We performed genome-wide screening using SW480 cells with Gankyrin knockdown on an Affymetrix gene expression array to identify the transcriptional targets of Gankyrin. Transcriptional profiling with samples from SW480 cells that were infected with control or gankyrin shRNA. Two condition experiment: control shRNA (three replicates) and NFIL3 shRNA (three replicates)
RP11-669N7.2 UP in 'gankyrin shRNA' vs 'control shRNA'
NRP1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
FRY UP in 'gankyrin shRNA' vs 'control shRNA'
DHRS9 DOWN in 'gankyrin shRNA' vs 'control shRNA'
DOCK5 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MTUS1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ZDHHC2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
TLE3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ANKRD29 DOWN in 'gankyrin shRNA' vs 'control shRNA'
HOTAIR DOWN in 'gankyrin shRNA' vs 'control shRNA'
ATRX UP in 'gankyrin shRNA' vs 'control shRNA'
MUC13 UP in 'gankyrin shRNA' vs 'control shRNA'
TM2D2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CBX5 UP in 'gankyrin shRNA' vs 'control shRNA'
HPGD UP in 'gankyrin shRNA' vs 'control shRNA'
NOX1 UP in 'gankyrin shRNA' vs 'control shRNA'
RNF170 DOWN in 'gankyrin shRNA' vs 'control shRNA'
LGALS1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
GULP1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CXCL1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MAN1A1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
PROX1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CCL20 DOWN in 'gankyrin shRNA' vs 'control shRNA'
LRP12 UP in 'gankyrin shRNA' vs 'control shRNA'
RASSF10 DOWN in 'gankyrin shRNA' vs 'control shRNA'
DHRS2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ZNF185 DOWN in 'gankyrin shRNA' vs 'control shRNA'
APCDD1L-AS1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
FSCN1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
COL4A1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
WWTR1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
VCAN DOWN in 'gankyrin shRNA' vs 'control shRNA'
KYNU UP in 'gankyrin shRNA' vs 'control shRNA'
ANXA13 UP in 'gankyrin shRNA' vs 'control shRNA'
AGR3 UP in 'gankyrin shRNA' vs 'control shRNA'
AKAP12 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CNTNAP2 UP in 'gankyrin shRNA' vs 'control shRNA'
HMGA2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ST3GAL1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
VAV3 UP in 'gankyrin shRNA' vs 'control shRNA'
PKIB DOWN in 'gankyrin shRNA' vs 'control shRNA'
LAMP3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ASB9 UP in 'gankyrin shRNA' vs 'control shRNA'
SPP1 UP in 'gankyrin shRNA' vs 'control shRNA'
SLC23A1 UP in 'gankyrin shRNA' vs 'control shRNA'
PITPNC1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CLRN3 UP in 'gankyrin shRNA' vs 'control shRNA'
CPVL DOWN in 'gankyrin shRNA' vs 'control shRNA'
ALDH1A3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CLIC5 DOWN in 'gankyrin shRNA' vs 'control shRNA'
KLK10 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SERPINE2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SYNGR3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
FRMD5 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CCL22 DOWN in 'gankyrin shRNA' vs 'control shRNA'
TCEAL8 DOWN in 'gankyrin shRNA' vs 'control shRNA'
TNFAIP6 UP in 'gankyrin shRNA' vs 'control shRNA'
SERPINI1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MXRA7 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CREB3L2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SLC39A8 UP in 'gankyrin shRNA' vs 'control shRNA'
ZNF395 DOWN in 'gankyrin shRNA' vs 'control shRNA'
DDC UP in 'gankyrin shRNA' vs 'control shRNA'
HEATR3 UP in 'gankyrin shRNA' vs 'control shRNA'
NTSR1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CXCL8 DOWN in 'gankyrin shRNA' vs 'control shRNA'
KRT23 UP in 'gankyrin shRNA' vs 'control shRNA'
AKT2 UP in 'gankyrin shRNA' vs 'control shRNA'
ARHGAP6 UP in 'gankyrin shRNA' vs 'control shRNA'
STEAP4 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CLDN23 DOWN in 'gankyrin shRNA' vs 'control shRNA'
DSC2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SDCBP2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
NME4 DOWN in 'gankyrin shRNA' vs 'control shRNA'
RGCC DOWN in 'gankyrin shRNA' vs 'control shRNA'
IKBIP DOWN in 'gankyrin shRNA' vs 'control shRNA'
SEPT6 DOWN in 'gankyrin shRNA' vs 'control shRNA'
LSS UP in 'gankyrin shRNA' vs 'control shRNA'
SLCO1B3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
AADAC UP in 'gankyrin shRNA' vs 'control shRNA'
TRIM36 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MMP10 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ORAI2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
FAM134B UP in 'gankyrin shRNA' vs 'control shRNA'
TOX2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
PI3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
EMP1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SUCNR1 UP in 'gankyrin shRNA' vs 'control shRNA'
TNFRSF10D DOWN in 'gankyrin shRNA' vs 'control shRNA'
GPR137B DOWN in 'gankyrin shRNA' vs 'control shRNA'
VSIG1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CTSB DOWN in 'gankyrin shRNA' vs 'control shRNA'
AKR1B10 UP in 'gankyrin shRNA' vs 'control shRNA'
AHNAK2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ADCY9 DOWN in 'gankyrin shRNA' vs 'control shRNA'
RP11-401P9.4 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MREG DOWN in 'gankyrin shRNA' vs 'control shRNA'
ANGPT1 UP in 'gankyrin shRNA' vs 'control shRNA'
FERMT2 UP in 'gankyrin shRNA' vs 'control shRNA'
PDE9A DOWN in 'gankyrin shRNA' vs 'control shRNA'
AL133493.2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
TNFRSF11B DOWN in 'gankyrin shRNA' vs 'control shRNA'
IL32 DOWN in 'gankyrin shRNA' vs 'control shRNA'
REG4 UP in 'gankyrin shRNA' vs 'control shRNA'
NEB UP in 'gankyrin shRNA' vs 'control shRNA'
HIP1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
HGD UP in 'gankyrin shRNA' vs 'control shRNA'
SAV1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
(Factor value) RNA_INTERFERENCE/gankyrin shRNA
EMP3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
PIR UP in 'gankyrin shRNA' vs 'control shRNA'
CYB5R2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
TCN1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MTL5 DOWN in 'gankyrin shRNA' vs 'control shRNA'
HSPA1A DOWN in 'gankyrin shRNA' vs 'control shRNA'
PCSK9 UP in 'gankyrin shRNA' vs 'control shRNA'
FGL1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ARL4C DOWN in 'gankyrin shRNA' vs 'control shRNA'
FAM43A DOWN in 'gankyrin shRNA' vs 'control shRNA'
RAB7B UP in 'gankyrin shRNA' vs 'control shRNA'
POU2AF1 UP in 'gankyrin shRNA' vs 'control shRNA'
PSMD10 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ENPP2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SEMA3A DOWN in 'gankyrin shRNA' vs 'control shRNA'
FBP1 UP in 'gankyrin shRNA' vs 'control shRNA'
Analysis of 'gankyrin shRNA' vs 'control shRNA'
FAM169A DOWN in 'gankyrin shRNA' vs 'control shRNA'
FAM13A UP in 'gankyrin shRNA' vs 'control shRNA'
CLDN1 UP in 'gankyrin shRNA' vs 'control shRNA'
CXCL2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
FANCD2 UP in 'gankyrin shRNA' vs 'control shRNA'
IRS2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
HMGCS2 UP in 'gankyrin shRNA' vs 'control shRNA'
CD200 UP in 'gankyrin shRNA' vs 'control shRNA'
ZNF252P UP in 'gankyrin shRNA' vs 'control shRNA'
(Factor value) RNA_INTERFERENCE/control shRNA
LCN2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CST1 UP in 'gankyrin shRNA' vs 'control shRNA'
CEACAM5 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SMOC2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SOCS2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
BICD1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
SPRR1A DOWN in 'gankyrin shRNA' vs 'control shRNA'
OPTN DOWN in 'gankyrin shRNA' vs 'control shRNA'
DNAJC6 DOWN in 'gankyrin shRNA' vs 'control shRNA'
ACOT4 DOWN in 'gankyrin shRNA' vs 'control shRNA'
BMP2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CDKN1C DOWN in 'gankyrin shRNA' vs 'control shRNA'
CDC45 UP in 'gankyrin shRNA' vs 'control shRNA'
CSRP2 DOWN in 'gankyrin shRNA' vs 'control shRNA'
PLTP DOWN in 'gankyrin shRNA' vs 'control shRNA'
CTHRC1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
MATN2 UP in 'gankyrin shRNA' vs 'control shRNA'
SOCS3 DOWN in 'gankyrin shRNA' vs 'control shRNA'
DUSP4 DOWN in 'gankyrin shRNA' vs 'control shRNA'
CCND1 DOWN in 'gankyrin shRNA' vs 'control shRNA'
PPAPDC1B DOWN in 'gankyrin shRNA' vs 'control shRNA'
LRRC19 UP in 'gankyrin shRNA' vs 'control shRNA'