GRB10 DOWN in 'RNF43 siRNA' vs 'control'
TMEM245 UP in 'RNF43 siRNA' vs 'control'
TBC1D8B DOWN in 'RNF43 siRNA' vs 'control'
G3BP2 DOWN in 'RNF43 siRNA' vs 'control'
CASP7 DOWN in 'RNF43 siRNA' vs 'control'
HIST1H2AC DOWN in 'RNF43 siRNA' vs 'control'
FAM133A DOWN in 'RNF43 siRNA' vs 'control'
It has been demonstrated that Ring finger protein 43 (RNF43) is overexpressed in colorectal cancer and mediates cancer cell proliferation. We found that RNF43 was frequently overexpressed in HCC, and knockdown of RNF43 could induce apoptosis and inhibit proliferation, invasion, colony formation and xenograft growth of HCC cells. Suggesting that RNF43 is involved in tumorigenesis and progression of HCC. We used microarrays to profile gene expression patterns before and after RNF43 knockdown, and identified differentially expressed genes during this process. HepG2 cells were transfected with RNF43 siRNA or negative control siRNA in triplicate. Forty-eight hours after transfection, total RNA was extracted,labeled and hybridized to HG-U133 Plus 2.0 arrays.
COL3A1 DOWN in 'RNF43 siRNA' vs 'control'
SLC33A1 DOWN in 'RNF43 siRNA' vs 'control'
BICD2 DOWN in 'RNF43 siRNA' vs 'control'
LINC01021 DOWN in 'RNF43 siRNA' vs 'control'
CYP1B1 DOWN in 'RNF43 siRNA' vs 'control'
LINC00520 DOWN in 'RNF43 siRNA' vs 'control'
HIST1H2AD DOWN in 'RNF43 siRNA' vs 'control'
GANAB DOWN in 'RNF43 siRNA' vs 'control'
SERPINE2 DOWN in 'RNF43 siRNA' vs 'control'
FAM105A UP in 'RNF43 siRNA' vs 'control'
HIST1H3D DOWN in 'RNF43 siRNA' vs 'control'
SEC24D DOWN in 'RNF43 siRNA' vs 'control'
ZNF883 DOWN in 'RNF43 siRNA' vs 'control'
LOXL1-AS1 UP in 'RNF43 siRNA' vs 'control'
ANKRD46 UP in 'RNF43 siRNA' vs 'control'
RP11-171I2.4 DOWN in 'RNF43 siRNA' vs 'control'
FAM101B UP in 'RNF43 siRNA' vs 'control'
ZNF616 DOWN in 'RNF43 siRNA' vs 'control'
IL1R1 DOWN in 'RNF43 siRNA' vs 'control'
FKBP14 DOWN in 'RNF43 siRNA' vs 'control'
SLC6A15 UP in 'RNF43 siRNA' vs 'control'
ST3GAL6 DOWN in 'RNF43 siRNA' vs 'control'
MTHFD2L UP in 'RNF43 siRNA' vs 'control'
HIST1H2BD DOWN in 'RNF43 siRNA' vs 'control'
BLCAP DOWN in 'RNF43 siRNA' vs 'control'
HIST1H4H DOWN in 'RNF43 siRNA' vs 'control'
FAM114A1 DOWN in 'RNF43 siRNA' vs 'control'
RP11-421L21.3 DOWN in 'RNF43 siRNA' vs 'control'
LINC01234 DOWN in 'RNF43 siRNA' vs 'control'
CXCL1 DOWN in 'RNF43 siRNA' vs 'control'
TNFAIP8 UP in 'RNF43 siRNA' vs 'control'
SLC39A11 DOWN in 'RNF43 siRNA' vs 'control'
ZKSCAN1 DOWN in 'RNF43 siRNA' vs 'control'
ZNF702P DOWN in 'RNF43 siRNA' vs 'control'
IKBIP DOWN in 'RNF43 siRNA' vs 'control'
ZNF585B DOWN in 'RNF43 siRNA' vs 'control'
DZIP3 DOWN in 'RNF43 siRNA' vs 'control'
RP11-111M22.3 DOWN in 'RNF43 siRNA' vs 'control'
RSPO3 DOWN in 'RNF43 siRNA' vs 'control'
CXCL8 DOWN in 'RNF43 siRNA' vs 'control'
ZDHHC20 UP in 'RNF43 siRNA' vs 'control'
ALDH1L2 DOWN in 'RNF43 siRNA' vs 'control'
CTC-471J1.2 DOWN in 'RNF43 siRNA' vs 'control'
KIAA1024 DOWN in 'RNF43 siRNA' vs 'control'
DDHD1 DOWN in 'RNF43 siRNA' vs 'control'
PCDH7 DOWN in 'RNF43 siRNA' vs 'control'
COL5A1 DOWN in 'RNF43 siRNA' vs 'control'
TMEM30A DOWN in 'RNF43 siRNA' vs 'control'
DCBLD2 DOWN in 'RNF43 siRNA' vs 'control'
SLC35F2 UP in 'RNF43 siRNA' vs 'control'
CDC42SE2 UP in 'RNF43 siRNA' vs 'control'
PRSS23 DOWN in 'RNF43 siRNA' vs 'control'
(Factor value) RNA_INTERFERENCE/RNF43 siRNA
SLC44A3 UP in 'RNF43 siRNA' vs 'control'
ZSCAN5A DOWN in 'RNF43 siRNA' vs 'control'
ACTA2 DOWN in 'RNF43 siRNA' vs 'control'
C10orf54 UP in 'RNF43 siRNA' vs 'control'
RP11-145M9.4 UP in 'RNF43 siRNA' vs 'control'
ZNF468 DOWN in 'RNF43 siRNA' vs 'control'
MESDC2 DOWN in 'RNF43 siRNA' vs 'control'
SLC35D2 UP in 'RNF43 siRNA' vs 'control'
BICD1 DOWN in 'RNF43 siRNA' vs 'control'
CDK14 DOWN in 'RNF43 siRNA' vs 'control'
CCDC176 DOWN in 'RNF43 siRNA' vs 'control'
PPP2R1B UP in 'RNF43 siRNA' vs 'control'
RARRES2 UP in 'RNF43 siRNA' vs 'control'
ACTG2 DOWN in 'RNF43 siRNA' vs 'control'
IFI44L DOWN in 'RNF43 siRNA' vs 'control'
FLRT3 DOWN in 'RNF43 siRNA' vs 'control'
PDGFRL DOWN in 'RNF43 siRNA' vs 'control'
FAM173B DOWN in 'RNF43 siRNA' vs 'control'
PPP2R5E UP in 'RNF43 siRNA' vs 'control'
C11orf58 UP in 'RNF43 siRNA' vs 'control'