Olr246 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
Prp15 UP in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Cyp4a1 UP in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
LOC689489 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Ccnb1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Etv3 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
AABR06040025.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
LOC100359700 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
RGD1566373 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Myh11 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
Tmem104 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
AABR06025093.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Hspa1a DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Myh11 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Analysis of 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Ephx2 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
LOC100365590 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Popdc2 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06068729.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Olr246 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
AABR06101952.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
To further investigate the potential molecular basis of the therapeutic effects of the mixture of salvianolic acids from Salvia miltiorrhiza and total flavonoids from Anemarrhena asphodeloides (MSTF) on sulfur mustard (SM) damage, gene expression analysis was conducted on rats liver tissues using microarrays. Rats were randomly assigned to one of the three following treatment groups (10 rats per group): normal control, SM and SM + MSTF. SM was dissolved in propylene glycol. The SM was applied with subcutaneous injection as a single dose of 3.5 mg/kg body weight equivalent to 0.7 LD50. The equivalent volume of solvent was given to control rats. MSTF (120 mg/kg body weight/day) dissolved in double distilled water were administered intragastrically to the rats 1 h after SM treatment. Twenty-four hours following SM treatment, the rats were subjected to anesthesia and then sacrificed by cervical dislocation. Liver was dissected out from each animal. 3-4 of these liver tissues were processed for the microarray experiment.
Nlrp1b UP in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Atp5hl1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Fgfr3 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
LOC100362391 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
(Factor value) INJURY/sulfur mustard damage
Pde3b DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06105618.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Elf2 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
(Factor value) COMPOUND/salvianolic acids from Salvia miltiorrhiza and total flavonoids from Anemarrhena asphodeloides 120
salvianolic acids from Salvia miltiorrhiza and total flavonoids from Anemarrhena asphodeloides 120
Rn50_14_0866.3 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Analysis of 'sulfur mustard damage' vs 'no damage' in 'none'
LOC100909605 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Nlrp1b DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
RT1-CE3 UP in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
RGD1561841 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Cdkn3 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06084464.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
RGD1564550 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Tmem52 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06067485.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Duoxa1 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06095497.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Elf2 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06007893.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Cox7c DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Trpv6 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
AABR06090099.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Fgfr3 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
Actc1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06102847.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06030189.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Nkd1 DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Gm5218 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06049090.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Kif20a DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Ccno DOWN in 'salvianolic acids from S. miltiorrhiza + total flavonoids from A. asphodeloides' vs 'none' in 'sulfur mustard damage'
Rn50_10_0627.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Ndufc2 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06040285.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06024026.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06044586.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Prp15 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
LOC503134 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'
Acsm3 UP in 'sulfur mustard damage' vs 'no damage' in 'none'
AABR06044220.1 DOWN in 'sulfur mustard damage' vs 'no damage' in 'none'