Tfcp2l1 UP in 'HDAC1 knock out' vs 'wild type'
Nsdhl UP in 'HDAC1 knock out' vs 'wild type'
Tuba3a UP in 'HDAC1 knock out' vs 'wild type'
Tfpi UP in 'HDAC1 knock out' vs 'wild type'
(Assay) wild_type_embryonic_stem cells_biological_rep3
wild_type_embryonic_stem cells_biological_rep3
Histone deacetylase 1 (HDAC1) is an enzyme that promotes deacetylation of acetylated lysine residues in histones and other proteins. Histone acetylation is often associated with gene activation and expression. Los of HDAC1 leads to severe problems in development and proliferation. Moreover, it seems to be the major histone deacetylase in mouse embryonic stem cells. We used microarrays to identify putative HDAC1 target genes. Experiment Overall Design: Wild type and HDAC1 mouse embryonic stem cell, originating from same litter, were used for RNA extraction and hybridization on Affymetrix microarrays.
Tbx3 UP in 'HDAC1 knock out' vs 'wild type'
Nid2 UP in 'HDAC1 knock out' vs 'wild type'
Mapt UP in 'HDAC1 knock out' vs 'wild type'
Cdkn1c DOWN in 'HDAC1 knock out' vs 'wild type'
Ina DOWN in 'HDAC1 knock out' vs 'wild type'
(Assay) wild_type_embryonic_stem cells_biological_rep2
wild_type_embryonic_stem cells_biological_rep2
Tagln DOWN in 'HDAC1 knock out' vs 'wild type'
Ctgf DOWN in 'HDAC1 knock out' vs 'wild type'
Peg3 UP in 'HDAC1 knock out' vs 'wild type'
Grb10 DOWN in 'HDAC1 knock out' vs 'wild type'
Rhox5 UP in 'HDAC1 knock out' vs 'wild type'
Htra1 UP in 'HDAC1 knock out' vs 'wild type'
Bex1 UP in 'HDAC1 knock out' vs 'wild type'
Phlda2 DOWN in 'HDAC1 knock out' vs 'wild type'
Spg21 UP in 'HDAC1 knock out' vs 'wild type'
Acta2 DOWN in 'HDAC1 knock out' vs 'wild type'
(Factor value) GENOTYPE/wild type genotype
Ddx3y DOWN in 'HDAC1 knock out' vs 'wild type'
Dusp9 UP in 'HDAC1 knock out' vs 'wild type'
Mt2 UP in 'HDAC1 knock out' vs 'wild type'
Calcoco2 UP in 'HDAC1 knock out' vs 'wild type'
Klf4 UP in 'HDAC1 knock out' vs 'wild type'
Gjb3 UP in 'HDAC1 knock out' vs 'wild type'
Wfdc2 UP in 'HDAC1 knock out' vs 'wild type'
Mt1 UP in 'HDAC1 knock out' vs 'wild type'
Wdr45 UP in 'HDAC1 knock out' vs 'wild type'
Ak4 UP in 'HDAC1 knock out' vs 'wild type'
Dusp6 DOWN in 'HDAC1 knock out' vs 'wild type'
Gm27251 UP in 'HDAC1 knock out' vs 'wild type'
Ebp UP in 'HDAC1 knock out' vs 'wild type'
Igf2 DOWN in 'HDAC1 knock out' vs 'wild type'
(Assay) HDAC1_knock_out_embryonic_stem_cells_biological_rep2
(Assay) HDAC1_knock_out_embryonic_stem_cells_biological_rep3
(Assay) HDAC1_knock_out_embryonic_stem_cells_biological_rep1
Pfkp UP in 'HDAC1 knock out' vs 'wild type'
Dnmt3a DOWN in 'HDAC1 knock out' vs 'wild type'
Ddx19b UP in 'HDAC1 knock out' vs 'wild type'
Gja1 DOWN in 'HDAC1 knock out' vs 'wild type'
H19 UP in 'HDAC1 knock out' vs 'wild type'
(Assay) wild_type_embryonic_stem cells_biological_rep1
wild_type_embryonic_stem cells_biological_rep1
Sox11 DOWN in 'HDAC1 knock out' vs 'wild type'
Emb DOWN in 'HDAC1 knock out' vs 'wild type'
Eif2s3y DOWN in 'HDAC1 knock out' vs 'wild type'
Tex19.1 UP in 'HDAC1 knock out' vs 'wild type'
Analysis of 'HDAC1 knock out' vs 'wild type'
Dsg2 UP in 'HDAC1 knock out' vs 'wild type'
(Sample) genetic modification/gene knock out