Muc12Ea DOWN in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
CG4962 DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
Jon65Aiii UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
slbo DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
betaTry UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG8628 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
pst UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
CG5804 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG13323 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Pebp1 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG13482 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Jon25Biii UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
Cell migration contributes to normal development and homeostasis as well as to pathological processes such as inflammation and tumor metastasis. Previous genetic screens have revealed a few major signaling pathways that govern follicle cell migrations in the Drosophila ovary, several of which elicit transcriptional responses. However few downstream targets of the critical transcriptional regulators, such as the C/EBP homolog SLBO, have been identified. To characterize the gene expression profile of two migratory cell populations and identify SLBO targets, we employed a magnetic bead based cell separation approach to purify border cells and centripetal cells expressing the mouse CD8 antigen, and carried out whole genome microarray analysis. Experiment Overall Design: 12 samples were analyzed to compare gene expression between different cell types or gene types. Three biological repeats were done for each experiments.
(Factor value) GENOTYPE/wild type genotype
CHKov1 DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
Kmn1 UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
CG10444 DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG12057 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG18180 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG12374 UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
Jon25Bii UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
CG18180 UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
Jon25Bi UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Bace UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
(Sample) organism/Drosophila melanogaster
neo UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Jon25Biii UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG5506 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG10911 UP in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
Analysis of 'slbo mutant' vs 'wild type' in 'non-migratory cell'
Jon25Bii UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Rala DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG10911 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Analysis of 'slbo mutant' vs 'wild type' in 'migratory cell'
NT5E-2 DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
NT5E-2 DOWN in 'slbo mutant' vs 'wild type' in 'non-migratory cell'
CG12374 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Pepck UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG9466 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG5973 DOWN in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG8997 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
alphaTry UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
Cyp6a13 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
(Factor value) CELL_TYPE/non-migratory cell
Mal-A1 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG9468 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG2930 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'
CG13315 UP in 'slbo mutant' vs 'wild type' in 'migratory cell'