SERPINA1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LIPC UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LEPROT UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SESN3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PXDN UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DUSP5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ADD2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
STC2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SMAD3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
INHBE UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HDAC9 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ZBED2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KCNK2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BHLHE40 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ZFHX4-AS1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CXCL1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RBMS2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CAV2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SPAG4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GPX8 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
COL4A6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NMNAT2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HELLS DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PELI2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RXFP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PLEKHH2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MYH10 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CTSB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SPRY4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ICAM1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FANCI DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
NCOA3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CCDC6 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PCDH7 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RPS6KA3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GNAL DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC6A12 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CDC42BPA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GDF11 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
LETM2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SOD3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ETV5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TNF UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LINC00113 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TNFRSF11B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
QSOX1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ANGPTL2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ST3GAL1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IL15 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
UACA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
WDR26 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
COQ3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ELFN1-AS1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MALAT1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LINC00961 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LINC00312 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FLRT3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
OSMR UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HEY2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MACROD2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CTIF UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GPR110 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NT5E UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CXCL2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FKBP11 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PTAFR UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
COL4A5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EFEMP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TKT DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PDGFB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC46A3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RFTN1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PPFIA4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RBBP9 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
NEAT1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DCDC2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TMPRSS3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CCDC153 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ATF3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ETV4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
OPRK1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KAL1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AP3B2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HRCT1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TGM2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TNFRSF19 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ETV1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FAM43A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DUSP6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LYPD6 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
FOXA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FAM107A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MMP10 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EBI3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MT1X DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
TTPA DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
S100A2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CCDC126 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FRMD5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TENM3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BMPR1B DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
UCMA DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
KIT DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CPAMD8 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FGFBP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ARHGEF39 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC7A11 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PLCG2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PCP4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EXT1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CLIC5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SEC14L1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PPARGC1A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EGR1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SYBU DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
STC1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MUC16 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LTB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SEMA6A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC8A1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PDE4DIP UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ADRB1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC5A3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LIPG UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC2A12 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RGCC UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TLR1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CYBRD1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KIAA0513 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC24A3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DNMBP UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ACOT8 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
WIBG DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
THBS1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC6A15 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SFTPB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC39A10 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SDC2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CYP4B1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SOX5 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC44A1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FRMD4A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SIPA1L1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AC005682.5 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RHOBTB3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GNAS DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MFGE8 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PTPRE UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DNAJC6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HEXIM1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
INPP4B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PALMD UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DHRS2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
FGF18 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP11-231N3.1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CADM1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GPRC5A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SPNS2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RNF183 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FZD10 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PRKAA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MT1H DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CP UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ENO2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PSRC1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
NLRP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EPHB1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ADM UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KCNT2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AK7 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CAMK2N1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TIMP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LINC00963 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MACC1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
QPCT UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RASL10A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AKAP12 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GUCY1B3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
UPK1B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AXIN2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ANTXR1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MALL UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GBP3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CNTNAP2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MIR210HG UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SYK DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CD200 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CBLB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DUSP4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GNMT DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MARC1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PRRT3-AS1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ATRNL1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NOVA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NME8 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PROM1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NEK5 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
LSM11 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
EGFR UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RAB25 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IGSF5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AGR2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NPTXR UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HCK UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DDR2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TMED5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KIAA1244 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAB21L3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TRIB2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ITGB3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LTBP2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NCALD UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MSLN UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
S100A4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
VEPH1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AOC1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
GJB2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CDH6 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CD55 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SH3BP4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DOCK11 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC16A14 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
KCNJ6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ADAMTS1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LPAR3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
C1orf43 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RAMP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GAL DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RPS6KA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IGFBP3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SCEL UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NUPR1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KCNE3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
FAS DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
XK DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MT1F DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CACNA2D3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SNCA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC34A2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MCOLN2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PABPC1L UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NPAS3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PLAU UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TNFRSF12A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SNX9 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BORA DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ORAOV1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CLIP4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TXNRD1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CTGF UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CD69 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CAV1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KLK10 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CHN2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GJB6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
QPRT UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KIAA0247 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PARD3B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAATS1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
ZNF462 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SLC14A2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAFF UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ZMAT3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FAM129A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DIRAS2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
XDH UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
S100A14 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CNTN1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SMOC2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IGF1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IER5L UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KCNJ3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
METTL7A DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
NEK3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
COL8A1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DRAM1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GPNMB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CNTN4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CLSTN2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CLDN16 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ERO1LB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
TNC UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PLAT UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
VEGFA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DTNA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PBX1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PTGER2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
DAPP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
IL6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
(Factor value) COMPOUND/recombinant human MFAP5 protein 200
CAPN9 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NNMT UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
Analysis of 'recombinant human MFAP5 protein' vs 'vehicle control'
UNC5B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PRKCA UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ABCA4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GDF15 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RAB39B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RAB27A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CD47 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ITIH5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AC109642.1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RBM24 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LINC01503 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FMO2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP11-391M1.4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AC005083.1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AJAP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
JUN UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PNMA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CYR61 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RASL11A DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
PDE7B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
C6orf223 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NTF3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
KIF20A DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
TMEM100 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
FAM132B UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CXCL14 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ISG20 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
HKDC1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ARHGAP24 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LGALS14 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ARL4C UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP6-201G10.2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
INHBB UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
NDRG1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAP2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
FRY UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AC017002.2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PDXK UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CDC25C DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAST4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ATP7B DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
GLS2 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
UGCG UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PHEX UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RNF182 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
CDH18 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RBMS3 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PROS1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP1-153G14.4 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SCGB1A1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
FABP6 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MT2A DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
AADACP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PCDH19 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
ETS1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PCOLCE UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RRAGD UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RGS20 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SGIP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
EMP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
Ovarian cancer is the fifth most common form of cancer in women in the United States. Among different types of ovarian cancer, epithelial ovarian cancer is the most common and is highly lethal, however, prognostic and predictive markers, which can be used to predict chemoresponse and patient survival, have not been thoroughly explored. One critically important yet often overlooked component to the tumor progression process is the tumor microenvironment. Primarily composed of fibroblasts and extracellular matrix proteins (ECM) as well as endothelial cells and lymphocytic infiltrate, the tumor microenvironment has been shown to directly affect cell growth, migration, and differentiation through secreted proteins, cell-cell interactions and matrix remodeling (Tlsty and Coussens, 2006). The tumor microenvironment has the potential to promote tumor initiation of normal epithelial cells and facilitate progression of malignant cells, thereby, presenting a unique approach to diagnosing, understanding and treating cancer. Using a whole-genome oligonucleotide array platform to perform transcriptome profiling on the fibroblastic stromal component microdissected from a series of advanced stage high-grade serous ovarian adenocarcinomas, we identified a transcriptome signature for the ovarian cancer associated fibroblast (CAF). We further functionally characterized one of the identified genes, MFAP5, and we showed that stromal MFAP5 is a prognostic marker associated with poor patient survival. In addition to that, to investigate the signaling machanism and the effect of MFAP5 treatment on ovarian cancer cells, transcriptome profiling of MFAP5 treated OVCA432 high-grade serous ovarian cancer cells was performed. Further functional studies showed that stromal MFAP5 modulated ovarian cancer cell motility and invasion potential. High grade serous ovarian cancer cell line OVCA432 was used. Total RNA was isolated from control samples and MFAP5 treated cancer cell samples at 48 hours post-treatment. Followed by cDNA synthesis, IVT and biotin labeling, samples were then hybridized onto Affymetrix Human genome U133 plus 2.0 microarrays. For each treatment group, three independent samples were prepared for the microarray experiment.
SCG5 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MT1E DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
DHRS3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MAMDC2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BDKRB2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
LOXL4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
GADD45A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
PRR5L DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CPT1A DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP11-364B14.3 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
SPP1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SYT11 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AHNAK2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
WNT7A UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BACH2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RARB DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
BUB1 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
RP11-283G6.4 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
BCL2L11 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
MET UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SMARCA2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
MPHOSPH6 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
TROAP DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
TRIM59 DOWN in 'recombinant human MFAP5 protein' vs 'vehicle control'
CHAC1 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
AKAP6 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
SEMA3C UP in 'recombinant human MFAP5 protein' vs 'vehicle control'
RIN2 UP in 'recombinant human MFAP5 protein' vs 'vehicle control'