AW495222 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 6.81709584261788E-5
refers to: AW495222
refers to: 1444259_at
t statistic: 6.17859974662559

1443287_at
type: EFO_0005072
part of: A-AFFY-45

1422580_at
type: EFO_0005072
part of: A-AFFY-45

Ptgs2
type: EnsemblDatabaseReference

1420352_at
type: EFO_0005072
part of: A-AFFY-45

1419066_at
type: EFO_0005072
part of: A-AFFY-45

(Factor value) GENOTYPE/wild type genotype
type: EFO_0000001
property type: GENOTYPE
property value: wild type genotype

Arpp21 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.21544720978715E-8
refers to: 1451280_at
refers to: Arpp21
t statistic: -12.0158628312047

Tex40 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 5.48625679188474E-9
refers to: Tex40
refers to: 1449074_at
t statistic: -12.7801484381462

Tulp4
type: EnsemblDatabaseReference

(Sample) sex/female
type: EFO_0001265
property type: sex
property value: female

Fam19a1
type: EnsemblDatabaseReference

Fzd3
type: EnsemblDatabaseReference

Lgr5 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 0.0159002071393492
refers to: 1450988_at
refers to: Lgr5
t statistic: 4.83770279967422

(Sample) strain/CBA X C57Bl/6
type: EFO_0000001
property type: strain
property value: CBA X C57Bl/6

Fst
type: EnsemblDatabaseReference

Tpx2
type: EnsemblDatabaseReference

Nsg2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 0.0019208379883626
refers to: 1456685_at
refers to: Nsg2
t statistic: 4.23490649712598

Sostdc1
type: EnsemblDatabaseReference

Ppp1r1b
type: EnsemblDatabaseReference

Plk5 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.81973550392691E-11
refers to: Plk5
refers to: 1434984_at
t statistic: -21.7462702902737

(Assay) GSM936856
type: Assay
has participant: A-AFFY-45

Eomes UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.0304063678313465
refers to: Eomes
refers to: 1426001_at
t statistic: 4.12546105943537

Pttg1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8
p value: 0.0420272461708398
refers to: 1424105_a_at
refers to: Pttg1
t statistic: 2.63699927856272

Myo7a UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.042102054305895
refers to: 1421385_a_at
refers to: Myo7a
t statistic: 3.71960641707803

Myh7 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7
p value: 2.17175313671608E-8
refers to: Myh7
refers to: 1448553_at
t statistic: -11.5168778863678

Rgs4 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 6.21630015394602E-9
refers to: Rgs4
refers to: 1416287_at
t statistic: -13.3980240090841

1452959_a_at
type: EFO_0005072
part of: A-AFFY-45

1430442_at
type: EFO_0005072
part of: A-AFFY-45

Gabrd
type: EnsemblDatabaseReference

Cnksr2
type: EnsemblDatabaseReference

Pde10a DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.78588369215271E-6
refers to: 1419389_at
refers to: Pde10a
t statistic: -7.8649978379855

Dmrt2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 5.27559645794755E-8
refers to: 1426867_at
refers to: Dmrt2
t statistic: 11.3607890329366

Nos1ap
type: EnsemblDatabaseReference

1426867_at
type: EFO_0005072
part of: A-AFFY-45

Mid1
type: EnsemblDatabaseReference

1449074_at
type: EFO_0005072
part of: A-AFFY-45

Eomes
type: EnsemblDatabaseReference

1435172_at
type: EFO_0005072
part of: A-AFFY-45

1455452_x_at
type: EFO_0005072
part of: A-AFFY-45

Prps1l3
type: EnsemblDatabaseReference

A330076H08Rik DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 5.08128662454898E-4
refers to: A330076H08Rik
refers to: 1457557_at
t statistic: -4.9161566858458

Gm12300
type: EnsemblDatabaseReference

Prps1l3 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 1.61847053567975E-11
refers to: 1454814_s_at
refers to: Prps1l3
t statistic: 19.4640660099407

1440032_at
type: EFO_0005072
part of: A-AFFY-45

1420419_a_at
type: EFO_0005072
part of: A-AFFY-45

1427072_at
type: EFO_0005072
part of: A-AFFY-45

1457336_at
type: EFO_0005072
part of: A-AFFY-45

1457984_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936866
type: Assay
has participant: A-AFFY-45

(Assay) GSM936855
type: Assay
has participant: A-AFFY-45

1440282_at
type: EFO_0005072
part of: A-AFFY-45

Cplx3
type: EnsemblDatabaseReference

Ano3
type: EnsemblDatabaseReference

Nptx2
type: EnsemblDatabaseReference

Brca1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 1.12209486077075E-7
refers to: Brca1
refers to: 1424629_at
t statistic: 10.6811477998254

1438884_at
type: EFO_0005072
part of: A-AFFY-45

9230110C19Rik
type: EnsemblDatabaseReference

Lemd1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 2.18283223908825E-6
refers to: 1445642_at
refers to: Lemd1
t statistic: -8.38938523567117

Vps37a
type: EnsemblDatabaseReference

1443934_at
type: EFO_0005072
part of: A-AFFY-45

Ifit1
type: EnsemblDatabaseReference

Nsg2
type: EnsemblDatabaseReference

Pdyn
type: EnsemblDatabaseReference

(Assay) GSM936860
type: Assay
has participant: A-AFFY-45

Penk
type: EnsemblDatabaseReference

Brca1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 5.7180122435513E-9
refers to: Brca1
refers to: 1424629_at
t statistic: 12.7360091672501

(Sample) genotype/HDAC4het
type: EFO_0000001
property type: genotype
property value: HDAC4het

1810022K09Rik
type: EnsemblDatabaseReference

Gfra2
type: EnsemblDatabaseReference

Rgs4 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.48062285459976E-9
refers to: 1448285_at
refers to: Rgs4
t statistic: -14.8792600077642

1451280_at
type: EFO_0005072
part of: A-AFFY-45

1418188_a_at
type: EFO_0005072
part of: A-AFFY-45

1451331_at
type: EFO_0005072
part of: A-AFFY-45

1425545_x_at
type: EFO_0005072
part of: A-AFFY-45

Nfya
type: EnsemblDatabaseReference

A330076H08Rik
type: EnsemblDatabaseReference

1429668_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936859
type: Assay
has participant: A-AFFY-45

Qk
type: EnsemblDatabaseReference

1423415_at
type: EFO_0005072
part of: A-AFFY-45

1450839_at
type: EFO_0005072
part of: A-AFFY-45

Abi3bp
type: EnsemblDatabaseReference

Gpr83
type: EnsemblDatabaseReference

Rspo1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.2598229884428E-6
refers to: 1449319_at
refers to: Rspo1
t statistic: -7.65177895493312

Rasl10a
type: EnsemblDatabaseReference

Lamp5
type: EnsemblDatabaseReference

Slc1a2
type: EnsemblDatabaseReference

Penk DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 5.09763236494212E-7
refers to: Penk
refers to: 1427038_at
t statistic: -9.4528554342149

Gpr83 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.30257236380891E-11
refers to: Gpr83
refers to: 1423415_at
t statistic: -20.7446489940065

Ddit4l DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 6.68985501460142E-9
refers to: Ddit4l
refers to: 1439332_at
t statistic: -12.5863522671504

Lemd1
type: EnsemblDatabaseReference

Myh7
type: EnsemblDatabaseReference

1429363_at
type: EFO_0005072
part of: A-AFFY-45

Arpp19
type: EnsemblDatabaseReference

1459377_at
type: EFO_0005072
part of: A-AFFY-45

1438239_at
type: EFO_0005072
part of: A-AFFY-45

Tnfrsf25
type: EnsemblDatabaseReference

Ptpn20
type: EnsemblDatabaseReference

Rgs13
type: EnsemblDatabaseReference

1449980_a_at
type: EFO_0005072
part of: A-AFFY-45

Otof
type: EnsemblDatabaseReference

1419389_at
type: EFO_0005072
part of: A-AFFY-45

Stard8 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.37318710425882E-9
refers to: Stard8
refers to: 1427072_at
t statistic: -13.2040413427887

Pbx3 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.0427776534485519
refers to: Pbx3
refers to: 1447640_s_at
t statistic: 3.65005846523952

Sfmbt2
type: EnsemblDatabaseReference

RP24-439I22.1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 1.35711463752571E-7
refers to: RP24-439I22.1
refers to: 1455087_at
t statistic: 10.0204958859432

Stard8
type: EnsemblDatabaseReference

Ifit1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.9860937163786E-4
refers to: Ifit1
refers to: 1450783_at
t statistic: 5.57308325794367

1427038_at
type: EFO_0005072
part of: A-AFFY-45

Scn9a
type: EnsemblDatabaseReference

Hfe2
type: EnsemblDatabaseReference

Phka2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.2635491097367E-6
refers to: Phka2
refers to: 1437941_at
t statistic: -8.38771109299704

Gm26917
type: EnsemblDatabaseReference

Ankrd63
type: EnsemblDatabaseReference

Ryr1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 8.05052183520425E-11
refers to: Ryr1
refers to: 1427306_at
t statistic: -18.7368593717273

1426278_at
type: EFO_0005072
part of: A-AFFY-45

Cartpt DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 2.16552948834752E-6
refers to: Cartpt
refers to: 1422825_at
t statistic: -8.3973312134655

Scn4b DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 2.01745816993459E-9
refers to: Scn4b
refers to: 1434008_at
t statistic: -14.5937751307242

Lgr5
type: EnsemblDatabaseReference

Vps37a UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 1.01074106748412E-4
refers to: Vps37a
refers to: 1429363_at
t statistic: 5.95320270097399

1440290_at
type: EFO_0005072
part of: A-AFFY-45

Phka2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.45613907414764E-7
refers to: 1437941_at
refers to: Phka2
t statistic: -10.0455498325188

Prss22
type: EnsemblDatabaseReference

Rgs4 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.06131920085411E-8
refers to: 1448285_at
refers to: Rgs4
t statistic: -12.1678564933079

Gm12300 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 3.69596547140551E-6
refers to: 1427867_at
refers to: Gm12300
t statistic: -7.69138180726315

Gpr83 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.04479220337316E-12
refers to: Gpr83
refers to: 1423415_at
t statistic: -23.1090478184427

(Assay) GSM936843
type: Assay
has participant: A-AFFY-45

Crhbp
type: EnsemblDatabaseReference

Gm10010
type: EnsemblDatabaseReference

Npas4
type: EnsemblDatabaseReference

(Factor value) GENOTYPE/HDAC4het
type: EFO_0000001
property type: GENOTYPE
property value: HDAC4het

Npy2r
type: EnsemblDatabaseReference

Onecut2
type: EnsemblDatabaseReference

1426973_at
type: EFO_0005072
part of: A-AFFY-45

R3hdm1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 1.220344236389E-6
refers to: 1458539_at
refers to: R3hdm1
t statistic: -8.41514991599673

Ptpn20 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.73469942112146E-8
refers to: 1418759_at
refers to: Ptpn20
t statistic: 12.3369102706703

Ier5l
type: EnsemblDatabaseReference

Onecut2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 1.21426271959183E-10
refers to: Onecut2
refers to: 1440005_at
t statistic: 18.1357654723029

Plcb1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.05451966183047E-7
refers to: Plcb1
refers to: 1425600_a_at
t statistic: -8.90431204504231

Gabrd
type: EnsemblDatabaseReference

Ddit4l
type: EnsemblDatabaseReference

Itpka
type: EnsemblDatabaseReference

1420720_at
type: EFO_0005072
part of: A-AFFY-45

Ovgp1
type: EnsemblDatabaseReference

1440804_at
type: EFO_0005072
part of: A-AFFY-45

Pde10a
type: EnsemblDatabaseReference

1438390_s_at
type: EFO_0005072
part of: A-AFFY-45

Malat1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.64937194867201E-7
refers to: 1418189_s_at
refers to: Malat1
t statistic: -9.4981578425275

1425600_a_at
type: EFO_0005072
part of: A-AFFY-45

Dlgap2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.64322020406645E-7
refers to: 1439767_at
refers to: Dlgap2
t statistic: -9.26754124114324

(Sample) sex/male
type: EFO_0001266
property type: sex
property value: male

Gm12300
type: EnsemblDatabaseReference

Malat1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 3.42936068741344E-7
refers to: 1418188_a_at
refers to: Malat1
t statistic: -9.31254759993264

1439569_at
type: EFO_0005072
part of: A-AFFY-45

Npas4 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 0.00193745309462449
refers to: Npas4
refers to: 1459372_at
t statistic: -4.23073905682225

1451751_at
type: EFO_0005072
part of: A-AFFY-45

Tpx2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 6.47454291012638E-8
refers to: Tpx2
refers to: 1428105_at
t statistic: 11.163613937818

Cartpt
type: EnsemblDatabaseReference

Asap1
type: EnsemblDatabaseReference

Hfe2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 4.78155738021983E-7
refers to: 1454137_s_at
refers to: Hfe2
t statistic: -9.50695860071036

A830010M20Rik
type: EnsemblDatabaseReference

1453196_a_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936858
type: Assay
has participant: A-AFFY-45

1427351_s_at
type: EFO_0005072
part of: A-AFFY-45

Nptx2
type: EnsemblDatabaseReference

Twist1
type: EnsemblDatabaseReference

Dmkn
type: EnsemblDatabaseReference

Vip DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 8.99153453383592E-9
refers to: Vip
refers to: 1428664_at
t statistic: -12.9845509943124

Crh
type: EnsemblDatabaseReference

1444513_at
type: EFO_0005072
part of: A-AFFY-45

1440455_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936865
type: Assay
has participant: A-AFFY-45

Itpka DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.09627487751542E-10
refers to: 1424037_at
refers to: Itpka
t statistic: -18.3423944159272

Myo7a
type: EnsemblDatabaseReference

Egr2
type: EnsemblDatabaseReference

1418938_at
type: EFO_0005072
part of: A-AFFY-45

Camk4 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.01322356746906E-5
refers to: 1426167_a_at
refers to: Camk4
t statistic: -7.34197424941505

(Assay) GSM936852
type: Assay
has participant: A-AFFY-45

Th
type: EnsemblDatabaseReference

Nrep
type: EnsemblDatabaseReference

Gpr83 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.9645189312153E-12
refers to: Gpr83
refers to: 1439569_at
t statistic: -21.9098406456221

Malat1
type: EnsemblDatabaseReference

(Assay) GSM936854
type: Assay
has participant: A-AFFY-45

Ptpn20 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 3.67501552962912E-8
refers to: Ptpn20
refers to: 1418759_at
t statistic: 11.0786760613111

Tulp4
type: EnsemblDatabaseReference

Cks1b
type: EnsemblDatabaseReference

(Sample) organism/Mus musculus
type: Mus musculus
property type: organism
property value: Mus musculus

Crh DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 3.07047852607413E-11
refers to: Crh
refers to: 1457984_at
t statistic: -18.3767738825903

Fam168a
type: EnsemblDatabaseReference

Th UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.042102054305895
refers to: 1420546_at
refers to: Th
t statistic: 3.73543614583921

Zfp800
type: EnsemblDatabaseReference

Dmkn DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 2.19464625161098E-7
refers to: Dmkn
refers to: 1428781_at
t statistic: -9.63898647291747

Sostdc1
type: EnsemblDatabaseReference

Ppp1r1b
type: EnsemblDatabaseReference

1418370_at
type: EFO_0005072
part of: A-AFFY-45

Arhgap32
type: EnsemblDatabaseReference

Mid1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.0304358298492327
refers to: Mid1
refers to: 1438239_at
t statistic: -2.81610285568811

Gpr153 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 1.27496018436123E-10
refers to: 1426973_at
refers to: Gpr153
t statistic: -17.9666709168464

1437581_at
type: EFO_0005072
part of: A-AFFY-45

Dio2
type: EnsemblDatabaseReference

1417263_at
type: EFO_0005072
part of: A-AFFY-45

Nos1ap
type: EnsemblDatabaseReference

R3hdm1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.94276434500371E-6
refers to: R3hdm1
refers to: 1440032_at
t statistic: -8.09888551645444

Apc DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 1.36107524492909E-7
refers to: 1420957_at
refers to: Apc
t statistic: -10.0179871703348

Pdyn DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.2828744145636E-9
refers to: 1416266_at
refers to: Pdyn
t statistic: -13.2830950167545

Analysis of 'R6/2' vs 'wild type genotype'
type: MicroarrayDifferentialExpressionAnalysis

E-GEOD-38218
type: microarray 1colour mrna differential
RO_0002162: Mus musculus
description: Histone deacetylase (HDAC) 4 is a transcriptional repressor that contains a glutamine rich domain. We hypothesised that it may be involved in the molecular pathogenesis of Huntington's disease (HD), a protein folding neurodegenerative disorder caused by an aggregation-prone polyglutamine expansion and transcriptional dysregulation. We found that HDAC4 interacts with huntingtin in a polyglutamine-length dependent manner and co-localises with cytoplasmic inclusions. We show that HDAC4 reduction delayed cytoplasmic aggregate formation, restored Bdnf transcript levels and rescued neuronal and cortico-striatal synaptic function in HD mouse models. This was accompanied by an improvement in motor co-ordination, neurological phenotypes and increased lifespan. Surprisingly, HDAC4 reduction had no effect on global transcriptional dysfunction and did not modulate nuclear huntingtin aggregation. Our results define a crucial role for cytoplasmic aggregation in the molecular pathology of HD. HDAC4 reduction presents a novel strategy for targeting huntingtin aggregation which may be amenable to small molecule therapeutics. mRNA expression analysis was performed by microarray in 9 weeks old WT (n=9), R6/2 (n=9), HDAC4het (n=9) and Double R6/2::HDAC4het (n=10) mice. Microarray quality control was performed using the software package provided on RACE (http://race.unil.ch).
uses data from: http://identifiers.org/pubmed/24302884

Eomes
type: EnsemblDatabaseReference

Gpr83 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.21426271959183E-10
refers to: 1439569_at
refers to: Gpr83
t statistic: -18.0939035268394

1418687_at
type: EFO_0005072
part of: A-AFFY-45

Fam168a UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 0.0432564388228143
refers to: Fam168a
refers to: 1434375_at
t statistic: 3.63819942471678

Camk4
type: EnsemblDatabaseReference

Abi3bp DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.85954085501163E-6
refers to: Abi3bp
refers to: 1427054_s_at
t statistic: -8.13143399942118

Fst DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5
p value: 5.61028538675472E-9
refers to: Fst
refers to: 1434458_at
t statistic: -12.761574446128

Gm10010
type: EnsemblDatabaseReference

1454814_s_at
type: EFO_0005072
part of: A-AFFY-45

1436127_at
type: EFO_0005072
part of: A-AFFY-45

1445642_at
type: EFO_0005072
part of: A-AFFY-45

Npy2r
type: EnsemblDatabaseReference

Apc
type: EnsemblDatabaseReference

1428960_at
type: EFO_0005072
part of: A-AFFY-45

Ifit1
type: EnsemblDatabaseReference

Nsg2
type: EnsemblDatabaseReference

Sst
type: EnsemblDatabaseReference

Penk
type: EnsemblDatabaseReference

1444139_at
type: EFO_0005072
part of: A-AFFY-45

1810022K09Rik
type: EnsemblDatabaseReference

Tex40
type: EnsemblDatabaseReference

(Factor value) GENOTYPE/R6/2::HDAC4het
type: EFO_0000001
property type: GENOTYPE
property value: R6/2::HDAC4het

Dlgap2
type: EnsemblDatabaseReference

Nktr
type: EnsemblDatabaseReference

Capn10
type: EnsemblDatabaseReference

Homer1
type: EnsemblDatabaseReference

1433716_x_at
type: EFO_0005072
part of: A-AFFY-45

Kcnj9 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 0.00180110378828974
refers to: Kcnj9
refers to: 1450712_at
t statistic: -4.26819874543668

Egr2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.0
p value: 4.86292526849279E-4
refers to: 1427682_a_at
refers to: Egr2
t statistic: -4.93880607893031

Scn9a UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 3.67223719500873E-8
refers to: Scn9a
refers to: 1442810_x_at
t statistic: 11.0808426143582

A330076H08Rik
type: EnsemblDatabaseReference

Ddit4l DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 1.0224964550002E-9
refers to: Ddit4l
refers to: 1439332_at
t statistic: -15.2657377340111

Qk
type: EnsemblDatabaseReference

Ppp1r1b DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.03850096832213E-5
refers to: Ppp1r1b
refers to: 1451331_at
t statistic: -7.32664991162144

Myl4 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 8.62526775320014E-10
refers to: Myl4
refers to: 1422580_at
t statistic: -14.5986151730127

Cdhr1
type: EnsemblDatabaseReference

R3hdm1
type: EnsemblDatabaseReference

Abi3bp
type: EnsemblDatabaseReference

Gpr83
type: EnsemblDatabaseReference

A830010M20Rik
type: EnsemblDatabaseReference

1458539_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936861
type: Assay
has participant: A-AFFY-45

Gpr153 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 3.58767585893645E-10
refers to: Gpr153
refers to: 1426973_at
t statistic: -15.5079115290585

Ovgp1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.31833965783934E-8
refers to: 1426526_s_at
refers to: Ovgp1
t statistic: -10.5339412046263

Dmkn DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.21427651964441E-6
refers to: 1428781_at
refers to: Dmkn
t statistic: -8.82256527047774

Lemd1
type: EnsemblDatabaseReference

Plcb1
type: EnsemblDatabaseReference

Myh7
type: EnsemblDatabaseReference

Tnnc1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 5.03437640017034E-8
refers to: 1418370_at
refers to: Tnnc1
t statistic: -11.4063195685487

1418189_s_at
type: EFO_0005072
part of: A-AFFY-45

1424105_a_at
type: EFO_0005072
part of: A-AFFY-45

Ifi27l2a
type: EnsemblDatabaseReference

Nptx2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.60532202722475E-9
refers to: Nptx2
refers to: 1420720_at
t statistic: -13.1495801794192

Ptpn20
type: EnsemblDatabaseReference

Rgs13
type: EnsemblDatabaseReference

Pttg1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 0.0366511531884304
refers to: Pttg1
refers to: 1438390_s_at
t statistic: 2.71432454536643

1427867_at
type: EFO_0005072
part of: A-AFFY-45

1444980_at
type: EFO_0005072
part of: A-AFFY-45

Enkur
type: EnsemblDatabaseReference

Arc
type: EnsemblDatabaseReference

1438451_at
type: EFO_0005072
part of: A-AFFY-45

Pou4f1
type: EnsemblDatabaseReference

Sfmbt2
type: EnsemblDatabaseReference

RP24-439I22.1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 9.54686338246331E-7
refers to: 1455087_at
refers to: RP24-439I22.1
t statistic: 8.99328500321365

1448441_at
type: EFO_0005072
part of: A-AFFY-45

Th
type: EnsemblDatabaseReference

1427053_at
type: EFO_0005072
part of: A-AFFY-45

AW495222
type: EnsemblDatabaseReference

Scn9a
type: EnsemblDatabaseReference

Hfe2
type: EnsemblDatabaseReference

Palm2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 6.12348157738683E-4
refers to: 1459377_at
refers to: Palm2
t statistic: -4.81966657875248

Gm26917
type: EnsemblDatabaseReference

1437941_at
type: EFO_0005072
part of: A-AFFY-45

Rasl10a DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.33444323516941E-10
refers to: 1427975_at
refers to: Rasl10a
t statistic: -16.7570154766074

Nrep
type: EnsemblDatabaseReference

Onecut2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 1.89084813058974E-11
refers to: Onecut2
refers to: 1444980_at
t statistic: 21.235676677325

1436387_at
type: EFO_0005072
part of: A-AFFY-45

RP24-439I22.1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.0149271708125237
refers to: 1440557_at
refers to: RP24-439I22.1
t statistic: 3.25671623668737

1427682_a_at
type: EFO_0005072
part of: A-AFFY-45

Lgr5
type: EnsemblDatabaseReference

H2-D1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.0316122772770567
refers to: H2-D1
refers to: 1425545_x_at
t statistic: 2.79505052534856

1460044_at
type: EFO_0005072
part of: A-AFFY-45

Palm2
type: EnsemblDatabaseReference

Npy2r DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.05367693074684E-4
refers to: Npy2r
refers to: 1417489_at
t statistic: -5.38484560020482

1443612_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936849
type: Assay
has participant: A-AFFY-45

Cks1b
type: EnsemblDatabaseReference

Tnnc1
type: EnsemblDatabaseReference

(Assay) GSM936847
type: Assay
has participant: A-AFFY-45

Cks1b UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 9.53508459473493E-10
refers to: 1448441_at
refers to: Cks1b
t statistic: 14.4966880666256

Fam168a
type: EnsemblDatabaseReference

1416266_at
type: EFO_0005072
part of: A-AFFY-45

AW495222 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 1.29228627430585E-5
refers to: AW495222
refers to: 1444259_at
t statistic: 6.92486617126267

Gpr153
type: EnsemblDatabaseReference

(Sample) age/9
type: EFO_0000001
property type: age
property value: 9

Slc1a2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 9.37055176435275E-5
refers to: Slc1a2
refers to: 1439940_at
t statistic: -5.99507862290569

1449361_at
type: EFO_0005072
part of: A-AFFY-45

Nmb
type: EnsemblDatabaseReference

Ryr1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 3.38379404890959E-10
refers to: Ryr1
refers to: 1427306_at
t statistic: -15.6066100413872

1434458_at
type: EFO_0005072
part of: A-AFFY-45

Wisp1 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.01836562534754
refers to: Wisp1
refers to: 1448594_at
t statistic: 4.65137076914463

Cplx3 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.85579527812528E-10
refers to: Cplx3
refers to: 1424606_at
t statistic: -15.6392012832755

(Assay) GSM936876
type: Assay
has participant: A-AFFY-45

Onecut2
type: EnsemblDatabaseReference

Arhgap32
type: EnsemblDatabaseReference

Qk DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.23471378639422E-6
refers to: 1425597_a_at
refers to: Qk
t statistic: -8.40382088452096

RP24-439I22.1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.0149154112442438
refers to: RP24-439I22.1
refers to: 1440557_at
t statistic: 3.19371581048655

Ddit4l
type: EnsemblDatabaseReference

Phka2
type: EnsemblDatabaseReference

Malat1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 1.54235460944478E-7
refers to: Malat1
refers to: 1438403_s_at
t statistic: -9.9265619592341

Camk2n1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.8
p value: 0.00206770784526701
refers to: Camk2n1
refers to: 1440455_at
t statistic: -4.19736310162085

Egr2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.1
p value: 1.2669709495351E-4
refers to: 1427683_at
refers to: Egr2
t statistic: -5.64330137424275

(Assay) GSM936872
type: Assay
has participant: A-AFFY-45

Sfmbt2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 3.24560080008148E-10
refers to: Sfmbt2
refers to: 1434353_at
t statistic: 16.7338304557107

Myl4 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 1.0224964550002E-9
refers to: 1422580_at
refers to: Myl4
t statistic: -15.2631533620597

Shisa3 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.9
p value: 0.0281892969017821
refers to: Shisa3
refers to: 1438884_at
t statistic: 4.24366012469428

Brca1
type: EnsemblDatabaseReference

Nrep DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.80603004469249E-9
refers to: Nrep
refers to: 1450839_at
t statistic: -14.1714117706661

Npas4 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.010954724145452
refers to: Npas4
refers to: 1459372_at
t statistic: -3.42385098372652

1439332_at
type: EFO_0005072
part of: A-AFFY-45

1450712_at
type: EFO_0005072
part of: A-AFFY-45

1428781_at
type: EFO_0005072
part of: A-AFFY-45

Gm26917 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 0.00199518009720912
refers to: Gm26917
refers to: AFFX-18SRNAMur/X00686_5_at
t statistic: -4.32545749846471

1426167_a_at
type: EFO_0005072
part of: A-AFFY-45

Vip DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 7.699391816973E-10
refers to: Vip
refers to: 1428664_at
t statistic: -14.7221147849289

H2-D1
type: EnsemblDatabaseReference

Dmkn
type: EnsemblDatabaseReference

Tnfrsf25 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.58482131067594E-5
refers to: 1422231_a_at
refers to: Tnfrsf25
t statistic: -6.75705206167898

Crh
type: EnsemblDatabaseReference

1448553_at
type: EFO_0005072
part of: A-AFFY-45

Sst DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.48899983932795E-10
refers to: 1417954_at
refers to: Sst
t statistic: -17.7453977375308

Nhsl2
type: EnsemblDatabaseReference

RP24-439I22.1
type: EnsemblDatabaseReference

Homer1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 2.49069608982991E-5
refers to: Homer1
refers to: 1436387_at
t statistic: -6.7789515246262

Cnksr2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 6.05451966183047E-7
refers to: Cnksr2
refers to: 1444513_at
t statistic: -8.90420581549081

Cks1b UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 3.2828744145636E-9
refers to: Cks1b
refers to: 1416698_a_at
t statistic: 13.278015182988

Ryr1
type: EnsemblDatabaseReference

Hfe2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.37050750715809E-7
refers to: Hfe2
refers to: 1454137_s_at
t statistic: -10.0123526387018

Tex40 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.31845383363082E-7
refers to: Tex40
refers to: 1449074_at
t statistic: -10.5529667411176

Rgs13 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1
p value: 2.1174378891996E-12
refers to: Rgs13
refers to: 1442263_at
t statistic: 22.605797762106

Egr2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.0
p value: 0.00103697307096928
refers to: 1427682_a_at
refers to: Egr2
t statistic: -4.67106229025487

1447640_s_at
type: EFO_0005072
part of: A-AFFY-45

1427975_at
type: EFO_0005072
part of: A-AFFY-45

S100a5 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.6
p value: 0.0352785565925093
refers to: S100a5
refers to: 1449927_at
t statistic: 4.00370240196128

Nsg2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.0210287954391847
refers to: Nsg2
refers to: 1456685_at
t statistic: 3.06908478215854

Mus musculus
type: OBI_0100026

Tbx21 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.0364701076070709
refers to: Tbx21
refers to: 1449361_at
t statistic: 3.95037513769558

Onecut2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 2.83998708166931E-12
refers to: 1444980_at
refers to: Onecut2
t statistic: 22.1586608957899

Ifi27l2a UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 6.12685739793978E-5
refers to: 1426278_at
refers to: Ifi27l2a
t statistic: 6.2418643126725

1444259_at
type: EFO_0005072
part of: A-AFFY-45

R3hdm1
type: EnsemblDatabaseReference

Malat1
type: EnsemblDatabaseReference

Ighm
type: EnsemblDatabaseReference

Vip
type: EnsemblDatabaseReference

Twist1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 1.85781739390438E-7
refers to: Twist1
refers to: 1418733_at
t statistic: 9.77634803275942

1442263_at
type: EFO_0005072
part of: A-AFFY-45

BC030499
type: EnsemblDatabaseReference

9230110C19Rik DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.89561034463172E-8
refers to: 1443934_at
refers to: 9230110C19Rik
t statistic: -11.6394382832478

Pou4f1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8
p value: 7.94730017953568E-8
refers to: Pou4f1
refers to: 1429667_at
t statistic: 10.9776160592088

Onecut2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 2.0709217975019E-12
refers to: 1460044_at
refers to: Onecut2
t statistic: 22.917168148613

Zfp800
type: EnsemblDatabaseReference

Camkk2
type: EnsemblDatabaseReference

Malat1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.83978168248762E-8
refers to: 1452378_at
refers to: Malat1
t statistic: -11.6623374019336

(Assay) GSM936874
type: Assay
has participant: A-AFFY-45

1422609_at
type: EFO_0005072
part of: A-AFFY-45

Ryr1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 1.49761617445356E-9
refers to: 1457347_at
refers to: Ryr1
t statistic: -14.016990311327

1451931_x_at
type: EFO_0005072
part of: A-AFFY-45

Sst DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 9.68838192529938E-12
refers to: Sst
refers to: 1417954_at
t statistic: -20.1473631924938

1426001_at
type: EFO_0005072
part of: A-AFFY-45

A-AFFY-45
type: EFO_0000269

AW495222
type: EnsemblDatabaseReference

Kctd14 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 0.010961251329925
refers to: 1455452_x_at
refers to: Kctd14
t statistic: 5.19410767040478

Asap1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.14391193585539E-7
refers to: Asap1
refers to: 1425573_a_at
t statistic: -10.1645564474775

Dio2
type: EnsemblDatabaseReference

(Assay) GSM936850
type: Assay
has participant: A-AFFY-45

Tnnc1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 7.92786952263145E-8
refers to: 1418370_at
refers to: Tnnc1
t statistic: -10.4645699277422

Tbx21
type: EnsemblDatabaseReference

1450988_at
type: EFO_0005072
part of: A-AFFY-45

1460000_at
type: EFO_0005072
part of: A-AFFY-45

Pttg1
type: EnsemblDatabaseReference

Abi3bp DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 1.27007593647253E-7
refers to: Abi3bp
refers to: 1427054_s_at
t statistic: -10.5833452032142

Fam19a1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.7352389457237E-10
refers to: 1457092_at
refers to: Fam19a1
t statistic: -17.5516265668303

Camk4
type: EnsemblDatabaseReference

1418304_at
type: EFO_0005072
part of: A-AFFY-45

Gpr153
type: EnsemblDatabaseReference

1422231_a_at
type: EFO_0005072
part of: A-AFFY-45

Tpx2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 3.90650910750256E-10
refers to: Tpx2
refers to: 1428105_at
t statistic: 15.3907735478407

Dio2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.71853279536723E-7
refers to: Dio2
refers to: 1418938_at
t statistic: -9.84114624388526

(Assay) GSM936862
type: Assay
has participant: A-AFFY-45

Ryr1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 5.27559645794755E-8
refers to: 1457347_at
refers to: Ryr1
t statistic: -11.3602568199776

1424037_at
type: EFO_0005072
part of: A-AFFY-45

(Factor value) GENOTYPE/R6/2
type: EFO_0000001
property type: GENOTYPE
property value: R6/2

1425597_a_at
type: EFO_0005072
part of: A-AFFY-45

Apc
type: EnsemblDatabaseReference

Pou4f1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1
p value: 2.14555481565217E-8
refers to: 1429668_at
refers to: Pou4f1
t statistic: 12.158529536551

1429667_at
type: EFO_0005072
part of: A-AFFY-45

1444656_at
type: EFO_0005072
part of: A-AFFY-45

Enkur UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.0224964550002E-9
refers to: Enkur
refers to: 1428960_at
t statistic: 15.231923209417

Sostdc1 DOWN in 'HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 0.0433718331612379
refers to: 1449340_at
refers to: Sostdc1
t statistic: -3.61909315533168

Sst
type: EnsemblDatabaseReference

Plk5
type: EnsemblDatabaseReference

1416698_a_at
type: EFO_0005072
part of: A-AFFY-45

Analysis of 'HDAC4het' vs 'wild type genotype'
type: MicroarrayDifferentialExpressionAnalysis

Ddit4l DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5
p value: 7.2652512801019E-12
refers to: Ddit4l
refers to: 1451751_at
t statistic: -20.7107312080787

Tex40
type: EnsemblDatabaseReference

Dlgap2
type: EnsemblDatabaseReference

1439940_at
type: EFO_0005072
part of: A-AFFY-45

Nktr
type: EnsemblDatabaseReference

Capn10
type: EnsemblDatabaseReference

Homer1
type: EnsemblDatabaseReference

Ovgp1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 5.76577307121053E-8
refers to: Ovgp1
refers to: 1426526_s_at
t statistic: -11.2789779668212

Rgs4
type: EnsemblDatabaseReference

1457347_at
type: EFO_0005072
part of: A-AFFY-45

Lemd1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.31494550641184E-6
refers to: Lemd1
refers to: 1445642_at
t statistic: -8.36127915815127

Eomes UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.8
p value: 0.0267486316210759
refers to: Eomes
refers to: 1435172_at
t statistic: 4.28194521432317

Arpp21
type: EnsemblDatabaseReference

Ddit4l DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5
p value: 4.17949416057967E-11
refers to: Ddit4l
refers to: 1444139_at
t statistic: -19.7587031229382

Fst DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 1.98792006506442E-8
refers to: Fst
refers to: 1434458_at
t statistic: -12.2202937811027

Crh DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 1.26349566310867E-8
refers to: Crh
refers to: 1457984_at
t statistic: -12.6586860722626

Kctd14
type: EnsemblDatabaseReference

Shisa3 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 0.0340882575793993
refers to: 1460000_at
refers to: Shisa3
t statistic: 4.03063663724609

Prss22 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 4.73592196309916E-6
refers to: 1420352_at
refers to: Prss22
t statistic: -7.84243217767423

A830010M20Rik DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 5.37835251768082E-5
refers to: A830010M20Rik
refers to: 1438565_at
t statistic: -6.10894815911877

Cdhr1
type: EnsemblDatabaseReference

(Assay) GSM936848
type: Assay
has participant: A-AFFY-45

Scn4b
type: EnsemblDatabaseReference

1450783_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936870
type: Assay
has participant: A-AFFY-45

Rph3a
type: EnsemblDatabaseReference

(Assay) GSM936873
type: Assay
has participant: A-AFFY-45

H2-D1
type: EnsemblDatabaseReference

Ppp1r1b DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 2.28572930905241E-7
refers to: 1451331_at
refers to: Ppp1r1b
t statistic: -9.60036415897511

1442810_x_at
type: EFO_0005072
part of: A-AFFY-45

1417954_at
type: EFO_0005072
part of: A-AFFY-45

Plcb1
type: EnsemblDatabaseReference

Ptgs2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.15409203109511E-6
refers to: Ptgs2
refers to: 1417263_at
t statistic: -8.13279423970488

Capn10 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.27545508614323E-11
refers to: Capn10
refers to: 1452959_a_at
t statistic: 19.7447181833748

1416287_at
type: EFO_0005072
part of: A-AFFY-45

Oasl2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 1.88653835728911E-5
refers to: Oasl2
refers to: 1453196_a_at
t statistic: 6.95137386167044

Ifi27l2a
type: EnsemblDatabaseReference

Ier5l DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 7.48300479550949E-9
refers to: Ier5l
refers to: 1419066_at
t statistic: -13.1789932371618

Myh7 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.8
p value: 1.97124907246732E-8
refers to: 1448553_at
refers to: Myh7
t statistic: -12.2292592330959

Rasl10a DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 2.3583733960652E-10
refers to: Rasl10a
refers to: 1427975_at
t statistic: -17.0812393331171

Nos1ap DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 4.79816907890685E-7
refers to: Nos1ap
refers to: 1430442_at
t statistic: -9.07666934893638

Gfra2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.88074356498816E-8
refers to: Gfra2
refers to: 1433716_x_at
t statistic: -11.0258713367868

Abi3bp UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.00272383943124663
refers to: Abi3bp
refers to: 1427053_at
t statistic: 6.00717035498702

1459372_at
type: EFO_0005072
part of: A-AFFY-45

1434375_at
type: EFO_0005072
part of: A-AFFY-45

Enkur
type: EnsemblDatabaseReference

Pbx3
type: EnsemblDatabaseReference

1427683_at
type: EFO_0005072
part of: A-AFFY-45

Sfmbt2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 9.68838192529938E-12
refers to: Sfmbt2
refers to: 1434353_at
t statistic: 20.1179308227802

Arc
type: EnsemblDatabaseReference

AFFX-18SRNAMur/X00686_5_at
type: EFO_0005072
part of: A-AFFY-45

Lamp5 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.61374569541081E-9
refers to: Lamp5
refers to: 1423853_at
t statistic: -14.8002557682746

BC030499 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 9.8195834737018E-7
refers to: 1444656_at
refers to: BC030499
t statistic: -8.5700842142191

1440557_at
type: EFO_0005072
part of: A-AFFY-45

(Sample) genotype/R6/2::HDAC4het
type: EFO_0000001
property type: genotype
property value: R6/2::HDAC4het

Pou4f1
type: EnsemblDatabaseReference

Dmrt2
type: EnsemblDatabaseReference

1428105_at
type: EFO_0005072
part of: A-AFFY-45

Camk2n1
type: EnsemblDatabaseReference

Fzd3 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.90097328432389E-5
refers to: Fzd3
refers to: 1438101_at
t statistic: -6.69737878629426

Zfp800 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 2.2229093782906E-6
refers to: 1437581_at
refers to: Zfp800
t statistic: -8.00933259890922

Homer1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7
p value: 2.21896541804171E-6
refers to: Homer1
refers to: 1436387_at
t statistic: -8.01284728309088

1456685_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936845
type: Assay
has participant: A-AFFY-45

Palm2
type: EnsemblDatabaseReference

Ptgs2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.64794582955539E-6
refers to: Ptgs2
refers to: 1417262_at
t statistic: -8.21760955788165

1438732_at
type: EFO_0005072
part of: A-AFFY-45

Sp8
type: EnsemblDatabaseReference

Tnnc1
type: EnsemblDatabaseReference

Shisa3
type: EnsemblDatabaseReference

Wisp1
type: EnsemblDatabaseReference

H2-D1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.0284907260987747
refers to: H2-D1
refers to: 1451931_x_at
t statistic: 2.85264944779028

Myl4
type: EnsemblDatabaseReference

Nktr DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.71888957702096E-6
refers to: Nktr
refers to: 1440804_at
t statistic: -8.18626883803663

Camkk2
type: EnsemblDatabaseReference

1434984_at
type: EFO_0005072
part of: A-AFFY-45

S100a5
type: EnsemblDatabaseReference

Nmb
type: EnsemblDatabaseReference

Kcnj9
type: EnsemblDatabaseReference

1439767_at
type: EFO_0005072
part of: A-AFFY-45

Abi3bp DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 8.68732179294745E-6
refers to: Abi3bp
refers to: 1427053_at
t statistic: -7.16480803982361

Oasl2
type: EnsemblDatabaseReference

Arc DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.0140940663629337
refers to: 1418687_at
refers to: Arc
t statistic: -3.28843377213783

Gm12300 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.58990560783893E-6
refers to: 1427867_at
refers to: Gm12300
t statistic: -8.6166176827383

Arpp21 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.59743189107755E-8
refers to: Arpp21
refers to: 1451280_at
t statistic: -11.1495919342566

Phka2
type: EnsemblDatabaseReference

(Assay) GSM936871
type: Assay
has participant: A-AFFY-45

Ptgs2
type: EnsemblDatabaseReference

Arpp19 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.4573143816943E-11
refers to: Arpp19
refers to: 1422609_at
t statistic: -18.9737981761912

Ano3 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.59226728592154E-4
refers to: 1443612_at
refers to: Ano3
t statistic: -5.52124133265463

R3hdm1 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.93213408939117E-6
refers to: 1457336_at
refers to: R3hdm1
t statistic: -7.21955475968701

(Assay) GSM936841
type: Assay
has participant: A-AFFY-45

1440005_at
type: EFO_0005072
part of: A-AFFY-45

Scn9a UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 4.25636837309179E-5
refers to: Scn9a
refers to: 1442810_x_at
t statistic: 6.45464560158217

Fzd3
type: EnsemblDatabaseReference

Brca1
type: EnsemblDatabaseReference

Egr2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.1
p value: 4.8286946970277E-4
refers to: 1427683_at
refers to: Egr2
t statistic: -5.08215964999466

Fst
type: EnsemblDatabaseReference

Camk2n1 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.9
p value: 0.0033131438692007
refers to: Camk2n1
refers to: 1440455_at
t statistic: -4.05732304488632

Tpx2
type: EnsemblDatabaseReference

1457092_at
type: EFO_0005072
part of: A-AFFY-45

1452378_at
type: EFO_0005072
part of: A-AFFY-45

Ddit4l DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7
p value: 2.86882057431779E-12
refers to: 1444139_at
refers to: Ddit4l
t statistic: -22.0418896495564

1448285_at
type: EFO_0005072
part of: A-AFFY-45

1424474_a_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936864
type: Assay
has participant: A-AFFY-45

1457557_at
type: EFO_0005072
part of: A-AFFY-45

Nhsl2
type: EnsemblDatabaseReference

RP24-439I22.1
type: EnsemblDatabaseReference

Ptgs2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.56066768000884E-7
refers to: 1417262_at
refers to: Ptgs2
t statistic: -9.27639372515494

Arc DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 0.00441420919961665
refers to: 1418687_at
refers to: Arc
t statistic: -3.81613888755989

Sp8 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8
p value: 0.0267486316210759
refers to: 1440519_at
refers to: Sp8
t statistic: 4.28778177474707

Ryr1
type: EnsemblDatabaseReference

Cnksr2
type: EnsemblDatabaseReference

Nfya UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.6401923418667E-12
refers to: Nfya
refers to: 1452560_a_at
t statistic: 23.5784512283784

Onecut2 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 8.62526775320014E-10
refers to: Onecut2
refers to: 1440005_at
t statistic: 14.5932443532297

1427054_s_at
type: EFO_0005072
part of: A-AFFY-45

Gabrd DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.3583733960652E-10
refers to: 1449980_a_at
refers to: Gabrd
t statistic: -17.0948613803392

1424606_at
type: EFO_0005072
part of: A-AFFY-45

1452560_a_at
type: EFO_0005072
part of: A-AFFY-45

Cdhr1 UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 0.042102054305895
refers to: 1418304_at
refers to: Cdhr1
t statistic: 3.70436628754194

Mid1
type: EnsemblDatabaseReference

1428664_at
type: EFO_0005072
part of: A-AFFY-45

1440519_at
type: EFO_0005072
part of: A-AFFY-45

Prps1l3
type: EnsemblDatabaseReference

Ighm DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 8.46098848926612E-4
refers to: Ighm
refers to: 1427351_s_at
t statistic: -4.65229548156037

Fst DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.09076188734166E-9
refers to: Fst
refers to: 1421365_at
t statistic: -14.303591263334

Ighm
type: EnsemblDatabaseReference

Otof DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 2.19048075014285E-8
refers to: Otof
refers to: 1420419_a_at
t statistic: -12.1381596226247

Vip
type: EnsemblDatabaseReference

1420546_at
type: EFO_0005072
part of: A-AFFY-45

Rph3a
type: EnsemblDatabaseReference

Ano3
type: EnsemblDatabaseReference

Cplx3
type: EnsemblDatabaseReference

1422825_at
type: EFO_0005072
part of: A-AFFY-45

BC030499
type: EnsemblDatabaseReference

Rspo1
type: EnsemblDatabaseReference

(Assay) GSM936875
type: Assay
has participant: A-AFFY-45

9230110C19Rik
type: EnsemblDatabaseReference

Vps37a
type: EnsemblDatabaseReference

1449340_at
type: EFO_0005072
part of: A-AFFY-45

Pdyn
type: EnsemblDatabaseReference

(Assay) GSM936853
type: Assay
has participant: A-AFFY-45

Nhsl2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 8.00332556282388E-5
refers to: Nhsl2
refers to: 1438732_at
t statistic: -5.89084040191667

1438403_s_at
type: EFO_0005072
part of: A-AFFY-45

Gfra2
type: EnsemblDatabaseReference

Arhgap32 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.00507699093981E-7
refers to: Arhgap32
refers to: 1438451_at
t statistic: -10.2604897700135

1417262_at
type: EFO_0005072
part of: A-AFFY-45

Nfya
type: EnsemblDatabaseReference

1810022K09Rik UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 1.17056204173026E-7
refers to: 1810022K09Rik
refers to: 1434493_at
t statistic: 10.6503079106654

(Assay) GSM936867
type: Assay
has participant: A-AFFY-45

Plk5 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 2.4840529094536E-10
refers to: Plk5
refers to: 1434984_at
t statistic: -15.9601135614134

1421385_a_at
type: EFO_0005072
part of: A-AFFY-45

Rasl10a
type: EnsemblDatabaseReference

Slc1a2
type: EnsemblDatabaseReference

Lamp5
type: EnsemblDatabaseReference

Crhbp DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 3.58485118860247E-9
refers to: Crhbp
refers to: 1436127_at
t statistic: -13.1997492037762

Penk DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 8.34149126696422E-8
refers to: Penk
refers to: 1427038_at
t statistic: -10.4165454116847

Prps1l3 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 7.95442775764532E-11
refers to: 1454814_s_at
refers to: Prps1l3
t statistic: 18.7993389591076

A330076H08Rik DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 0.00318362060146883
refers to: A330076H08Rik
refers to: 1457557_at
t statistic: -4.07826633120845

Tbx21
type: EnsemblDatabaseReference

Fam19a1
type: EnsemblDatabaseReference

Arpp19
type: EnsemblDatabaseReference

1448594_at
type: EFO_0005072
part of: A-AFFY-45

1455087_at
type: EFO_0005072
part of: A-AFFY-45

1449319_at
type: EFO_0005072
part of: A-AFFY-45

Pttg1
type: EnsemblDatabaseReference

Tnfrsf25
type: EnsemblDatabaseReference

1434493_at
type: EFO_0005072
part of: A-AFFY-45

Gm10010 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.38404442394022E-6
refers to: Gm10010
refers to: 1440290_at
t statistic: -7.74603702554836

Slc1a2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 3.04517180593282E-4
refers to: Slc1a2
refers to: 1439940_at
t statistic: -5.1778905184262

(Sample) clinical information/Huntington's disease mouse model
type: EFO_0000001
property type: clinical information
property value: Huntington's disease mouse model

Ddit4l DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 3.29879647423438E-10
refers to: Ddit4l
refers to: 1451751_at
t statistic: -16.6983857730225

(Assay) GSM936869
type: Assay
has participant: A-AFFY-45

Rgs4 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.56874992840493E-9
refers to: Rgs4
refers to: 1416287_at
t statistic: -13.9687274212806

Pou4f1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.9
p value: 3.08922033502512E-9
refers to: Pou4f1
refers to: 1429668_at
t statistic: 13.3374417944175

Otof
type: EnsemblDatabaseReference

Oasl2
type: EnsemblDatabaseReference

Stard8
type: EnsemblDatabaseReference

1418733_at
type: EFO_0005072
part of: A-AFFY-45

Ankrd63
type: EnsemblDatabaseReference

Plk5
type: EnsemblDatabaseReference

Pou4f1 UP in 'R6/2::HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 7.88581742404337E-9
refers to: Pou4f1
refers to: 1429667_at
t statistic: 12.4308317004481

1427306_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936846
type: Assay
has participant: A-AFFY-45

Cks1b UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 5.73695072300509E-10
refers to: Cks1b
refers to: 1416698_a_at
t statistic: 15.999846731834

1419405_at
type: EFO_0005072
part of: A-AFFY-45

1421365_at
type: EFO_0005072
part of: A-AFFY-45

Rgs4
type: EnsemblDatabaseReference

1417489_at
type: EFO_0005072
part of: A-AFFY-45

Abi3bp DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 4.9609653244789E-7
refers to: Abi3bp
refers to: 1427053_at
t statistic: -9.47332555415631

1438565_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936857
type: Assay
has participant: A-AFFY-45

Arpp21
type: EnsemblDatabaseReference

(Sample) genotype/wild type genotype
type: EFO_0000001
property type: genotype
property value: wild type genotype

Lamp5 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.97707373713116E-11
refers to: 1423853_at
refers to: Lamp5
t statistic: -19.1001779454025

(Assay) GSM936842
type: Assay
has participant: A-AFFY-45

Kctd14
type: EnsemblDatabaseReference

Prss22
type: EnsemblDatabaseReference

Scn4b
type: EnsemblDatabaseReference

1449961_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936863
type: Assay
has participant: A-AFFY-45

Crhbp
type: EnsemblDatabaseReference

Crhbp DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 1.83812705438651E-8
refers to: Crhbp
refers to: 1436127_at
t statistic: -12.2893349836117

(Sample) organism part/brain cortex
type: EFO_0000001
property type: organism part
property value: brain cortex

Twist1 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 3.03953296109561E-5
refers to: Twist1
refers to: 1418733_at
t statistic: 6.65755981187594

1420957_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936851
type: Assay
has participant: A-AFFY-45

Npas4
type: EnsemblDatabaseReference

Onecut2 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8
p value: 1.63644029107066E-11
refers to: Onecut2
refers to: 1460044_at
t statistic: 22.4782443270099

Ankrd63 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 9.96844959829006E-6
refers to: Ankrd63
refers to: 1443287_at
t statistic: -7.35347100134689

Ier5l
type: EnsemblDatabaseReference

(Sample) genotype/R6/2
type: EFO_0000001
property type: genotype
property value: R6/2

Itpka
type: EnsemblDatabaseReference

Analysis of 'R6/2::HDAC4het' vs 'wild type genotype'
type: MicroarrayDifferentialExpressionAnalysis

Ier5l DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 9.8188844127186E-10
refers to: Ier5l
refers to: 1419066_at
t statistic: -14.4666117220469

Ovgp1
type: EnsemblDatabaseReference

1425573_a_at
type: EFO_0005072
part of: A-AFFY-45

Pbx3
type: EnsemblDatabaseReference

Pde10a
type: EnsemblDatabaseReference

Tulp4 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 3.99640456391425E-5
refers to: 1440282_at
refers to: Tulp4
t statistic: -6.27421407247525

Dmrt2
type: EnsemblDatabaseReference

(Assay) GSM936844
type: Assay
has participant: A-AFFY-45

(Assay) GSM936868
type: Assay
has participant: A-AFFY-45

1438101_at
type: EFO_0005072
part of: A-AFFY-45

1426526_s_at
type: EFO_0005072
part of: A-AFFY-45

Npy2r DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 2.64576423147188E-5
refers to: Npy2r
refers to: 1417489_at
t statistic: -6.74126894637893

Camk2n1
type: EnsemblDatabaseReference

Cartpt
type: EnsemblDatabaseReference

Cartpt DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.01804545917927E-6
refers to: Cartpt
refers to: 1422825_at
t statistic: -7.3889017346414

Asap1
type: EnsemblDatabaseReference

Rgs13 UP in 'R6/2' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.2
p value: 1.24871608367018E-12
refers to: Rgs13
refers to: 1442263_at
t statistic: 27.1527319975669

1434008_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM936840
type: Assay
has participant: A-AFFY-45

Nmb UP in 'HDAC4het' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0184391923420322
refers to: 1419405_at
refers to: Nmb
t statistic: 4.55603808700605

Rspo1
type: EnsemblDatabaseReference

1434353_at
type: EFO_0005072
part of: A-AFFY-45

Sp8
type: EnsemblDatabaseReference

Twist1
type: EnsemblDatabaseReference

1423853_at
type: EFO_0005072
part of: A-AFFY-45

Shisa3
type: EnsemblDatabaseReference

Wisp1
type: EnsemblDatabaseReference

1418759_at
type: EFO_0005072
part of: A-AFFY-45

Rph3a DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 5.82514750371995E-7
refers to: Rph3a
refers to: 1449961_at
t statistic: -8.93183073743483

Myl4
type: EnsemblDatabaseReference

Nptx2 DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.896641558278E-8
refers to: 1420720_at
refers to: Nptx2
t statistic: -10.4719688242804

Scn4b DOWN in 'R6/2::HDAC4het' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6
p value: 1.30294265899539E-8
refers to: Scn4b
refers to: 1434008_at
t statistic: -11.9406967016053

Myo7a
type: EnsemblDatabaseReference

Egr2
type: EnsemblDatabaseReference

1454137_s_at
type: EFO_0005072
part of: A-AFFY-45

1424629_at
type: EFO_0005072
part of: A-AFFY-45

S100a5
type: EnsemblDatabaseReference

Kcnj9
type: EnsemblDatabaseReference

Camkk2 DOWN in 'R6/2' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 1.81973550392691E-11
refers to: Camkk2
refers to: 1424474_a_at
t statistic: -21.5656380192993

1449927_at
type: EFO_0005072
part of: A-AFFY-45