmed/17332741

(Assay) H_BMI1-b1
type: Assay
has participant: A-AFFY-45

Fmod
type: EnsemblDatabaseReference

Igfbp3 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.79522283909913
p value: 0.0108003964790406
refers to: Igfbp3
refers to: 1423062_at
t statistic: 7.89055780556646

1448194_a_at
type: EFO_0005072
part of: A-AFFY-45

Tmem51
type: EnsemblDatabaseReference

Fmod
type: EnsemblDatabaseReference

Crispld2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08666208061863
p value: 0.0102001249648636
refers to: 1460458_at
refers to: Crispld2
t statistic: 8.056593640022

Cpxm2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.40184698312209
p value: 0.0321683638893856
refers to: 1460248_at
refers to: Cpxm2
t statistic: 5.6805193648522

Fmod UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.22889687695838
p value: 0.0102001249648636
refers to: 1437685_x_at
refers to: Fmod
t statistic: 8.11760725834336

Col8a2
type: EnsemblDatabaseReference

Tspan11 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01929865846993
p value: 0.0484645544118725
refers to: 1430310_at
refers to: Tspan11
t statistic: 5.02018217519633

Col8a2
type: EnsemblDatabaseReference

Nppb
type: EnsemblDatabaseReference

1448754_at
type: EFO_0005072
part of: A-AFFY-45

Nppb
type: EnsemblDatabaseReference

(Sample) organism/Mus musculus
type: Mus musculus
property type: organism
property value: Mus musculus

Crabp1
type: EnsemblDatabaseReference

Serpina3g UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 2.02236197619511
p value: 0.00434111361028686
refers to: Serpina3g
refers to: 1424923_at
t statistic: 11.7918559530619

Fmod UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.24007558454003
p value: 0.0102001249648636
refers to: Fmod
refers to: 1437718_x_at
t statistic: 8.16830744443313

(Sample) biosource type/fresh specimen
type: EFO_0000001
property type: biosource type
property value: fresh specimen

Dchs1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13409376313417
p value: 0.00721548608773393
refers to: 1429163_at
refers to: Dchs1
t statistic: 9.47604825282347

1438989_s_at
type: EFO_0005072
part of: A-AFFY-45

1430310_at
type: EFO_0005072
part of: A-AFFY-45

Sfrp1
type: EnsemblDatabaseReference

Nsg1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.05639949470034
p value: 0.00904746437853786
refers to: 1423055_at
refers to: Nsg1
t statistic: 8.99566090600483

Nppb DOWN in 'BMI1 over-expression' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08453668056579
p value: 0.0100425793921528
refers to: Nppb
refers to: 1450791_at
t statistic: -8.56919475450658

Ivl DOWN in 'BMI1 over-expression' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.11961241926687
p value: 0.0108723409298194
refers to: Ivl
refers to: 1439878_at
t statistic: -7.80023068254781

Tspan11
type: EnsemblDatabaseReference

1429163_at
type: EFO_0005072
part of: A-AFFY-45

Crip1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 2.05490057522966
p value: 0.00618916580612581
refers to: 1416326_at
refers to: Crip1
t statistic: 10.4088577124084

Mmp3 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.95818136826466
p value: 0.00601261097608616
refers to: Mmp3
refers to: 1418945_at
t statistic: 10.5755215125933

1437324_x_at
type: EFO_0005072
part of: A-AFFY-45

1416203_at
type: EFO_0005072
part of: A-AFFY-45

1460248_at
type: EFO_0005072
part of: A-AFFY-45

1449939_s_at
type: EFO_0005072
part of: A-AFFY-45

1458268_s_at
type: EFO_0005072
part of: A-AFFY-45

Dlk1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.84285372037691
p value: 0.00424283574728367
refers to: 1449939_s_at
refers to: Dlk1
t statistic: 13.3479912343023

(Sample) cell type/primary embryonic fibroblasts
type: CL_0000057
property type: cell type
property value: primary embryonic fibroblasts

Nkd2
type: EnsemblDatabaseReference

Icam1
type: EnsemblDatabaseReference

Pdgfra UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.33908585038865
p value: 0.0095822209830715
refers to: Pdgfra
refers to: 1421917_at
t statistic: 8.70582522691558

Ccl7
type: EnsemblDatabaseReference

H19 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0020247519427
p value: 0.0102001249648636
refers to: 1448194_a_at
refers to: H19
t statistic: 8.2233474242737

Analysis of 'BMI1 over-expression' vs 'empty vector'
type: MicroarrayDifferentialExpressionAnalysis

(Sample) initial time point/coitus
type: EFO_0000001
property type: initial time point
property value: coitus

Igfbp5
type: EnsemblDatabaseReference

Lce1f
type: EnsemblDatabaseReference

Sfrp2
type: EnsemblDatabaseReference

Mest
type: EnsemblDatabaseReference

(Assay) H_Mock-b1
type: Assay
has participant: A-AFFY-45

Lce1f
type: EnsemblDatabaseReference

Sfrp2
type: EnsemblDatabaseReference

Dlk1
type: EnsemblDatabaseReference

1500015O10Rik
type: EnsemblDatabaseReference

Dlk1
type: EnsemblDatabaseReference

Emilin2
type: EnsemblDatabaseReference

Igfbp3 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.06110465919969
p value: 0.0218422457821926
refers to: 1458268_s_at
refers to: Igfbp3
t statistic: 6.30583440140458

Igfbp3
type: EnsemblDatabaseReference

Fmod UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13085467160477
p value: 0.0102001249648636
refers to: 1437324_x_at
refers to: Fmod
t statistic: 8.0984344776753

1460049_s_at
type: EFO_0005072
part of: A-AFFY-45

1415871_at
type: EFO_0005072
part of: A-AFFY-45

Clu
type: EnsemblDatabaseReference

Ccl2
type: EnsemblDatabaseReference

Aqp1
type: EnsemblDatabaseReference

Dchs1
type: EnsemblDatabaseReference

Sfrp2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 3.22012488701587
p value: 2.67506062814229E-5
refers to: Sfrp2
refers to: 1448201_at
t statistic: 34.7632852415818

Ivl
type: EnsemblDatabaseReference

Serpina3g
type: EnsemblDatabaseReference

Syce2
type: EnsemblDatabaseReference

1428136_at
type: EFO_0005072
part of: A-AFFY-45

C3 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.17025349737852
p value: 0.0102001249648636
refers to: C3
refers to: 1423954_at
t statistic: 8.04333894705922

Serpina3g
type: EnsemblDatabaseReference

1456250_x_at
type: EFO_0005072
part of: A-AFFY-45

1423294_at
type: EFO_0005072
part of: A-AFFY-45

1423055_at
type: EFO_0005072
part of: A-AFFY-45

1460458_at
type: EFO_0005072
part of: A-AFFY-45

1421228_at
type: EFO_0005072
part of: A-AFFY-45

1418186_at
type: EFO_0005072
part of: A-AFFY-45

Cdh6
type: EnsemblDatabaseReference

(Assay) H_BMI1-a1
type: Assay
has participant: A-AFFY-45

Tgfbi
type: EnsemblDatabaseReference

A-AFFY-45
type: EFO_0000269

Cpxm2
type: EnsemblDatabaseReference

(Factor value) GENOTYPE/BMI1 over-expression
type: EFO_0000001
property type: GENOTYPE
property value: BMI1 over-expression

Gstt1
type: EnsemblDatabaseReference

Ccl7 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.33962104615887
p value: 0.00424283574728367
refers to: Ccl7
refers to: 1421228_at
t statistic: 14.255297140569

Crispld2
type: EnsemblDatabaseReference

1420380_at
type: EFO_0005072
part of: A-AFFY-45

Ada
type: EnsemblDatabaseReference

Ada UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13141704013498
p value: 0.00434111361028686
refers to: 1417976_at
refers to: Ada
t statistic: 11.8164074534523

1500015O10Rik UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.09918268517393
p value: 0.0308981485339425
refers to: 1500015O10Rik
refers to: 1460049_s_at
t statistic: 5.72894274294179

Crabp1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.70426808423484
p value: 0.00434111361028686
refers to: Crabp1
refers to: 1448326_a_at
t statistic: 12.1856317795864

1416326_at
type: EFO_0005072
part of: A-AFFY-45

H19
type: EnsemblDatabaseReference

H19
type: EnsemblDatabaseReference

1437056_x_at
type: EFO_0005072
part of: A-AFFY-45

Mus musculus
type: OBI_0100026

1429270_a_at
type: EFO_0005072
part of: A-AFFY-45

Crip1
type: EnsemblDatabaseReference

(Sample) genotype/CBX8 over-expression
type: EFO_0000001
property type: genotype
property value: CBX8 over-expression

Crct1 DOWN in 'BMI1 over-expression' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08039433469406
p value: 0.0417617025955181
refers to: Crct1
refers to: 1453092_at
t statistic: -5.24099138947401

Gstt1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.16443171746282
p value: 0.0095822209830715
refers to: 1418186_at
refers to: Gstt1
t statistic: 8.67930367840475

1437685_x_at
type: EFO_0005072
part of: A-AFFY-45

C3
type: EnsemblDatabaseReference

Rbp1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03235270149985
p value: 0.0205296311944997
refers to: Rbp1
refers to: 1448754_at
t statistic: 6.43113283416757

(Sample) age/13.5
type: EFO_0000001
property type: age
property value: 13.5

(Assay) H_BMI1-c1
type: Assay
has participant: A-AFFY-45

1437689_x_at
type: EFO_0005072
part of: A-AFFY-45

Cdh6 DOWN in 'BMI1 over-expression' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19535593207063
p value: 0.0263714517969321
refers to: Cdh6
refers to: 1438989_s_at
t statistic: -6.03623087850865

Aqp1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.67350208281327
p value: 0.00434111361028686
refers to: Aqp1
refers to: 1416203_at
t statistic: 11.9522266825659

Tgfbi UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11977703428819
p value: 0.00622698965946276
refers to: Tgfbi
refers to: 1437463_x_at
t statistic: 10.288905277661

Sfrp1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.15562378811616
p value: 0.00904746437853786
refers to: Sfrp1
refers to: 1428136_at
t statistic: 9.0226733816857

(Factor value) GENOTYPE/CBX8 over-expression
type: EFO_0000001
property type: GENOTYPE
property value: CBX8 over-expression

Rbp1
type: EnsemblDatabaseReference

1417976_at
type: EFO_0005072
part of: A-AFFY-45

1448123_s_at
type: EFO_0005072
part of: A-AFFY-45

1423062_at
type: EFO_0005072
part of: A-AFFY-45

Tspan11
type: EnsemblDatabaseReference

1424067_at
type: EFO_0005072
part of: A-AFFY-45

(Sample) genotype/empty vector
type: EFO_0000001
property type: genotype
property value: empty vector

Icam1 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11496697661163
p value: 0.00624295144795875
refers to: Icam1
refers to: 1424067_at
t statistic: 10.0658734670121

1421917_at
type: EFO_0005072
part of: A-AFFY-45

Crispld2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.16082451833893
p value: 0.00624295144795875
refers to: Crispld2
refers to: 1434758_at
t statistic: 10.1387920916068

Fmod UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11691819091377
p value: 0.00434287864818425
refers to: Fmod
refers to: 1415939_at
t statistic: 11.4947707511905

Ccl2 UP in 'BMI1 over-expression' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0508371489087
p value: 0.00434111361028686
refers to: 1420380_at
refers to: Ccl2
t statistic: 11.7612389822838

Crabp1
type: EnsemblDatabaseReference

Icam1
type: EnsemblDatabaseReference

(Assay) H_Mock-a1
type: Assay
has participant: A-AFFY-45

Crct1
type: EnsemblDatabaseReference

1418945_at
type: EFO_0005072
part of: A-AFFY-45