Lrp8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0112849954939527
refers to: Lrp8

Lactbl1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: Infinity
p value: 3.96733150071139E-41
refers to: Lactbl1

Pycr1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 7.81772803078209E-5
refers to: Pycr1

Kirrel3
type: EnsemblDatabaseReference

Ggact UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 1.70733047847533E-4
refers to: Ggact

(Factor value) CLINICAL_INFORMATION/non-pregnant
type: EFO_0000001
property type: CLINICAL_INFORMATION
property value: non-pregnant

Gas2
type: EnsemblDatabaseReference

Car8
type: EnsemblDatabaseReference

Ern1
type: EnsemblDatabaseReference

Chst11
type: EnsemblDatabaseReference

Socs2
type: EnsemblDatabaseReference

Map6
type: EnsemblDatabaseReference

Reg3b
type: EnsemblDatabaseReference

Rgs2
type: EnsemblDatabaseReference

Hspa1b DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.8
p value: 1.00324994467266E-4
refers to: Hspa1b

Gm16314
type: EnsemblDatabaseReference

(Sample) organism/Mus musculus
type: Mus musculus
property type: organism
property value: Mus musculus

Tmem255a
type: EnsemblDatabaseReference

Gpr26 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 5.5
p value: 2.81505311339288E-11
refers to: Gpr26

Csrnp1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 0.0467882407608608
refers to: Csrnp1

Wipi1
type: EnsemblDatabaseReference

Gm13716
type: EnsemblDatabaseReference

Gm16315
type: EnsemblDatabaseReference

Hspa1b
type: EnsemblDatabaseReference

Ovol2
type: EnsemblDatabaseReference

B3galnt1
type: EnsemblDatabaseReference

Syce2
type: EnsemblDatabaseReference

Reg3a
type: EnsemblDatabaseReference

Gcsh UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.00493220561700315
refers to: Gcsh

Hopx
type: EnsemblDatabaseReference

D10Bwg1379e
type: EnsemblDatabaseReference

Cntn3 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.2
p value: 0.0216964119121513
refers to: Cntn3

Tph1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 5.9
p value: 1.68144382530212E-46
refers to: Tph1

Ngfr UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.0104710750900271
refers to: Ngfr

Gbp8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.8
p value: 8.72065289765743E-4
refers to: Gbp8

Prlr UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 2.87299290434763E-10
refers to: Prlr

Fmo1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 4.0
p value: 5.63585220093248E-40
refers to: Fmo1

Bmp1
type: EnsemblDatabaseReference

(Factor value) CLINICAL_INFORMATION/pregnant
type: EFO_0000001
property type: CLINICAL_INFORMATION
property value: pregnant

Fmo4
type: EnsemblDatabaseReference

Lonrf3 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.8
p value: 6.92323540179201E-6
refers to: Lonrf3

Lonrf3
type: EnsemblDatabaseReference

Npas4 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -2.1
p value: 8.13429517785864E-11
refers to: Npas4

(Sample) age/13
type: EFO_0000001
property type: age
property value: 13

Igfbp5
type: EnsemblDatabaseReference

Grp
type: EnsemblDatabaseReference

Socs2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 1.76120406094131E-5
refers to: Socs2

Cldn8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 5.5
p value: 5.92906772735136E-47
refers to: Cldn8

Pcsk1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.00176675862339163
refers to: Pcsk1

Ehhadh
type: EnsemblDatabaseReference

Rgs2 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.9
p value: 2.08524664820447E-13
refers to: Rgs2

Ehhadh UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.6
p value: 1.96074774795623E-13
refers to: Ehhadh

Sftpd
type: EnsemblDatabaseReference

Gm17040
type: EnsemblDatabaseReference

Reg3b
type: EnsemblDatabaseReference

Dnmt3b
type: EnsemblDatabaseReference

Mctp1
type: EnsemblDatabaseReference

Tsc22d3
type: EnsemblDatabaseReference

Itga6
type: EnsemblDatabaseReference

Wipi1
type: EnsemblDatabaseReference

Chgb
type: EnsemblDatabaseReference

Ikzf4
type: EnsemblDatabaseReference

D5Ertd579e
type: EnsemblDatabaseReference

Mus musculus
type: OBI_0100026

Znrf2
type: EnsemblDatabaseReference

Dnajb1
type: EnsemblDatabaseReference

Gm27168
type: EnsemblDatabaseReference

Slc40a1
type: EnsemblDatabaseReference

Vip
type: EnsemblDatabaseReference

Disp2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 1.25548927318942E-8
refers to: Disp2

(Sample) developmental stage/adult
type: EFO_0001272
property type: developmental stage
property value: adult

Enpp2
type: EnsemblDatabaseReference

Nr4a1
type: EnsemblDatabaseReference

Cux2
type: EnsemblDatabaseReference

Mdm1
type: EnsemblDatabaseReference

Hsph1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0
p value: 7.23231529238154E-5
refers to: Hsph1

Tph2
type: EnsemblDatabaseReference

Tph2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.9
p value: 2.5944268484991E-4
refers to: Tph2

Ivd
type: EnsemblDatabaseReference

mt-Rnr2
type: EnsemblDatabaseReference

Cartpt
type: EnsemblDatabaseReference

Prok1
type: EnsemblDatabaseReference

Dusp1
type: EnsemblDatabaseReference

Ogdhl
type: EnsemblDatabaseReference

Nupr1
type: EnsemblDatabaseReference

Junb
type: EnsemblDatabaseReference

1110038B12Rik
type: EnsemblDatabaseReference

Rab3d
type: EnsemblDatabaseReference

Tph1
type: EnsemblDatabaseReference

Lonrf3
type: EnsemblDatabaseReference

Prlr
type: EnsemblDatabaseReference

Ggact
type: EnsemblDatabaseReference

Hapln4
type: EnsemblDatabaseReference

Acvr1c
type: EnsemblDatabaseReference

Txnrd2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1
p value: 4.88620200973633E-5
refers to: Txnrd2

Dnmt3b UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 0.0168050041565101
refers to: Dnmt3b

(Assay) SRR054660
type: Assay

Derl3
type: EnsemblDatabaseReference

(Assay) SRR054662
type: Assay

Grhl1
type: EnsemblDatabaseReference

Ogdhl UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.9
p value: 1.24567189315039E-17
refers to: Ogdhl

Prkd1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 0.0250391046533975
refers to: Prkd1

Tnfrsf11b UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.4
p value: 1.22083632393415E-9
refers to: Tnfrsf11b

Txnrd2
type: EnsemblDatabaseReference

Glp1r
type: EnsemblDatabaseReference

Tnfrsf11b
type: EnsemblDatabaseReference

Gbp8
type: EnsemblDatabaseReference

Sptbn2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0129861649308266
refers to: Sptbn2

Itga6 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.019709549113708
refers to: Itga6

Cux2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.00493220561700315
refers to: Cux2

Igfals
type: EnsemblDatabaseReference

D630039A03Rik UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.00740533699219425
refers to: D630039A03Rik

Rnf182
type: EnsemblDatabaseReference

(Sample) clinical history/13 to 15 days post conception
type: EFO_0000001
property type: clinical history
property value: 13 to 15 days post conception

Gpr26
type: EnsemblDatabaseReference

Pcsk1
type: EnsemblDatabaseReference

Reg3d
type: EnsemblDatabaseReference

Sdf2l1
type: EnsemblDatabaseReference

1110038B12Rik DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7
p value: 0.0206555008899512
refers to: 1110038B12Rik

Hsbp1
type: EnsemblDatabaseReference

Cartpt UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.3
p value: 0.0104710750900271
refers to: Cartpt

D5Ertd579e
type: EnsemblDatabaseReference

Kirrel3 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.4
p value: 0.039208128328829
refers to: Kirrel3

Znrf2
type: EnsemblDatabaseReference

Gm27168 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 5.4
p value: 3.95531539419632E-14
refers to: Gm27168

Gatm
type: EnsemblDatabaseReference

Synpr UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.2
p value: 1.25518711859424E-5
refers to: Synpr

Gm16314 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.4
p value: 0.00740533699219425
refers to: Gm16314

Bmp1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 1.05208251119514E-4
refers to: Bmp1

Cux2
type: EnsemblDatabaseReference

Hspa1a
type: EnsemblDatabaseReference

Pycr1
type: EnsemblDatabaseReference

Bsn
type: EnsemblDatabaseReference

Fkbp11
type: EnsemblDatabaseReference

Csrnp1
type: EnsemblDatabaseReference

Kirrel3os
type: EnsemblDatabaseReference

Tsc22d3 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.0170452722979342
refers to: Tsc22d3

Aldh9a1
type: EnsemblDatabaseReference

Lrrc55
type: EnsemblDatabaseReference

Dnah8
type: EnsemblDatabaseReference

Prok1
type: EnsemblDatabaseReference

Lactbl1
type: EnsemblDatabaseReference

Gyltl1b UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.0175324701300384
refers to: Gyltl1b

mt-Rnr2 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -2.1
p value: 6.16856492553616E-4
refers to: mt-Rnr2

1300002E11Rik UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 0.00275377007113856
refers to: 1300002E11Rik

1300002E11Rik
type: EnsemblDatabaseReference

Hapln4 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.019220846844009
refers to: Hapln4

Slc2a13
type: EnsemblDatabaseReference

Junb DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 1.18185434254825E-5
refers to: Junb

Ggact
type: EnsemblDatabaseReference

Slc6a8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 3.93288998506605E-4
refers to: Slc6a8

Hsbp1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 1.79256765400307E-9
refers to: Hsbp1

Mctp1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.4
p value: 0.00138769149302532
refers to: Mctp1

Cttnbp2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 0.00168849079458859
refers to: Cttnbp2

Map6 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0475882666857675
refers to: Map6

Disp2
type: EnsemblDatabaseReference

Map6
type: EnsemblDatabaseReference

Apobec1
type: EnsemblDatabaseReference

(Assay) SRR054659
type: Assay

(Assay) SRR054664
type: Assay

Tmem255a
type: EnsemblDatabaseReference

Serinc5
type: EnsemblDatabaseReference

Prkd1
type: EnsemblDatabaseReference

Rnf150
type: EnsemblDatabaseReference

Neb
type: EnsemblDatabaseReference

(Sample) age/12
type: EFO_0000001
property type: age
property value: 12

Hspa1b
type: EnsemblDatabaseReference

Tmem255a UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.3
p value: 9.37498222192619E-13
refers to: Tmem255a

Ovol2
type: EnsemblDatabaseReference

Rnf182
type: EnsemblDatabaseReference

Slc6a8
type: EnsemblDatabaseReference

Reg3a
type: EnsemblDatabaseReference

Cntn3
type: EnsemblDatabaseReference

Aqp4
type: EnsemblDatabaseReference

D10Bwg1379e
type: EnsemblDatabaseReference

Matn2
type: EnsemblDatabaseReference

Gabbr2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 8.22001916038682E-5
refers to: Gabbr2

Syce2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.0
p value: 0.0299905325745422
refers to: Syce2

Fosb
type: EnsemblDatabaseReference

(Sample) organism part/pancreatic islet
type: UBERON_0000006
property type: organism part
property value: pancreatic islet

Ngfr
type: EnsemblDatabaseReference

Dnaja1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4
p value: 6.7766639698925E-6
refers to: Dnaja1

Rab3d UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 9.9661528711597E-5
refers to: Rab3d

Arc
type: EnsemblDatabaseReference

Bmp1
type: EnsemblDatabaseReference

Lrp8
type: EnsemblDatabaseReference

Sptbn2
type: EnsemblDatabaseReference

Lgals12
type: EnsemblDatabaseReference

Gabbr2
type: EnsemblDatabaseReference

Dhcr7
type: EnsemblDatabaseReference

Igfbp5 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 1.80499496055981E-5
refers to: Igfbp5

Nupr1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 4.42174503550237E-5
refers to: Nupr1

Reg3d UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 0.00188913432409285
refers to: Reg3d

Cspg5
type: EnsemblDatabaseReference

Grp
type: EnsemblDatabaseReference

Lactbl1
type: EnsemblDatabaseReference

Cish
type: EnsemblDatabaseReference

D630039A03Rik
type: EnsemblDatabaseReference

D10Bwg1379e UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.0454188151052671
refers to: D10Bwg1379e

Ehhadh
type: EnsemblDatabaseReference

Gcsh
type: EnsemblDatabaseReference

(Sample) age/14
type: EFO_0000001
property type: age
property value: 14

D5Ertd579e UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.0121383353952603
refers to: D5Ertd579e

Nr4a1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3
p value: 1.25041459445169E-6
refers to: Nr4a1

Gm17040
type: EnsemblDatabaseReference

(Sample) clinical information/pregnant
type: EFO_0000001
property type: clinical information
property value: pregnant

Apobec1
type: EnsemblDatabaseReference

Analysis of 'non-pregnant' vs 'pregnant'
type: RNASeqDifferentialAnalysis

(Sample) strain/C57BL/6J
type: EFO_0000606
property type: strain
property value: C57BL/6J

Crispld2
type: EnsemblDatabaseReference

Dnmt3b
type: EnsemblDatabaseReference

Cldn8
type: EnsemblDatabaseReference

Npas4
type: EnsemblDatabaseReference

Tsc22d3
type: EnsemblDatabaseReference

Arc DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.0216964119121513
refers to: Arc

Grhl1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.0
p value: 0.0078431400988123
refers to: Grhl1

Itga6
type: EnsemblDatabaseReference

Fmo1
type: EnsemblDatabaseReference

Ikzf4
type: EnsemblDatabaseReference

Aldh9a1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 2.21409058637049E-4
refers to: Aldh9a1

Car8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 9.61774544568751E-5
refers to: Car8

Rnf150 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 4.6349611817643E-4
refers to: Rnf150

Enpp2
type: EnsemblDatabaseReference

Nr4a1
type: EnsemblDatabaseReference

Mdm1
type: EnsemblDatabaseReference

Tph2
type: EnsemblDatabaseReference

Aldh1l2
type: EnsemblDatabaseReference

Fam155a
type: EnsemblDatabaseReference

Ngfr
type: EnsemblDatabaseReference

Ikzf4 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.3
p value: 1.16909141925407E-7
refers to: Ikzf4

Lrrc55 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 6.0
p value: 1.40400246296155E-24
refers to: Lrrc55

Kirrel3
type: EnsemblDatabaseReference

Cartpt
type: EnsemblDatabaseReference

Ogdhl
type: EnsemblDatabaseReference

Lrp8
type: EnsemblDatabaseReference

Gas2
type: EnsemblDatabaseReference

Cttnbp2
type: EnsemblDatabaseReference

Gas2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 4.46204636366089E-4
refers to: Gas2

Dhcr7
type: EnsemblDatabaseReference

Tph1
type: EnsemblDatabaseReference

Ern1
type: EnsemblDatabaseReference

Prlr
type: EnsemblDatabaseReference

Gm16315 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 0.00330837136275118
refers to: Gm16315

(Sample) clinical information/non-pregnant
type: EFO_0000001
property type: clinical information
property value: non-pregnant

Glp1r UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0169850912102401
refers to: Glp1r

Igfals UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 4.7846494704969E-8
refers to: Igfals

Chst11
type: EnsemblDatabaseReference

Socs2
type: EnsemblDatabaseReference

Reg3a UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.4
p value: 2.9938297828783E-9
refers to: Reg3a

Chgb UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.4
p value: 9.22857324812476E-32
refers to: Chgb

Acvr1c
type: EnsemblDatabaseReference

Aqp4 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.9
p value: 6.92323540179201E-6
refers to: Aqp4

Matn2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.9
p value: 1.19257042347131E-29
refers to: Matn2

Ovol2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1
p value: 1.91566797398161E-5
refers to: Ovol2

Rgs2
type: EnsemblDatabaseReference

Derl3
type: EnsemblDatabaseReference

(Assay) SRR054661
type: Assay

Znrf2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 6.60760068643073E-5
refers to: Znrf2

Sdf2l1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.00329520190678549
refers to: Sdf2l1

Prok1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: Infinity
p value: 0.00269510686231172
refers to: Prok1

Crispld2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.0340304173386425
refers to: Crispld2

Cspg5 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.7
p value: 3.93891777320964E-6
refers to: Cspg5

Gm16315
type: EnsemblDatabaseReference

Cish UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.7
p value: 9.49552158642734E-27
refers to: Cish

Tnfrsf11b
type: EnsemblDatabaseReference

Enpp2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 9.52467938323512E-9
refers to: Enpp2

Sftpd UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.6
p value: 1.27443875556757E-8
refers to: Sftpd

Syce2
type: EnsemblDatabaseReference

Igfals
type: EnsemblDatabaseReference

Dnah8 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.7
p value: 2.6413873702841E-9
refers to: Dnah8

Dhcr7 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 6.18137205468944E-6
refers to: Dhcr7

Hsph1
type: EnsemblDatabaseReference

Gpr26
type: EnsemblDatabaseReference

Pcsk1
type: EnsemblDatabaseReference

Reg3d
type: EnsemblDatabaseReference

Sdf2l1
type: EnsemblDatabaseReference

Aldh1l2 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.031590482069712
refers to: Aldh1l2

Fmo4 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.7
p value: 0.00670194727951628
refers to: Fmo4

Mdm1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 0.00138252487315493
refers to: Mdm1

Synpr
type: EnsemblDatabaseReference

Fmo4
type: EnsemblDatabaseReference

Hspa1a
type: EnsemblDatabaseReference

Pycr1
type: EnsemblDatabaseReference

Bsn
type: EnsemblDatabaseReference

E-GEOD-21860
type: rnaseq mrna differential
RO_0002162: Mus musculus
description: During pregnancy, the energy requirements of the fetus impose changes in maternal metabolism. Increasing insulin resistance in the mother maintains nutrient flow to the growing fetus, while prolactin and placental lactogen counterbalance this resistance and prevent maternal hyperglycemia by driving expansion of the maternal population of insulin-producing beta-cells. However, the exact mechanisms by which the lactogenic hormones drive beta-cell expansion remain uncertain. Here we show that serotonin acts downstream of lactogen signaling to drive beta-cell proliferation. Serotonin synthetic enzyme Tph1 and serotonin production increased sharply in beta-cells during pregnancy or after treatment with lactogens in vitro. Inhibition of serotonin synthesis by dietary tryptophan restriction or Tph inhibition blocked beta-cell expansion and induced glucose intolerance in pregnant mice without affecting insulin sensitivity. Expression of the Gq-linked serotonin receptor Htr2b in maternal islets increased during pregnancy and normalized just prior to parturition, while expression of the Gi-linked receptor Htr1d increased at the end of pregnancy and postpartum. Blocking Htr2b signaling in pregnant mice also blocked beta-cell expansion and caused glucose intolerance. These studies reveal an integrated signaling pathway linking beta-cell mass to anticipated insulin need during pregnancy. Modulators of this pathway, including medications and diet, may affect the risk of gestational diabetes. Analysis of poly(A)+ RNA from 3 biological replicates of pancreatic islets isolated from normal female and pregnant female mice
uses data from: http://identifiers.org/pubmed/20581837

Igfbp5
type: EnsemblDatabaseReference

Kirrel3os
type: EnsemblDatabaseReference

Lrrc55
type: EnsemblDatabaseReference

Dnah8
type: EnsemblDatabaseReference

Cttnbp2
type: EnsemblDatabaseReference

Sftpd
type: EnsemblDatabaseReference

1300002E11Rik
type: EnsemblDatabaseReference

Bsn UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 0.0460316733455848
refers to: Bsn

Slc2a13
type: EnsemblDatabaseReference

Ivd UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.9
p value: 2.69924885228936E-41
refers to: Ivd

Fosb DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2
p value: 0.00856831187833923
refers to: Fosb

Gyltl1b
type: EnsemblDatabaseReference

Disp2
type: EnsemblDatabaseReference

(Assay) SRR054663
type: Assay

Dnaja1
type: EnsemblDatabaseReference

Mctp1
type: EnsemblDatabaseReference

Chgb
type: EnsemblDatabaseReference

Serinc5
type: EnsemblDatabaseReference

Prkd1
type: EnsemblDatabaseReference

Rnf150
type: EnsemblDatabaseReference

Vip UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.8
p value: 1.02870739149812E-10
refers to: Vip

Neb
type: EnsemblDatabaseReference

Dnajb1
type: EnsemblDatabaseReference

Gm27168
type: EnsemblDatabaseReference

Slc40a1
type: EnsemblDatabaseReference

Hsph1
type: EnsemblDatabaseReference

Vip
type: EnsemblDatabaseReference

Neb UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.6
p value: 3.19668554137123E-25
refers to: Neb

Slc6a8
type: EnsemblDatabaseReference

Rnf182 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.0
p value: 9.12443830341495E-5
refers to: Rnf182

Hspa1a DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5
p value: 1.26323657002205E-7
refers to: Hspa1a

Cntn3
type: EnsemblDatabaseReference

(Sample) sex/female
type: EFO_0001265
property type: sex
property value: female

Chst11 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.00384314440008762
refers to: Chst11

Aqp4
type: EnsemblDatabaseReference

Matn2
type: EnsemblDatabaseReference

Gatm UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.0177641764111819
refers to: Gatm

Kirrel3os UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.7
p value: 5.07828905587744E-5
refers to: Kirrel3os

Ivd
type: EnsemblDatabaseReference

mt-Rnr2
type: EnsemblDatabaseReference

Serinc5 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0
p value: 0.00670255345470009
refers to: Serinc5

Fosb
type: EnsemblDatabaseReference

Hopx UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4
p value: 1.51987392523458E-4
refers to: Hopx

Ern1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2
p value: 6.92323540179201E-6
refers to: Ern1

Slc2a13 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.6
p value: 0.00740533699219425
refers to: Slc2a13

Dnajb1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5
p value: 2.9938297828783E-9
refers to: Dnajb1

Dusp1
type: EnsemblDatabaseReference

Nupr1
type: EnsemblDatabaseReference

Junb
type: EnsemblDatabaseReference

Synpr
type: EnsemblDatabaseReference

1110038B12Rik
type: EnsemblDatabaseReference

Arc
type: EnsemblDatabaseReference

Gm13716 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 3.5
p value: 1.70851161764761E-6
refers to: Gm13716

Rab3d
type: EnsemblDatabaseReference

Sptbn2
type: EnsemblDatabaseReference

Lgals12
type: EnsemblDatabaseReference

Hapln4
type: EnsemblDatabaseReference

Lgals12 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 0.0151840886958209
refers to: Lgals12

Gabbr2
type: EnsemblDatabaseReference

Car8
type: EnsemblDatabaseReference

Cspg5
type: EnsemblDatabaseReference

Cish
type: EnsemblDatabaseReference

D630039A03Rik
type: EnsemblDatabaseReference

Grhl1
type: EnsemblDatabaseReference

Gcsh
type: EnsemblDatabaseReference

Gm16314
type: EnsemblDatabaseReference

Gyltl1b
type: EnsemblDatabaseReference

Acvr1c UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.2
p value: 0.00368728755952496
refers to: Acvr1c

Txnrd2
type: EnsemblDatabaseReference

Glp1r
type: EnsemblDatabaseReference

Gbp8
type: EnsemblDatabaseReference

Gm13716
type: EnsemblDatabaseReference

Grp UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1
p value: 0.0349803775325561
refers to: Grp

Dnaja1
type: EnsemblDatabaseReference

B3galnt1
type: EnsemblDatabaseReference

B3galnt1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.7
p value: 3.34823216105345E-8
refers to: B3galnt1

Crispld2
type: EnsemblDatabaseReference

Fam155a UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 2.49516539465435E-4
refers to: Fam155a

Hopx
type: EnsemblDatabaseReference

Wipi1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.9
p value: 2.72775655882824E-13
refers to: Wipi1

Slc40a1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1
p value: 0.00270311903448025
refers to: Slc40a1

Cldn8
type: EnsemblDatabaseReference

Fkbp11 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 6.16856492553616E-4
refers to: Fkbp11

Npas4
type: EnsemblDatabaseReference

Gm17040 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 5.2
p value: 4.6349611817643E-4
refers to: Gm17040

Hsbp1
type: EnsemblDatabaseReference

Dusp1 DOWN in 'non-pregnant' vs 'pregnant'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1
p value: 6.56771197959729E-5
refers to: Dusp1

Fmo1
type: EnsemblDatabaseReference

Reg3b UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 2.5
p value: 1.66077275773418E-14
refers to: Reg3b

Gatm
type: EnsemblDatabaseReference

Derl3 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3
p value: 0.0499779684511534
refers to: Derl3

Apobec1 UP in 'non-pregnant' vs 'pregnant'
type: IncreasedDifferentialExpressionRatio
fold change: 1.5
p value: 1.73180956656613E-4
refers to: Apobec1

Csrnp1
type: EnsemblDatabaseReference

Aldh1l2
type: EnsemblDatabaseReference

Fkbp11
type: EnsemblDatabaseReference

Aldh9a1
type: EnsemblDatabaseReference

Fam155a
type: EnsemblDatabaseReference