PRSS23
type: EnsemblDatabaseReference

(Assay) GSM1329618
type: Assay
has participant: A-AFFY-44

CLIC3
type: EnsemblDatabaseReference

(Assay) GSM1329622
type: Assay
has participant: A-AFFY-44

CLIC3
type: EnsemblDatabaseReference

GNLY
type: EnsemblDatabaseReference

GNLY
type: EnsemblDatabaseReference

212070_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329636
type: Assay
has participant: A-AFFY-44

226279_at
type: EFO_0005072
part of: A-AFFY-44

S1PR5
type: EnsemblDatabaseReference

(Sample) cell type/primary peripheral blood mononuclear cell
type: EFO_0000001
property type: cell type
property value: primary peripheral blood mononuclear cell

FGFBP2 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16267328243619
p value: 0.0238493582008474
refers to: FGFBP2
refers to: 223836_at
t statistic: -4.40448995978527

(Sample) individual/control 9
type: EFO_0000001
property type: individual
property value: control 9

227394_at
type: EFO_0005072
part of: A-AFFY-44

HOPX DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00013481173375
p value: 0.0104325860423373
refers to: HOPX
refers to: 211597_s_at
t statistic: -5.63274116827327

219529_at
type: EFO_0005072
part of: A-AFFY-44

A-AFFY-44
type: EFO_0000269

(Factor value) DISEASE/type I diabetes mellitus
type: EFO_0001359
property type: DISEASE
property value: type I diabetes mellitus

FEZ1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13103603949188
p value: 0.026430055319884
refers to: FEZ1
refers to: 203562_at
t statistic: -4.29626492148424

(Sample) individual/control 8
type: EFO_0000001
property type: individual
property value: control 8

219304_s_at
type: EFO_0005072
part of: A-AFFY-44

ENPP5 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06322382717687
p value: 0.0188706327728408
refers to: ENPP5
refers to: 227803_at
t statistic: -4.57213209834285

KLRD1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20024100630077
p value: 0.0104325860423373
refers to: 210606_x_at
refers to: KLRD1
t statistic: -5.60460594102378

SPON2
type: EnsemblDatabaseReference

SPON2
type: EnsemblDatabaseReference

HLA-DQA1
type: EnsemblDatabaseReference

(Sample) individual/patient 6
type: EFO_0000001
property type: individual
property value: patient 6

HLA-DQA1
type: EnsemblDatabaseReference

37145_at
type: EFO_0005072
part of: A-AFFY-44

PRSS23
type: EnsemblDatabaseReference

207840_at
type: EFO_0005072
part of: A-AFFY-44

FGFBP2
type: EnsemblDatabaseReference

NCAM1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03961094060143
p value: 0.0360435522826184
refers to: NCAM1
refers to: 227394_at
t statistic: -4.04308331017377

(Sample) individual/control 3
type: EFO_0000001
property type: individual
property value: control 3

(Sample) individual/patient 5
type: EFO_0000001
property type: individual
property value: patient 5

(Sample) disease/normal
type: EFO_0000761
property type: disease
property value: normal

KLRD1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24896708697999
p value: 0.0104325860423373
refers to: KLRD1
refers to: 207795_s_at
t statistic: -5.66676522437774

211597_s_at
type: EFO_0005072
part of: A-AFFY-44

GZMH DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17887143228371
p value: 0.0126900061770955
refers to: 210321_at
refers to: GZMH
t statistic: -5.00285660023197

GPR56
type: EnsemblDatabaseReference

(Assay) GSM1329629
type: Assay
has participant: A-AFFY-44

GPR56
type: EnsemblDatabaseReference

GNLY DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23371415569309
p value: 0.0126900061770955
refers to: GNLY
refers to: 205495_s_at
t statistic: -5.15216658846426

(Sample) individual/patient 12
type: EFO_0000001
property type: individual
property value: patient 12

(Sample) individual/patient 1
type: EFO_0000001
property type: individual
property value: patient 1

(Sample) individual/control 1
type: EFO_0000001
property type: individual
property value: control 1

(Factor value) DISEASE/normal
type: EFO_0000761
property type: DISEASE
property value: normal

(Sample) individual/patient 7
type: EFO_0000001
property type: individual
property value: patient 7

KLRF1
type: EnsemblDatabaseReference

204103_at
type: EFO_0005072
part of: A-AFFY-44

NCAM1
type: EnsemblDatabaseReference

HLA-DQB1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -3.91782331150324
p value: 0.0215985070264956
refers to: HLA-DQB1
refers to: 209480_at
t statistic: -4.46297822440317

NCAM1
type: EnsemblDatabaseReference

NLRP2
type: EnsemblDatabaseReference

202458_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329621
type: Assay
has participant: A-AFFY-44

NLRP2
type: EnsemblDatabaseReference

CCL4
type: EnsemblDatabaseReference

C1orf21
type: EnsemblDatabaseReference

(Assay) GSM1329628
type: Assay
has participant: A-AFFY-44

CCL4
type: EnsemblDatabaseReference

C1orf21
type: EnsemblDatabaseReference

Homo sapiens
type: OBI_0100026

203562_at
type: EFO_0005072
part of: A-AFFY-44

PPP2R2B
type: EnsemblDatabaseReference

PPP2R2B
type: EnsemblDatabaseReference

213849_s_at
type: EFO_0005072
part of: A-AFFY-44

GPR56 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18392881357226
p value: 0.0207454484545932
refers to: GPR56
refers to: 212070_at
t statistic: -4.50645927729017

(Assay) GSM1329633
type: Assay
has participant: A-AFFY-44

FGFBP2
type: EnsemblDatabaseReference

210321_at
type: EFO_0005072
part of: A-AFFY-44

(Sample) individual/patient 9
type: EFO_0000001
property type: individual
property value: patient 9

(Assay) GSM1329620
type: Assay
has participant: A-AFFY-44

220646_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329626
type: Assay
has participant: A-AFFY-44

227803_at
type: EFO_0005072
part of: A-AFFY-44

GNLY DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05533405275753
p value: 0.0126900061770955
refers to: GNLY
refers to: 37145_at
t statistic: -4.95562480327759

C1orf21 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00218632339903
p value: 0.014031442445498
refers to: C1orf21
refers to: 223126_s_at
t statistic: -4.77203158980537

FEZ1
type: EnsemblDatabaseReference

CD160 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.48574087626745
p value: 0.0104325860423373
refers to: 207840_at
refers to: CD160
t statistic: -5.87657258169509

FEZ1
type: EnsemblDatabaseReference

207795_s_at
type: EFO_0005072
part of: A-AFFY-44

221690_s_at
type: EFO_0005072
part of: A-AFFY-44

PDGFD DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16846208697187
p value: 0.0126900061770955
refers to: 219304_s_at
refers to: PDGFD
t statistic: -4.95664199726114

205495_s_at
type: EFO_0005072
part of: A-AFFY-44

KLRD1
type: EnsemblDatabaseReference

HLA-DQB1
type: EnsemblDatabaseReference

CD160
type: EnsemblDatabaseReference

(Assay) GSM1329635
type: Assay
has participant: A-AFFY-44

CD160
type: EnsemblDatabaseReference

223126_s_at
type: EFO_0005072
part of: A-AFFY-44

S1PR5 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24574451046457
p value: 0.0231735754253922
refers to: 230464_at
refers to: S1PR5
t statistic: -4.42216988681457

(Assay) GSM1329619
type: Assay
has participant: A-AFFY-44

(Sample) individual/patient 8
type: EFO_0000001
property type: individual
property value: patient 8

KLRF1
type: EnsemblDatabaseReference

(Assay) GSM1329623
type: Assay
has participant: A-AFFY-44

PPP2R2B DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05022768189718
p value: 0.0148106483164825
refers to: PPP2R2B
refers to: 213849_s_at
t statistic: -4.73312923921975

(Sample) individual/control 4
type: EFO_0000001
property type: individual
property value: control 4

(Sample) individual/patient 10
type: EFO_0000001
property type: individual
property value: patient 10

ENPP5
type: EnsemblDatabaseReference

ENPP5
type: EnsemblDatabaseReference

PRSS23 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.45037721350788
p value: 0.0126900061770955
refers to: PRSS23
refers to: 226279_at
t statistic: -4.97547758423726

CLIC3 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17978457226613
p value: 0.0136530534078549
refers to: 219529_at
refers to: CLIC3
t statistic: -4.82439984201331

(Assay) GSM1329631
type: Assay
has participant: A-AFFY-44

NLRP2 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17046882229124
p value: 0.0335888811789268
refers to: NLRP2
refers to: 221690_s_at
t statistic: -4.08993266541006

218638_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329616
type: Assay
has participant: A-AFFY-44

209480_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329625
type: Assay
has participant: A-AFFY-44

(Sample) individual/control 6
type: EFO_0000001
property type: individual
property value: control 6

(Sample) individual/patient 4
type: EFO_0000001
property type: individual
property value: patient 4

(Assay) GSM1329617
type: Assay
has participant: A-AFFY-44

(Sample) individual/control 10
type: EFO_0000001
property type: individual
property value: control 10

HOPX
type: EnsemblDatabaseReference

HOPX
type: EnsemblDatabaseReference

(Sample) individual/control 5
type: EFO_0000001
property type: individual
property value: control 5

(Assay) GSM1329630
type: Assay
has participant: A-AFFY-44

GZMH
type: EnsemblDatabaseReference

GZMH
type: EnsemblDatabaseReference

(Sample) individual/control 2
type: EFO_0000001
property type: individual
property value: control 2

(Assay) GSM1329624
type: Assay
has participant: A-AFFY-44

(Assay) GSM1329627
type: Assay
has participant: A-AFFY-44

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

223836_at
type: EFO_0005072
part of: A-AFFY-44

KLRF1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0007150385763
p value: 0.0184065149165439
refers to: KLRF1
refers to: 220646_s_at
t statistic: -4.60272309181371

(Sample) disease/type I diabetes mellitus
type: EFO_0001359
property type: disease
property value: type I diabetes mellitus

PDGFD
type: EnsemblDatabaseReference

PDGFD
type: EnsemblDatabaseReference

SPON2 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24228635305559
p value: 0.0136530534078549
refers to: SPON2
refers to: 218638_s_at
t statistic: -4.85016921185593

HLA-DQB1
type: EnsemblDatabaseReference

KLRD1
type: EnsemblDatabaseReference

(Sample) individual/patient 2
type: EFO_0000001
property type: individual
property value: patient 2

210606_x_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM1329632
type: Assay
has participant: A-AFFY-44

S1PR5
type: EnsemblDatabaseReference

HLA-DQA1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -2.93569456941177
p value: 0.0222911620488905
refers to: 236203_at
refers to: HLA-DQA1
t statistic: -4.44397341435895

Analysis of 'type I diabetes mellitus' vs 'normal'
type: MicroarrayDifferentialExpressionAnalysis

CCL4 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.26614796264627
p value: 0.0109819928906074
refers to: 204103_at
refers to: CCL4
t statistic: -5.39268150647822

PRSS23 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -1.26878533270809
p value: 0.0126900061770955
refers to: PRSS23
refers to: 202458_at
t statistic: -5.08246386072285

E-GEOD-55098
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: Type 1 diabetes mellitus (T1D) is a common autoimmune disease mediated by autoimmune attack against pancreatic b cells.Dys-regualtion of the component of peripheral blood mononuclear cells (PBMCs), including T-cells and B-cells, and smaller amounts of NK cells and dendritic cells, have all been implicated in this process This study sought to identify T1D associated differently expressed genes in the peripheral blood mononuclear cell (PBMC). Peripheral blood mononuclear of newly diagnosed type1 diabetes patients and normal controls were purified by LymphoprepTm gradient purification according to the manufacturerâÂÂs instructions (Axis-Shield PoC AS, Oslo, Norway) for futher microarray analysis.

230464_at
type: EFO_0005072
part of: A-AFFY-44

213831_at
type: EFO_0005072
part of: A-AFFY-44

(Sample) individual/patient 11
type: EFO_0000001
property type: individual
property value: patient 11

(Sample) individual/patient 3
type: EFO_0000001
property type: individual
property value: patient 3

236203_at
type: EFO_0005072
part of: A-AFFY-44

HLA-DQA1 DOWN in 'type I diabetes mellitus' vs 'normal'
type: DecreasedDifferentialExpressionRatio
fold change: -4.04765063118164
p value: 0.0249387021366972
refers to: HLA-DQA1
refers to: 213831_at
t statistic: -4.36277996461323

(Assay) GSM1329634
type: Assay
has participant: A-AFFY-44

(Sample) individual/control 7
type: EFO_0000001
property type: individual
property value: control 7

(Assay) GSM1329637
type: Assay
has participant: A-AFFY-44