(Factor value) COMPOUND/biomineralized insulin
Analysis of 'biomineralized insulin' vs 'none'
Phlda1 DOWN in 'biomineralized insulin' vs 'none'
Slc25a30 DOWN in 'biomineralized insulin' vs 'none'
A4gnt UP in 'biomineralized insulin' vs 'none'
There is evidence indicating the involvement of DNA methylation memory in maintaining gene expression patterns associated with insulin resistance. Although the exact mechanism remains unknown, it has been proved that insulin resistance is correlated to low heat shock protein (HSP) expression. We reveal that intranuclear insulin can reduce HSP DNA methylation level to up-regulate HSP protein expression and result in long term cure of hyperglycemia. Type 2 diabetes KKAy mouse were selected in our experiments.Three conditions were compared with three replicates each. These are:(1) Untreated KKAy mouse (2) Insulin treated KKAy mouse(Insulin); (3) Biomineralized insulin treated KKAy mouse(BI).
Lyve1 UP in 'biomineralized insulin' vs 'none'
Socs3 DOWN in 'biomineralized insulin' vs 'none'
Gadd45g DOWN in 'biomineralized insulin' vs 'none'
Sema3c UP in 'biomineralized insulin' vs 'none'
Orm3 DOWN in 'biomineralized insulin' vs 'none'
Foxq1 DOWN in 'biomineralized insulin' vs 'none'
Serpine2 DOWN in 'biomineralized insulin' vs 'none'
Wsb1 DOWN in 'biomineralized insulin' vs 'none'
Cish DOWN in 'biomineralized insulin' vs 'none'
Fbln5 UP in 'biomineralized insulin' vs 'none'
Gm6484 UP in 'biomineralized insulin' vs 'none'
Elovl6 UP in 'biomineralized insulin' vs 'none'
Dnajc12 DOWN in 'biomineralized insulin' vs 'none'
Sbk1 UP in 'biomineralized insulin' vs 'none'
Lbp DOWN in 'biomineralized insulin' vs 'none'
(Sample) disease/type II diabetes mellitus
Gpm6a UP in 'biomineralized insulin' vs 'none'
Tmem30a DOWN in 'biomineralized insulin' vs 'none'
G0s2 UP in 'biomineralized insulin' vs 'none'
Pnpla3 UP in 'biomineralized insulin' vs 'none'
Etnppl UP in 'biomineralized insulin' vs 'none'
Col27a1 UP in 'biomineralized insulin' vs 'none'