TUBB2A UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.42585743702143
p value: 0.0326801960832622
refers to: TUBB2A
refers to: 204141_at
t statistic: 4.88555309569816

SMOC2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.12985753930774
p value: 0.0380175467162179
refers to: SMOC2
refers to: 223235_s_at
t statistic: 4.65011347731531

NNMT
type: EnsemblDatabaseReference

202499_s_at
type: EFO_0005072
part of: A-AFFY-44

218935_at
type: EFO_0005072
part of: A-AFFY-44

SERINC5
type: EnsemblDatabaseReference

212977_at
type: EFO_0005072
part of: A-AFFY-44

TSPAN11 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.46204709593202
p value: 0.0326801960832622
refers to: TSPAN11
refers to: 227610_at
t statistic: 4.91550204815718

PDE4D
type: EnsemblDatabaseReference

FAT4 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.29247273505474
p value: 0.0488828081445063
refers to: FAT4
refers to: 219427_at
t statistic: 4.01156404677137

ERRFI1
type: EnsemblDatabaseReference

RIN2
type: EnsemblDatabaseReference

CXCL14
type: EnsemblDatabaseReference

EHD3
type: EnsemblDatabaseReference

WNT5A UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.53537355140184
p value: 0.0380175467162179
refers to: WNT5A
refers to: 205990_s_at
t statistic: 4.6439952246245

COL8A2
type: EnsemblDatabaseReference

CXCL14 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.01471811709513
p value: 0.0102431027621567
refers to: 218002_s_at
refers to: CXCL14
t statistic: 7.92845113662336

204491_at
type: EFO_0005072
part of: A-AFFY-44

CRISPLD2
type: EnsemblDatabaseReference

NNMT UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.87379908358097
p value: 0.0408864090987054
refers to: 202237_at
refers to: NNMT
t statistic: 4.44482578849622

(Assay) GSM592231
type: Assay
has participant: A-AFFY-44

NR4A2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 3.20253089841196
p value: 0.0408864090987054
refers to: NR4A2
refers to: 204622_x_at
t statistic: 4.42425240309477

ERRFI1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8597123970571
p value: 0.0452336418776694
refers to: ERRFI1
refers to: 224657_at
t statistic: 4.22928453073995

SNAI2
type: EnsemblDatabaseReference

(Sample) organism part/bone
type: EFO_0000298
property type: organism part
property value: bone

SLC30A1
type: EnsemblDatabaseReference

MATN2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.17167275614701
p value: 0.0452336418776694
refers to: MATN2
refers to: 202350_s_at
t statistic: 4.20912463983125

ACKR3
type: EnsemblDatabaseReference

DIRAS3
type: EnsemblDatabaseReference

TUBB2A
type: EnsemblDatabaseReference

LAPTM5
type: EnsemblDatabaseReference

GAS1
type: EnsemblDatabaseReference

ENPP2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.66315740978207
p value: 0.0452336418776694
refers to: 209392_at
refers to: ENPP2
t statistic: 4.26088168765169

MSX1
type: EnsemblDatabaseReference

CDC42EP5
type: EnsemblDatabaseReference

FAT4
type: EnsemblDatabaseReference

213001_at
type: EFO_0005072
part of: A-AFFY-44

RGS2
type: EnsemblDatabaseReference

SPON1
type: EnsemblDatabaseReference

MATN2
type: EnsemblDatabaseReference

SNAI2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.54242771709011
p value: 0.0479903358867681
refers to: SNAI2
refers to: 213139_at
t statistic: 4.08267829179149

MSX1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.93629067620681
p value: 0.036322345673279
refers to: MSX1
refers to: 205932_s_at
t statistic: 4.73234925456088

(Assay) GSM592232
type: Assay
has participant: A-AFFY-44

215506_s_at
type: EFO_0005072
part of: A-AFFY-44

226677_at
type: EFO_0005072
part of: A-AFFY-44

227481_at
type: EFO_0005072
part of: A-AFFY-44

INHBA
type: EnsemblDatabaseReference

RIN2
type: EnsemblDatabaseReference

TNFSF11 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.50357021605053
p value: 0.0322747455939071
refers to: TNFSF11
refers to: 210643_at
t statistic: 5.20327410776968

PDE7B
type: EnsemblDatabaseReference

MAFF
type: EnsemblDatabaseReference

CXCL14
type: EnsemblDatabaseReference

ACKR3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.41150702142748
p value: 0.0452336418776694
refers to: 212977_at
refers to: ACKR3
t statistic: 4.30481534506659

230109_at
type: EFO_0005072
part of: A-AFFY-44

212812_at
type: EFO_0005072
part of: A-AFFY-44

ENPP2
type: EnsemblDatabaseReference

INHBA UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.0088048376935
p value: 0.0452336418776694
refers to: INHBA
refers to: 227140_at
t statistic: 4.21839512120825

209465_x_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM592236
type: Assay
has participant: A-AFFY-44

CRISPLD2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.01426685233969
p value: 0.0234522911600559
refers to: 221541_at
refers to: CRISPLD2
t statistic: 5.85124420489427

ZNF521
type: EnsemblDatabaseReference

SNAI2
type: EnsemblDatabaseReference

SLC2A3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.81017564739378
p value: 0.0234522911600559
refers to: SLC2A3
refers to: 202499_s_at
t statistic: 5.58569137444669

COL14A1
type: EnsemblDatabaseReference

ACKR3
type: EnsemblDatabaseReference

CD83 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.45437116859693
p value: 0.0322747455939071
refers to: CD83
refers to: 204440_at
t statistic: 5.11942926958822

212865_s_at
type: EFO_0005072
part of: A-AFFY-44

202949_s_at
type: EFO_0005072
part of: A-AFFY-44

MAFF UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.83644452450762
p value: 0.0234522911600559
refers to: MAFF
refers to: 36711_at
t statistic: 5.62046808751862

(Sample) xenograft/human bone implanted in SCID mice then engrafted with the myeloma cell line, Hg
type: EFO_0000001
property type: xenograft
property value: human bone implanted in SCID mice then engrafted with the myeloma cell line, Hg

(Assay) GSM592239
type: Assay
has participant: A-AFFY-44

(Factor value) COMPOUND/saline
type: EFO_0002677
property type: COMPOUND
property value: saline

CDC42EP5 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.58207610006193
p value: 0.0479903358867681
refers to: CDC42EP5
refers to: 227850_x_at
t statistic: 4.06398594593858

A-AFFY-44
type: EFO_0000269

FAT4
type: EnsemblDatabaseReference

221900_at
type: EFO_0005072
part of: A-AFFY-44

SLC2A3
type: EnsemblDatabaseReference

CEBPD UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.37794576231767
p value: 0.036322345673279
refers to: 203973_s_at
refers to: CEBPD
t statistic: 4.73541506929473

RGS2
type: EnsemblDatabaseReference

MGST1
type: EnsemblDatabaseReference

SPON1
type: EnsemblDatabaseReference

(Factor value) COMPOUND/parathyroid hormone 80
type: EFO_0000001
property type: COMPOUND
property value: parathyroid hormone 80

209392_at
type: EFO_0005072
part of: A-AFFY-44

36711_at
type: EFO_0005072
part of: A-AFFY-44

228181_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM592235
type: Assay
has participant: A-AFFY-44

TNFSF11
type: EnsemblDatabaseReference

222484_s_at
type: EFO_0005072
part of: A-AFFY-44

202388_at
type: EFO_0005072
part of: A-AFFY-44

224657_at
type: EFO_0005072
part of: A-AFFY-44

TUBB2A
type: EnsemblDatabaseReference

DIRAS3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.95056080364779
p value: 0.0114198530375262
refers to: DIRAS3
refers to: 215506_s_at
t statistic: 7.25396406606473

Homo sapiens
type: OBI_0100026

PDE7B
type: EnsemblDatabaseReference

MAFF
type: EnsemblDatabaseReference

CD83
type: EnsemblDatabaseReference

NR4A3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.59756502648896
p value: 0.0232995634337596
refers to: NR4A3
refers to: 209959_at
t statistic: 6.16772101537752

202237_at
type: EFO_0005072
part of: A-AFFY-44

MSX1
type: EnsemblDatabaseReference

FHL2
type: EnsemblDatabaseReference

CDC42EP5
type: EnsemblDatabaseReference

MGST1 DOWN in 'parathyroid hormone' vs 'saline'
type: DecreasedDifferentialExpressionRatio
fold change: -1.29817172251991
p value: 0.0479903358867681
refers to: 1565162_s_at
refers to: MGST1
t statistic: -4.0447405140819

SMOC2
type: EnsemblDatabaseReference

Analysis of 'parathyroid hormone' vs 'saline'
type: MicroarrayDifferentialExpressionAnalysis

ZNF521
type: EnsemblDatabaseReference

1565162_s_at
type: EFO_0005072
part of: A-AFFY-44

CH25H UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.01736295531124
p value: 0.0452336418776694
refers to: 206932_at
refers to: CH25H
t statistic: 4.31846842486921

NR4A3
type: EnsemblDatabaseReference

ZNF521 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.83772761258043
p value: 0.0476391428309858
refers to: ZNF521
refers to: 226677_at
t statistic: 4.16211546780641

COL14A1
type: EnsemblDatabaseReference

ANGPTL2
type: EnsemblDatabaseReference

209684_at
type: EFO_0005072
part of: A-AFFY-44

WNT5A
type: EnsemblDatabaseReference

LAPTM5 DOWN in 'parathyroid hormone' vs 'saline'
type: DecreasedDifferentialExpressionRatio
fold change: -1.34963155723941
p value: 0.0326801960832622
refers to: LAPTM5
refers to: 201721_s_at
t statistic: -4.86449931352579

PTN
type: EnsemblDatabaseReference

CH25H
type: EnsemblDatabaseReference

NR4A2
type: EnsemblDatabaseReference

223235_s_at
type: EFO_0005072
part of: A-AFFY-44

204440_at
type: EFO_0005072
part of: A-AFFY-44

MGST1
type: EnsemblDatabaseReference

FHL2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.77980449359599
p value: 0.0322747455939071
refers to: 202949_s_at
refers to: FHL2
t statistic: 5.07196679616485

NR4A2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 3.14153347221522
p value: 0.0408864090987054
refers to: 216248_s_at
refers to: NR4A2
t statistic: 4.44494089613467

205990_s_at
type: EFO_0005072
part of: A-AFFY-44

NNMT
type: EnsemblDatabaseReference

SERINC5
type: EnsemblDatabaseReference

204621_s_at
type: EFO_0005072
part of: A-AFFY-44

PDE7B UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.11915616161207
p value: 0.0479903358867681
refers to: 230109_at
refers to: PDE7B
t statistic: 4.03940984492396

216248_s_at
type: EFO_0005072
part of: A-AFFY-44

TSPAN11
type: EnsemblDatabaseReference

METRNL
type: EnsemblDatabaseReference

221541_at
type: EFO_0005072
part of: A-AFFY-44

CD83
type: EnsemblDatabaseReference

227850_x_at
type: EFO_0005072
part of: A-AFFY-44

202350_s_at
type: EFO_0005072
part of: A-AFFY-44

(Sample) disease/myeloma
type: EFO_0001378
property type: disease
property value: myeloma

FHL2
type: EnsemblDatabaseReference

204141_at
type: EFO_0005072
part of: A-AFFY-44

SLC2A3
type: EnsemblDatabaseReference

(Assay) GSM592238
type: Assay
has participant: A-AFFY-44

SMOC2
type: EnsemblDatabaseReference

EHD3
type: EnsemblDatabaseReference

CNKSR3
type: EnsemblDatabaseReference

205932_s_at
type: EFO_0005072
part of: A-AFFY-44

ANGPTL2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.43878512995931
p value: 0.0408864090987054
refers to: ANGPTL2
refers to: 213001_at
t statistic: 4.43873721341064

NR4A3
type: EnsemblDatabaseReference

213994_s_at
type: EFO_0005072
part of: A-AFFY-44

206932_at
type: EFO_0005072
part of: A-AFFY-44

FRMD6
type: EnsemblDatabaseReference

CEBPD
type: EnsemblDatabaseReference

SERINC5 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.60737838543431
p value: 0.0380175467162179
refers to: SERINC5
refers to: 212812_at
t statistic: 4.61855249972577

201721_s_at
type: EFO_0005072
part of: A-AFFY-44

WNT5A
type: EnsemblDatabaseReference

TNFSF11
type: EnsemblDatabaseReference

PTN
type: EnsemblDatabaseReference

E-GEOD-24068
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: The data present global gene expression profile of whole human bones, implanted in SCID mice (SCID-hu model), then engrafted with the myeloma cell line, Hg, and treated with saline or PTH for 4 weeks. SCID-hu mice were prepared by subcutaneous implantation of human bone in SCID mice. The human myeloma cell line, Hg was injected directly into the implanted bone in SCID-hum mice. Upon establishment of myeloma growth as determined by measurement of circulating human immunoglobulins in SCID-hu mice sera, the mice were treated with saline or intermittent PTH (parathyroid hormone, 80 ug/kg/day) for 4 weeks. At the end of the experiment, the human bones from SCID-hu mice were snap frozen in liquid nitrogen. RNA extracted from these bones was subjected to global gene expression profile using Affymetrix U133-Plus microarray.

NR4A2
type: EnsemblDatabaseReference

COL14A1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.44627325638004
p value: 0.0452336418776694
refers to: 212865_s_at
refers to: COL14A1
t statistic: 4.21498430252217

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

NR4A2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.57709893547832
p value: 0.0479903358867681
refers to: NR4A2
refers to: 204621_s_at
t statistic: 4.03481600550229

COL8A2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.46785857723084
p value: 0.0479903358867681
refers to: 221900_at
refers to: COL8A2
t statistic: 4.13340733460359

PDE4D
type: EnsemblDatabaseReference

GAS1
type: EnsemblDatabaseReference

204457_s_at
type: EFO_0005072
part of: A-AFFY-44

ERRFI1
type: EnsemblDatabaseReference

PTN UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.90864781172391
p value: 0.0479903358867681
refers to: PTN
refers to: 209465_x_at
t statistic: 4.07631717461349

SPON1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.96248168706868
p value: 0.0479903358867681
refers to: SPON1
refers to: 213994_s_at
t statistic: 4.09127583782216

209959_at
type: EFO_0005072
part of: A-AFFY-44

219427_at
type: EFO_0005072
part of: A-AFFY-44

218002_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM592233
type: Assay
has participant: A-AFFY-44

213139_at
type: EFO_0005072
part of: A-AFFY-44

COL8A2
type: EnsemblDatabaseReference

225464_at
type: EFO_0005072
part of: A-AFFY-44

CNKSR3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.97957581764034
p value: 0.0479903358867681
refers to: 227481_at
refers to: CNKSR3
t statistic: 4.10876146316444

CRISPLD2
type: EnsemblDatabaseReference

225955_at
type: EFO_0005072
part of: A-AFFY-44

203973_s_at
type: EFO_0005072
part of: A-AFFY-44

ANGPTL2
type: EnsemblDatabaseReference

INHBA
type: EnsemblDatabaseReference

(Assay) GSM592237
type: Assay
has participant: A-AFFY-44

GAS1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.57541630229185
p value: 0.0408864090987054
refers to: GAS1
refers to: 204457_s_at
t statistic: 4.41267377546982

227140_at
type: EFO_0005072
part of: A-AFFY-44

SLC30A1
type: EnsemblDatabaseReference

TSPAN11
type: EnsemblDatabaseReference

FRMD6 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.73409916977357
p value: 0.0452336418776694
refers to: 225464_at
refers to: FRMD6
t statistic: 4.24210377392784

DIRAS3
type: EnsemblDatabaseReference

METRNL
type: EnsemblDatabaseReference

CH25H
type: EnsemblDatabaseReference

LAPTM5
type: EnsemblDatabaseReference

210643_at
type: EFO_0005072
part of: A-AFFY-44

SLC30A1 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.42445527440749
p value: 0.0384494900137265
refers to: SLC30A1
refers to: 228181_at
t statistic: 4.58565966652054

CNKSR3
type: EnsemblDatabaseReference

EHD3 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.90035689782014
p value: 0.0234522911600559
refers to: EHD3
refers to: 218935_at
t statistic: 5.88341539143563

ENPP2
type: EnsemblDatabaseReference

PDE4D UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.92099286377291
p value: 0.0326801960832622
refers to: 204491_at
refers to: PDE4D
t statistic: 4.87792328433176

227610_at
type: EFO_0005072
part of: A-AFFY-44

CXCL14 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.48155542078064
p value: 0.0234522911600559
refers to: 222484_s_at
refers to: CXCL14
t statistic: 5.65306760729998

FRMD6
type: EnsemblDatabaseReference

204622_x_at
type: EFO_0005072
part of: A-AFFY-44

MATN2
type: EnsemblDatabaseReference

METRNL UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 1.90031800581051
p value: 0.0326801960832622
refers to: 225955_at
refers to: METRNL
t statistic: 4.8692716605305

RIN2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.63137297240467
p value: 0.0284363473794934
refers to: RIN2
refers to: 209684_at
t statistic: 5.38145061245235

CEBPD
type: EnsemblDatabaseReference

RGS2 UP in 'parathyroid hormone' vs 'saline'
type: IncreasedDifferentialExpressionRatio
fold change: 2.06332282749508
p value: 0.0232995634337596
refers to: RGS2
refers to: 202388_at
t statistic: 6.36293154605799

(Assay) GSM592240
type: Assay
has participant: A-AFFY-44

(Assay) GSM592234
type: Assay
has participant: A-AFFY-44