APBA2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SOX4 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
LTBP3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KLRB1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
TNFSF10 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SCML1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IL6ST DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CHI3L2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
IFI6 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
RTP4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SMC4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MLXIP DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
NR3C2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
KIAA0101 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
LEF1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RBM38 DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
HSPB11 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
EIF2AK2 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
GMNN UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CENPM UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SC5D DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LYST UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI27 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
MCM5 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
DUSP8 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LAG3 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PIK3IP1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PTP4A1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFIT3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
SLC27A2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TOP2A UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLSCR1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
PER1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
XAF1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
MX1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
CASP7 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ATP6V1D UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TYMP UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
MX1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
SMAD7 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CDK1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GIMAP4 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
BTG2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PRDX3 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI27 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
RFC4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RAD51AP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RSAD2 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
RNF130 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CBX7 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
Analysis of 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
CCNA2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
FBXO5 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RSAD2 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
BACH2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
TTC3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NR4A2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IL6ST DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SORL1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TSC22D2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SYPL1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ACOT7 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFRD1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
MCM7 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PTCH1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
DDX60 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
SPATS2L UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
SH2D1A UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Factor value) DISEASE/chronic HIV infection
FAM13A UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
SMAD7 DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
ZSCAN18 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZBTB18 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
DEFA4 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
PIK3IP1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
MAD2L1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
EIF2AK2 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
CENPU UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLP2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NUSAP1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N141-CD8+ T cells
Human Uninfected Sample N141-CD8+ T cells
SLAMF7 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44L UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
CD55 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CAND1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RP11-553L6.5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MCM4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IRS2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
Analysis of 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
HERC6 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
OSER1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MX1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PYCARD UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LEF1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44L UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
IER5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MKI67 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLSCR1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RSAD2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ASF1B UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A051-CD4+ T cells
Human Acute HIV Sample A051-CD4+ T cells
ASPM UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TNFSF10 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
HSPA1A UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
HERC5 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
CRY1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
NT5E DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
AOAH UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
KIF11 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LAMP3 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
MXI1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KLF9 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CDC20 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PSMA4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CHI3L2 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
PCNA UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C080-CD8+ T cells
Human Chronic HIV Sample C080-CD8+ T cells
We examined the gene expression profiles in ex vivo human CD4+ and CD8+ T cells from untreated HIV-infected individuals at different clinical stages and rates of disease progression. Profiles of pure CD4+ and CD8+ T cells subsets from HIV-infected nonprogressors who controlled viremia were indistinguishable from HIV-uninfected individuals. Similarly, no gene clusters could distinguish T cells from individuals with early from chronic progressive HIV infection, whereas differences were observed between uninfected or nonprogressors versus early or chronic progressors. In early/chronic HIV infection, three characteristic gene expression signatures were observed: (1) CD4+ and CD8+ T cells showed increased expression of interferon stimulated genes (ISGs). However, some ISGs including CXCL9, CXCL10, and CXCL11, and the IL15R? in both CD4+ and CD8+ T cells and the anti-HIV ISG APOBEC3G in CD4+ T cells, were not upregulated. (2) CD4+ and CD8+ T cells showed a cluster similar to that observed in thymocytes, and (3) more genes were differentially regulated in CD8+ T cells than in CD4+ T cells, including a cluster of genes downregulated exclusively in CD8+ T cells. In conclusion, HIV infection induces a persistent T cell transcriptional profile, early in infection, characterized by a dramatic but potentially aberrant interferon response, and a profile suggesting an active thymic output. We studied a cohort of HIV infected individuals with various clinical stages of HIV infection and healthy uninfected volunteers as a control group (Table 1). We included 5 individuals with early HIV infection (A), five with chronic progressive HIV infection (C), five individuals with non-progressive HIV infection with low or undetectable viral loads (L) and five HIV uninfected individuals (N). The HIV infected individuals were never on therapy prior to entering the study. Samples were taken once from each donor.
(Assay) Human Chronic HIV Sample C138-CD4+ T cells
Human Chronic HIV Sample C138-CD4+ T cells
IFI6 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Chronic HIV Sample C062-CD4+ T cells
Human Chronic HIV Sample C062-CD4+ T cells
(Factor value) CELL_TYPE/CD4-positive T cell
CENPF UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SMC2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
Analysis of 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
MCM6 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L134-CD4+ T cells
Human Non-progressor HIV Sample L134-CD4+ T cells
PLEK UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Sample) disease/non-progressive HIV infection
KLF11 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CCR5 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A051-CD8+ T cells
Human Acute HIV Sample A051-CD8+ T cells
PLEKHB1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SGK1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
BIRC5 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD55 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CCR5 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PTTG1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ISG15 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
HLA-DRA UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NUSAP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GTF2H1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N001-CD8+ T cells
Human Uninfected Sample N001-CD8+ T cells
NDC80 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PRKCA DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IGF1R DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CUX1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SNN DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PRKCA DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L004-CD4+ T cells
Human Non-progressor HIV Sample L004-CD4+ T cells
HERC6 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
MAFF DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KIAA0101 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
DDX60 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CLDND1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
MELK UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GPRASP1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
BTG2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
GNAQ DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLSCR1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
HLA-DMA UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
STAT1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
C6orf211 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFNGR1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
RGCC DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GADD45B DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LYZ DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
FEN1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L128-CD4+ T cells
Human Non-progressor HIV Sample L128-CD4+ T cells
GPR171 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Acute HIV Sample A044-CD8+ T cells
Human Acute HIV Sample A044-CD8+ T cells
FANCI UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N141-CD4+ T cells
Human Uninfected Sample N141-CD4+ T cells
NAP1L3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PTP4A1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NT5E DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
SKIL DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LGALS9 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RRM2 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Non-progressor HIV Sample L128-CD8+ T cells
Human Non-progressor HIV Sample L128-CD8+ T cells
(Assay) Human Acute HIV Sample A064-CD8+ T cells
Human Acute HIV Sample A064-CD8+ T cells
(Assay) Human Non-progressor HIV Sample L015-CD8+ T cells
Human Non-progressor HIV Sample L015-CD8+ T cells
ISG15 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
IFI16 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZFP36L2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
GZMA UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
STAT1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
CKS2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CDKN1A DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
GADD45A DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IRS2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
MEST DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
SP140 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
LMNB1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI35 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
TAP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PDE4B DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
RBM38 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SMAD7 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GINS1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MEST DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TPX2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IRF7 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CASP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GPR171 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SRP54 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
DLGAP5 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KLF11 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
AREG DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
TRAV13-1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KLRF1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD160 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
TYMS UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
ZNF571 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZSCAN18 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MCM2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N050-CD8+ T cells
Human Uninfected Sample N050-CD8+ T cells
GIMAP4 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CGRRF1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NR4A3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NUP43 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFRD1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLCG2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CDKN3 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LAMP3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
AREG DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PDE4B DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IL7R DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CDKN1A DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RBBP8 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SLC2A3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LYPD3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RAD51 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IDH2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
WHSC1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NAP1L3 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CKAP4 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
S1PR1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TGIF1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFIT3 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
ZBTB10 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L115-CD4+ T cells
Human Non-progressor HIV Sample L115-CD4+ T cells
CDKN1A DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
OAS3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
CDC7 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
EIF5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MX1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
NUP37 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI27 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
DTL UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N050-CD4+ T cells
Human Uninfected Sample N050-CD4+ T cells
ITGA6 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
TSC22D3 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C080-CD4+ T cells
Human Chronic HIV Sample C080-CD4+ T cells
SKIL DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
PRC1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
HERC5 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZNF395 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TYMS UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CCR7 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
PFKFB3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
GINS2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NRIP1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
C6orf211 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
SMC1A UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IRF7 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Uninfected Sample N071-CD4+ T cells
Human Uninfected Sample N071-CD4+ T cells
JMJD6 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NUSAP1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
PRKD3 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
S100A8 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
SUCLA2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
LAG3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZBTB10 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFNG UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C101-CD8+ T cells
Human Chronic HIV Sample C101-CD8+ T cells
(Assay) Human Chronic HIV Sample C102-CD8+ T cells
Human Chronic HIV Sample C102-CD8+ T cells
POU2AF1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
BCL11B DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZNF91 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI35 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TCEAL4 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NME4 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SSBP2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MRPL13 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Factor value) DISEASE/early HIV infection
LGALS9 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CEP55 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI6 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
GADD45A DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CHPT1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
FAM134B DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD38 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CCNB1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
YWHAE UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
DENND2D UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PSMB2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A044-CD4 T cells
ZWILCH UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
COL6A2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD38 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Factor value) DISEASE/non-progressive HIV infection
IFIT1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
TPD52 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
SPATS2L UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ACTN1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
POU2AF1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Uninfected Sample N110-CD4+ T cells
Human Uninfected Sample N110-CD4+ T cells
ZNF91 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CLDND1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CSGALNACT1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
ADA UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI6 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RRM1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
COTL1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
STAT1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C062-CD8+ T cells
Human Chronic HIV Sample C062-CD8+ T cells
FXYD5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ISG15 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GADD45A DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
SLC7A5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TSC22D3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLK3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L115-CD8+ T cells
Human Non-progressor HIV Sample L115-CD8+ T cells
RACGAP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L134-CD8+ T cells
Human Non-progressor HIV Sample L134-CD8+ T cells
STMN1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A189-CD8+ T cells
Human Acute HIV Sample A189-CD8+ T cells
LTBP3 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD24 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Acute HIV Sample A144-CD4+ T cells
Human Acute HIV Sample A144-CD4+ T cells
JUND DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SNN DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
BCL11B DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A064-CD4+ T cells
Human Acute HIV Sample A064-CD4+ T cells
MTHFD1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CKAP4 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
HN1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CCNB2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L015-CD4+ T cells
Human Non-progressor HIV Sample L015-CD4+ T cells
(Assay) Human Chronic HIV Sample C102-CD4+ T cells
Human Chronic HIV Sample C102-CD4+ T cells
PRNP DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NAA16 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N001-CD4+ T cells
Human Uninfected Sample N001-CD4+ T cells
GBP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
XAF1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
D4S234E DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TGIF1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
DGKA DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ISG15 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44L UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Acute HIV Sample A144-CD8+ T cells
Human Acute HIV Sample A144-CD8+ T cells
RRM2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CD9 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
HSPA1A UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GBP1 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Acute HIV Sample A189-CD4+ T cells
Human Acute HIV Sample A189-CD4+ T cells
NELL2 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
UBE2C UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
EZH2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
RSAD2 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
OASL UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
XAF1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NCAPG2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NR3C2 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Non-progressor HIV Sample L004-CD8+ T cells
Human Non-progressor HIV Sample L004-CD8+ T cells
CISD1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZNF331 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
NRIP1 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
PAICS UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SLC7A5 DOWN in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
IFI27 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Uninfected Sample N071-CD8+ T cells
Human Uninfected Sample N071-CD8+ T cells
Analysis of 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
(Assay) Human Uninfected Sample N110-CD8+ T cells
Human Uninfected Sample N110-CD8+ T cells
MRPL15 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SCO2 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
ETNK1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
TFDP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
HMMR UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
AIM2 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
SLC25A20 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C101-CD4+ T cells
Human Chronic HIV Sample C101-CD4+ T cells
SOX4 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
GABARAPL1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IGJ UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZWINT UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
MCM10 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
BHLHE40 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFIT3 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
RGCC DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
BEX4 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
DDX60 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
SMAD7 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
HERC5 UP in 'chronic HIV infection' vs 'uninfected' in 'CD4+ T cell'
NCBP1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
ZBTB18 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
C3orf14 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KLF9 DOWN in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
PFKFB3 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
OAS2 UP in 'early HIV infection' vs 'uninfected' in 'CD4+ T cell'
SCML1 DOWN in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
PLSCR1 UP in 'chronic HIV infection' vs 'uninfected' in 'CD8+ T cell'
IFI44L UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
(Assay) Human Chronic HIV Sample C138-CD8+ T cells
Human Chronic HIV Sample C138-CD8+ T cells
MYL6B UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
KIF15 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'
CX3CR1 UP in 'early HIV infection' vs 'uninfected' in 'CD8+ T cell'