AT4G27280 UP in 'frb1 mutant' vs 'wild type'
AT2G33850 DOWN in 'frb1 mutant' vs 'wild type'
AtCYS2 UP in 'frb1 mutant' vs 'wild type'
AT3G46600 UP in 'frb1 mutant' vs 'wild type'
AT1G47980 UP in 'frb1 mutant' vs 'wild type'
AT5G01030 DOWN in 'frb1 mutant' vs 'wild type'
LEA18 UP in 'frb1 mutant' vs 'wild type'
AT3G05260 UP in 'frb1 mutant' vs 'wild type'
AR781 UP in 'frb1 mutant' vs 'wild type'
AT2G20870 DOWN in 'frb1 mutant' vs 'wild type'
CRK30 DOWN in 'frb1 mutant' vs 'wild type'
AT1G32560 UP in 'frb1 mutant' vs 'wild type'
AT5G01075 DOWN in 'frb1 mutant' vs 'wild type'
BETA-VPE UP in 'frb1 mutant' vs 'wild type'
ATPER1 UP in 'frb1 mutant' vs 'wild type'
AT1G75900 UP in 'frb1 mutant' vs 'wild type'
AT1G29090 UP in 'frb1 mutant' vs 'wild type'
AT3G04210 DOWN in 'frb1 mutant' vs 'wild type'
BGLU10 UP in 'frb1 mutant' vs 'wild type'
ATNAS2 DOWN in 'frb1 mutant' vs 'wild type'
CYP81D1 UP in 'frb1 mutant' vs 'wild type'
AT1G80130 UP in 'frb1 mutant' vs 'wild type'
AT2G28490 UP in 'frb1 mutant' vs 'wild type'
AT3G16530 DOWN in 'frb1 mutant' vs 'wild type'
ATTI1 UP in 'frb1 mutant' vs 'wild type'
AT4G28040 UP in 'frb1 mutant' vs 'wild type'
BGLU11 UP in 'frb1 mutant' vs 'wild type'
AT2G47780 UP in 'frb1 mutant' vs 'wild type'
ATBCB UP in 'frb1 mutant' vs 'wild type'
AT3G15720 UP in 'frb1 mutant' vs 'wild type'
AT5G01015 DOWN in 'frb1 mutant' vs 'wild type'
AT1G32920 UP in 'frb1 mutant' vs 'wild type'
AT3G17520 UP in 'frb1 mutant' vs 'wild type'
AT2G43620 UP in 'frb1 mutant' vs 'wild type'
GRXC13 DOWN in 'frb1 mutant' vs 'wild type'
GRP3S UP in 'frb1 mutant' vs 'wild type'
WRKY33 UP in 'frb1 mutant' vs 'wild type'
ATOCT3 DOWN in 'frb1 mutant' vs 'wild type'
AT1G73480 UP in 'frb1 mutant' vs 'wild type'
CYP72A8 UP in 'frb1 mutant' vs 'wild type'
ATPMEPCRB UP in 'frb1 mutant' vs 'wild type'
OLEO1 UP in 'frb1 mutant' vs 'wild type'
LCR78 UP in 'frb1 mutant' vs 'wild type'
ATBCAT-2 UP in 'frb1 mutant' vs 'wild type'
BGLU44 UP in 'frb1 mutant' vs 'wild type'
Cell adhesion in plants is mediated predominantly by pectins, a group of complex cell wall associated polysaccharides. An Arabidopsis mutant, friable1 (frb1), was identified through a screen of T-DNA insertion lines that exhibited defective cell adhesion. Interestingly, the frb1 plants displayed both cell and organ dissociations and also ectopic organ fusions. The FRB1 gene encodes a Golgi-localized, plant specific protein with only weak sequence similarities to known proteins (DUF246). Unlike other cell adhesion deficient mutants, frb1 mutants do not have reduced levels of adhesion related cell wall polymers, such as pectins. Instead, FRB1 affects the abundance of galactose- and arabinose-containing oligosaccharides in the Golgi. Furthermore, frb1 mutants displayed alteration in pectin methylesterification, cell wall associated extensins and xyloglucan microstructure. We propose that abnormal FRB1 action has pleiotropic consequences on wall architecture, affecting both the extensin and pectin matrices, with consequent changes to the biomechanical properties of the wall and middle lamella, thereby influencing cell-cell adhesion. Microarrays were used to determine the differences in global expression of friable1 mutant plants, which have cell adhesion defects, and compared these to wild-type plants. RNA was extracted from seedlings grown on 0.5X MS for 10 days under constant illumination.
AT4G01390 DOWN in 'frb1 mutant' vs 'wild type'
DREB26 UP in 'frb1 mutant' vs 'wild type'
LBD41 DOWN in 'frb1 mutant' vs 'wild type'
(Factor value) GENOTYPE/wild type genotype
AT1G52000 UP in 'frb1 mutant' vs 'wild type'
AT2G37870 UP in 'frb1 mutant' vs 'wild type'
ALPHA-TIP UP in 'frb1 mutant' vs 'wild type'
AT1G66100 DOWN in 'frb1 mutant' vs 'wild type'
WRKY70 UP in 'frb1 mutant' vs 'wild type'
AT3G12900 DOWN in 'frb1 mutant' vs 'wild type'
WRKY40 UP in 'frb1 mutant' vs 'wild type'
ATMGL UP in 'frb1 mutant' vs 'wild type'
PAP85 UP in 'frb1 mutant' vs 'wild type'
ATXTH19 UP in 'frb1 mutant' vs 'wild type'
PGL5 DOWN in 'frb1 mutant' vs 'wild type'
Analysis of 'frb1 mutant' vs 'wild type'
AT2G21820 UP in 'frb1 mutant' vs 'wild type'
AT1G56300 UP in 'frb1 mutant' vs 'wild type'
HSPRO2 UP in 'frb1 mutant' vs 'wild type'
AT3G01570 UP in 'frb1 mutant' vs 'wild type'
AT3G27520 UP in 'frb1 mutant' vs 'wild type'
BGLU19 UP in 'frb1 mutant' vs 'wild type'
AT4G10270 DOWN in 'frb1 mutant' vs 'wild type'
DELTA-VPE UP in 'frb1 mutant' vs 'wild type'
AT1G66940 DOWN in 'frb1 mutant' vs 'wild type'
AKR4C8 UP in 'frb1 mutant' vs 'wild type'
GASA3 UP in 'frb1 mutant' vs 'wild type'