ADAMDEC1 DOWN in 'ulcerative colitis' vs 'normal'
NCOA3 DOWN in 'ulcerative colitis' vs 'normal'
DYRK2 DOWN in 'ulcerative colitis' vs 'normal'
SPAG9 DOWN in 'ulcerative colitis' vs 'normal'
FGF9 DOWN in 'ulcerative colitis' vs 'normal'
NEDD4L DOWN in 'ulcerative colitis' vs 'normal'
RND3 DOWN in 'ulcerative colitis' vs 'normal'
TOPORS DOWN in 'ulcerative colitis' vs 'normal'
SPON1 DOWN in 'ulcerative colitis' vs 'normal'
TERF1 DOWN in 'ulcerative colitis' vs 'normal'
PTGDR DOWN in 'Crohn's disease' vs 'normal'
ZNF148 DOWN in 'Crohn's disease' vs 'normal'
VLDLR DOWN in 'ulcerative colitis' vs 'normal'
SNX13 DOWN in 'ulcerative colitis' vs 'normal'
TMEM47 DOWN in 'Crohn's disease' vs 'normal'
RP11-553L6.5 DOWN in 'Crohn's disease' vs 'normal'
F2RL1 DOWN in 'ulcerative colitis' vs 'normal'
PTPRR DOWN in 'ulcerative colitis' vs 'normal'
AFF1 DOWN in 'ulcerative colitis' vs 'normal'
IGFBP2 UP in 'ulcerative colitis' vs 'normal'
STAT3 UP in 'Crohn's disease' vs 'normal'
PKN2 DOWN in 'ulcerative colitis' vs 'normal'
KIAA1109 DOWN in 'ulcerative colitis' vs 'normal'
TMBIM6 DOWN in 'ulcerative colitis' vs 'normal'
UGT2B7 DOWN in 'ulcerative colitis' vs 'normal'
SERPINA1 UP in 'Crohn's disease' vs 'normal'
SATB2 DOWN in 'ulcerative colitis' vs 'normal'
RSBN1 DOWN in 'ulcerative colitis' vs 'normal'
NR1D2 DOWN in 'Crohn's disease' vs 'normal'
PPP2R5E DOWN in 'ulcerative colitis' vs 'normal'
PGAP1 DOWN in 'ulcerative colitis' vs 'normal'
UGT8 DOWN in 'ulcerative colitis' vs 'normal'
TFRC DOWN in 'ulcerative colitis' vs 'normal'
LCN2 UP in 'Crohn's disease' vs 'normal'
LEPROT DOWN in 'ulcerative colitis' vs 'normal'
DDX17 DOWN in 'Crohn's disease' vs 'normal'
MAX DOWN in 'ulcerative colitis' vs 'normal'
CLDN8 DOWN in 'ulcerative colitis' vs 'normal'
CMAHP DOWN in 'ulcerative colitis' vs 'normal'
PANK3 DOWN in 'ulcerative colitis' vs 'normal'
CITED2 DOWN in 'ulcerative colitis' vs 'normal'
LGALS2 DOWN in 'ulcerative colitis' vs 'normal'
STMN2 DOWN in 'Crohn's disease' vs 'normal'
TAOK3 DOWN in 'ulcerative colitis' vs 'normal'
ABCA8 DOWN in 'ulcerative colitis' vs 'normal'
PECAM1 UP in 'ulcerative colitis' vs 'normal'
PLOD2 DOWN in 'Crohn's disease' vs 'normal'
MAPT UP in 'ulcerative colitis' vs 'normal'
SEMA6A DOWN in 'Crohn's disease' vs 'normal'
PKN2 DOWN in 'Crohn's disease' vs 'normal'
PRKACB DOWN in 'ulcerative colitis' vs 'normal'
DICER1 DOWN in 'ulcerative colitis' vs 'normal'
HAPLN1 DOWN in 'Crohn's disease' vs 'normal'
CREBL2 DOWN in 'ulcerative colitis' vs 'normal'
ACSL3 DOWN in 'ulcerative colitis' vs 'normal'
CREB1 DOWN in 'ulcerative colitis' vs 'normal'
ZC3H14 DOWN in 'ulcerative colitis' vs 'normal'
PRDX6 DOWN in 'ulcerative colitis' vs 'normal'
TNPO1 DOWN in 'Crohn's disease' vs 'normal'
SEMA6A DOWN in 'ulcerative colitis' vs 'normal'
ZC3H13 DOWN in 'ulcerative colitis' vs 'normal'
MED13 DOWN in 'ulcerative colitis' vs 'normal'
RMND5A DOWN in 'ulcerative colitis' vs 'normal'
SNX13 DOWN in 'Crohn's disease' vs 'normal'
PTPRD DOWN in 'ulcerative colitis' vs 'normal'
(Factor value) DISEASE/indeterminate colitis
PRKACB DOWN in 'Crohn's disease' vs 'normal'
HIST1H4C DOWN in 'ulcerative colitis' vs 'normal'
MXI1 DOWN in 'ulcerative colitis' vs 'normal'
DYRK2 DOWN in 'Crohn's disease' vs 'normal'
PPP2R3A DOWN in 'ulcerative colitis' vs 'normal'
COBL DOWN in 'ulcerative colitis' vs 'normal'
CORO1A UP in 'ulcerative colitis' vs 'normal'
EMP1 DOWN in 'ulcerative colitis' vs 'normal'
GPD2 DOWN in 'ulcerative colitis' vs 'normal'
FAM8A1 DOWN in 'ulcerative colitis' vs 'normal'
(Factor value) DISEASE/ulcerative colitis
PDE3B DOWN in 'ulcerative colitis' vs 'normal'
APPBP2 DOWN in 'ulcerative colitis' vs 'normal'
TYMP UP in 'ulcerative colitis' vs 'normal'
CALM1 DOWN in 'ulcerative colitis' vs 'normal'
DICER1 DOWN in 'Crohn's disease' vs 'normal'
ADD3 DOWN in 'ulcerative colitis' vs 'normal'
EDN3 DOWN in 'ulcerative colitis' vs 'normal'
LPCAT1 UP in 'Crohn's disease' vs 'normal'
MUT DOWN in 'ulcerative colitis' vs 'normal'
NCOA3 DOWN in 'Crohn's disease' vs 'normal'
ADD3 DOWN in 'Crohn's disease' vs 'normal'
KDM5A DOWN in 'ulcerative colitis' vs 'normal'
DSC2 DOWN in 'ulcerative colitis' vs 'normal'
CHD1 DOWN in 'Crohn's disease' vs 'normal'
GNAQ DOWN in 'ulcerative colitis' vs 'normal'
SLC4A4 DOWN in 'ulcerative colitis' vs 'normal'
REG1A UP in 'ulcerative colitis' vs 'normal'
Analysis of 'ulcerative colitis' vs 'normal'
SNX4 DOWN in 'ulcerative colitis' vs 'normal'
TSPAN6 DOWN in 'ulcerative colitis' vs 'normal'
KCTD12 DOWN in 'ulcerative colitis' vs 'normal'
TNPO1 DOWN in 'ulcerative colitis' vs 'normal'
KIF5B DOWN in 'ulcerative colitis' vs 'normal'
PTN DOWN in 'Crohn's disease' vs 'normal'
ENPP1 DOWN in 'Crohn's disease' vs 'normal'
RP11-553L6.5 DOWN in 'ulcerative colitis' vs 'normal'
GNAQ DOWN in 'Crohn's disease' vs 'normal'
AHCYL1 DOWN in 'ulcerative colitis' vs 'normal'
KRAS DOWN in 'ulcerative colitis' vs 'normal'
SCAMP5 UP in 'ulcerative colitis' vs 'normal'
HAPLN1 DOWN in 'ulcerative colitis' vs 'normal'
TIPRL DOWN in 'Crohn's disease' vs 'normal'
PGAP1 DOWN in 'Crohn's disease' vs 'normal'
NCOA2 DOWN in 'ulcerative colitis' vs 'normal'
HOXA5 DOWN in 'ulcerative colitis' vs 'normal'
Ulcerative colitis (UC) and CrohnÃÂs disease (CD) are inflammatory bowel diseases (IBD) with variable, overlapping clinical features and complex pathophysiologies. To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies to estabolish 36 expression profiles, we elucidated gene expression patterns of active and inactive areas of UC and CD, and compared these to infectious colitis and healthy controls.To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies, we elucidated gene expression patterns of active and inactive areas of UC and CD, and compared these to infectious colitis and healthy controls. An unsupervised classification of a total of 36 samples yielded promising separation between IBD affected, unaffected, non-IBD colitis and normal controls, suggesting distinctive gene expression patterns for each sample type. The Significance Analysis of Microarays (SAM) software to select biologically significant changes in gene expression between groups. The criteria selected for SAM analysis are, a median false discovery rate (FDR) ? 0.00001%, fold change >2, and a Log2 mean expression index > 6.64.
MAX DOWN in 'Crohn's disease' vs 'normal'
ANK3 DOWN in 'Crohn's disease' vs 'normal'
FMO5 DOWN in 'ulcerative colitis' vs 'normal'
PTGDR DOWN in 'ulcerative colitis' vs 'normal'
(Factor value) DISEASE/infectious colitis
ZNF148 DOWN in 'ulcerative colitis' vs 'normal'
TIPRL DOWN in 'ulcerative colitis' vs 'normal'
PIP5K1B DOWN in 'ulcerative colitis' vs 'normal'
EXPH5 DOWN in 'ulcerative colitis' vs 'normal'
BBX DOWN in 'Crohn's disease' vs 'normal'
SLC5A3 DOWN in 'ulcerative colitis' vs 'normal'
SLC26A2 DOWN in 'ulcerative colitis' vs 'normal'
PPM1A DOWN in 'ulcerative colitis' vs 'normal'
NRIP1 DOWN in 'Crohn's disease' vs 'normal'
EXPH5 DOWN in 'Crohn's disease' vs 'normal'
PDE4D DOWN in 'ulcerative colitis' vs 'normal'
FPGT DOWN in 'ulcerative colitis' vs 'normal'
VPS13A DOWN in 'ulcerative colitis' vs 'normal'
MLLT3 DOWN in 'ulcerative colitis' vs 'normal'
SLC4A4 DOWN in 'Crohn's disease' vs 'normal'
GUCA2B DOWN in 'ulcerative colitis' vs 'normal'
GGH DOWN in 'ulcerative colitis' vs 'normal'
TERF1 DOWN in 'Crohn's disease' vs 'normal'
THOC2 DOWN in 'ulcerative colitis' vs 'normal'
ARHGAP5 DOWN in 'ulcerative colitis' vs 'normal'
DSC2 DOWN in 'Crohn's disease' vs 'normal'
ATP2B1 DOWN in 'ulcerative colitis' vs 'normal'
PDE4D DOWN in 'Crohn's disease' vs 'normal'
ZMYND11 DOWN in 'ulcerative colitis' vs 'normal'
H1F0 DOWN in 'ulcerative colitis' vs 'normal'
ZC3H13 DOWN in 'Crohn's disease' vs 'normal'
KLF10 DOWN in 'ulcerative colitis' vs 'normal'
TRIM2 DOWN in 'ulcerative colitis' vs 'normal'
ENPP1 DOWN in 'ulcerative colitis' vs 'normal'
IGFBP5 UP in 'ulcerative colitis' vs 'normal'
AZGP1 UP in 'ulcerative colitis' vs 'normal'
STRN DOWN in 'ulcerative colitis' vs 'normal'
SFRP1 DOWN in 'ulcerative colitis' vs 'normal'
SOSTDC1 DOWN in 'Crohn's disease' vs 'normal'
BBX DOWN in 'ulcerative colitis' vs 'normal'
PLOD2 DOWN in 'ulcerative colitis' vs 'normal'
PTN DOWN in 'ulcerative colitis' vs 'normal'
NCOA2 DOWN in 'Crohn's disease' vs 'normal'
NRIP1 DOWN in 'ulcerative colitis' vs 'normal'
SOSTDC1 DOWN in 'ulcerative colitis' vs 'normal'
VWF UP in 'ulcerative colitis' vs 'normal'
AKAP10 DOWN in 'ulcerative colitis' vs 'normal'
G3BP1 DOWN in 'ulcerative colitis' vs 'normal'
CCNG1 DOWN in 'ulcerative colitis' vs 'normal'
CHD1 DOWN in 'ulcerative colitis' vs 'normal'
TRAPPC8 DOWN in 'ulcerative colitis' vs 'normal'
CALM1 DOWN in 'Crohn's disease' vs 'normal'
ABCA8 DOWN in 'Crohn's disease' vs 'normal'
ITM2A DOWN in 'ulcerative colitis' vs 'normal'
EMP1 DOWN in 'Crohn's disease' vs 'normal'
NR1D2 DOWN in 'ulcerative colitis' vs 'normal'
Analysis of 'Crohn's disease' vs 'normal'
SRI DOWN in 'ulcerative colitis' vs 'normal'
ARHGAP5 DOWN in 'Crohn's disease' vs 'normal'
CFI UP in 'ulcerative colitis' vs 'normal'