COX7B UP in '16 micromolar; geneticin' vs 'none'
SDF2L1 UP in '16 micromolar; geneticin' vs 'none'
SPRED2 UP in '16 micromolar; geneticin' vs 'none'
SEPW1 UP in '16 micromolar; geneticin' vs 'none'
FAM175A DOWN in '16 micromolar; geneticin' vs 'none'
HSPA5 UP in '16 micromolar; geneticin' vs 'none'
In order to study the cellular response to aminoglycoside-induced mistranslation, we used a whole-genome microarray analysis of geneticin-treated versus untreated cells, which revealed a broad transcriptional response totaling 705 genes. comparison of four geneticin treated biological replicates with four untreated biological replicates (selected for a fold change > 1.2, Benjamini-Hochberg corrected p-value < 0.05)
DDIT4 DOWN in '16 micromolar; geneticin' vs 'none'
BAG3 UP in '16 micromolar; geneticin' vs 'none'
BEST1 DOWN in '16 micromolar; geneticin' vs 'none'
ATF7IP2 UP in '16 micromolar; geneticin' vs 'none'
DNAJB11 UP in '16 micromolar; geneticin' vs 'none'
ALDH1L2 DOWN in '16 micromolar; geneticin' vs 'none'
DNAJC3 UP in '16 micromolar; geneticin' vs 'none'
HSPA1A UP in '16 micromolar; geneticin' vs 'none'
HSPA1L UP in '16 micromolar; geneticin' vs 'none'
DNAJB4 UP in '16 micromolar; geneticin' vs 'none'
CANX UP in '16 micromolar; geneticin' vs 'none'
ARNTL UP in '16 micromolar; geneticin' vs 'none'
STX1A UP in '16 micromolar; geneticin' vs 'none'
DNAJB1 UP in '16 micromolar; geneticin' vs 'none'
HSPE1P6 UP in '16 micromolar; geneticin' vs 'none'
SART3 UP in '16 micromolar; geneticin' vs 'none'
NDUFAF1 UP in '16 micromolar; geneticin' vs 'none'
OVGP1 UP in '16 micromolar; geneticin' vs 'none'
HFM1 DOWN in '16 micromolar; geneticin' vs 'none'
PDIA4 UP in '16 micromolar; geneticin' vs 'none'
NUPR1 DOWN in '16 micromolar; geneticin' vs 'none'
NDUFB6 UP in '16 micromolar; geneticin' vs 'none'
TMEM31 UP in '16 micromolar; geneticin' vs 'none'
ISYNA1 DOWN in '16 micromolar; geneticin' vs 'none'
SLITRK3 UP in '16 micromolar; geneticin' vs 'none'
CHORDC1 UP in '16 micromolar; geneticin' vs 'none'
Analysis of '16 micromolar; geneticin' vs 'none'
SLC6A9 DOWN in '16 micromolar; geneticin' vs 'none'
LRRC39 UP in '16 micromolar; geneticin' vs 'none'
RSRC2 UP in '16 micromolar; geneticin' vs 'none'
HERPUD1 UP in '16 micromolar; geneticin' vs 'none'
CCDC101 DOWN in '16 micromolar; geneticin' vs 'none'
SERPINF1 DOWN in '16 micromolar; geneticin' vs 'none'
HSPH1 UP in '16 micromolar; geneticin' vs 'none'