(Assay) GSM520626
type: Assay
has participant: A-AFFY-44

HCCS
type: EnsemblDatabaseReference

MARCH3
type: EnsemblDatabaseReference

210407_at
type: EFO_0005072
part of: A-AFFY-44

AKTIP
type: EnsemblDatabaseReference

PLEKHA3 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13932604785559
p value: 0.00864205630635332
refers to: PLEKHA3
refers to: 223370_at
t statistic: -7.39665816357337

203745_at
type: EFO_0005072
part of: A-AFFY-44

QKI UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11603633587397
p value: 0.00927281884048372
refers to: 228540_at
refers to: QKI
t statistic: 7.19064294612261

225159_s_at
type: EFO_0005072
part of: A-AFFY-44

SGPP1
type: EnsemblDatabaseReference

OXR1
type: EnsemblDatabaseReference

RNH1
type: EnsemblDatabaseReference

Analysis of 'pre-miR-17' vs 'control pre-miR'
type: MicroarrayDifferentialExpressionAnalysis

NKIRAS1
type: EnsemblDatabaseReference

ERLIN2
type: EnsemblDatabaseReference

ZBTB41
type: EnsemblDatabaseReference

DOK5 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03750797710759
p value: 0.0148102320998458
refers to: DOK5
refers to: 214844_s_at
t statistic: 5.52311332413233

CDC37L1
type: EnsemblDatabaseReference

TGFBR2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19695933367627
p value: 0.0290639080561576
refers to: 207334_s_at
refers to: TGFBR2
t statistic: -4.14266291863413

CFL2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.02484563383001
p value: 0.00923705673592981
refers to: CFL2
refers to: 224663_s_at
t statistic: -7.20945719344948

PCDH17 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08351308228452
p value: 0.0112370094402176
refers to: PCDH17
refers to: 227289_at
t statistic: 6.22352301974366

213256_at
type: EFO_0005072
part of: A-AFFY-44

JAK1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.33909636284571
p value: 0.00864205630635332
refers to: JAK1
refers to: 1552611_a_at
t statistic: -8.49968650752028

AKTIP DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06084554377959
p value: 0.0192706927251385
refers to: 218373_at
refers to: AKTIP
t statistic: -4.89652399422208

KIT
type: EnsemblDatabaseReference

M6PR DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.11920109226979
p value: 0.0103976498735258
refers to: M6PR
refers to: 200900_s_at
t statistic: -6.78670043169757

LINC00116
type: EnsemblDatabaseReference

EFCAB14
type: EnsemblDatabaseReference

AKTIP
type: EnsemblDatabaseReference

(Assay) GSM520625
type: Assay
has participant: A-AFFY-44

M6PR
type: EnsemblDatabaseReference

218373_at
type: EFO_0005072
part of: A-AFFY-44

BMP4
type: EnsemblDatabaseReference

LCOR
type: EnsemblDatabaseReference

DAZAP2
type: EnsemblDatabaseReference

226979_at
type: EFO_0005072
part of: A-AFFY-44

TGFBR2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.170414501622
p value: 0.00864205630635332
refers to: TGFBR2
refers to: 208944_at
t statistic: -7.63693162914684

CMTR2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08502309256184
p value: 0.0398332097594398
refers to: CMTR2
refers to: 222811_at
t statistic: -3.67045940033157

225411_at
type: EFO_0005072
part of: A-AFFY-44

PLEKHA3
type: EnsemblDatabaseReference

ALDH1A1 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02937113703978
p value: 0.00864205630635332
refers to: ALDH1A1
refers to: 212224_at
t statistic: 8.45693780882666

EIF5A2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.31565948899833
p value: 0.0156129626885145
refers to: EIF5A2
refers to: 235289_at
t statistic: -5.3184175464352

HDHD1
type: EnsemblDatabaseReference

MOB1A DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04849762879248
p value: 0.0155624448397073
refers to: 201297_s_at
refers to: MOB1A
t statistic: -5.41784551325021

LPAR1
type: EnsemblDatabaseReference

PPM1A
type: EnsemblDatabaseReference

225856_at
type: EFO_0005072
part of: A-AFFY-44

HMGCS1
type: EnsemblDatabaseReference

227506_at
type: EFO_0005072
part of: A-AFFY-44

CDC37L1
type: EnsemblDatabaseReference

214831_at
type: EFO_0005072
part of: A-AFFY-44

M6PR DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.11658019642269
p value: 0.0103976498735258
refers to: 200901_s_at
refers to: M6PR
t statistic: -6.76483890675092

MAP3K2
type: EnsemblDatabaseReference

MKRN1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03525855631462
p value: 0.0127160316476846
refers to: 201285_at
refers to: MKRN1
t statistic: -5.96948553291397

228540_at
type: EFO_0005072
part of: A-AFFY-44

TSPAN8 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.05744130765343
p value: 0.0426222061140037
refers to: TSPAN8
refers to: 203824_at
t statistic: 3.59776968480229

RASSF2
type: EnsemblDatabaseReference

227395_at
type: EFO_0005072
part of: A-AFFY-44

CFL2
type: EnsemblDatabaseReference

PAPPA
type: EnsemblDatabaseReference

PAPPA UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.12376594034152
p value: 0.0103976498735258
refers to: PAPPA
refers to: 224941_at
t statistic: 6.9307837878781

224663_s_at
type: EFO_0005072
part of: A-AFFY-44

202381_at
type: EFO_0005072
part of: A-AFFY-44

204595_s_at
type: EFO_0005072
part of: A-AFFY-44

OXR1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08712581336976
p value: 0.0109107857360255
refers to: 218197_s_at
refers to: OXR1
t statistic: -6.39245497314535

STC1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27369831738371
p value: 0.0295314960013065
refers to: 204595_s_at
refers to: STC1
t statistic: -4.10753893438443

SGPP1
type: EnsemblDatabaseReference

200900_s_at
type: EFO_0005072
part of: A-AFFY-44

(Factor value) RNA_INTERFERENCE/control pre-miR
type: EFO_0000001
property type: RNA_INTERFERENCE
property value: control pre-miR

1555326_a_at
type: EFO_0005072
part of: A-AFFY-44

GNPDA2
type: EnsemblDatabaseReference

224399_at
type: EFO_0005072
part of: A-AFFY-44

FZD5
type: EnsemblDatabaseReference

TBC1D9
type: EnsemblDatabaseReference

214844_s_at
type: EFO_0005072
part of: A-AFFY-44

218287_s_at
type: EFO_0005072
part of: A-AFFY-44

218231_at
type: EFO_0005072
part of: A-AFFY-44

SMIM14 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09532593309009
p value: 0.032646688347138
refers to: 227052_at
refers to: SMIM14
t statistic: -3.95726059890661

NKIRAS1
type: EnsemblDatabaseReference

SGPL1
type: EnsemblDatabaseReference

ERLIN2
type: EnsemblDatabaseReference

ANKRD46
type: EnsemblDatabaseReference

GPR137B DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.10871480969619
p value: 0.0109107857360255
refers to: GPR137B
refers to: 204137_at
t statistic: -6.37462134436771

JAK1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.39014677915009
p value: 0.0103976498735258
refers to: 201648_at
refers to: JAK1
t statistic: -6.8241564631985

CFL2
type: EnsemblDatabaseReference

210896_s_at
type: EFO_0005072
part of: A-AFFY-44

223734_at
type: EFO_0005072
part of: A-AFFY-44

KIT
type: EnsemblDatabaseReference

ERLIN2 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.26074787065925
p value: 0.00864205630635332
refers to: ERLIN2
refers to: 221542_s_at
t statistic: 7.66207723375963

TMEM87B UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03893227163142
p value: 0.00864205630635332
refers to: TMEM87B
refers to: 225411_at
t statistic: 7.4784886398284

LINC00116
type: EnsemblDatabaseReference

238761_at
type: EFO_0005072
part of: A-AFFY-44

200901_s_at
type: EFO_0005072
part of: A-AFFY-44

M6PR
type: EnsemblDatabaseReference

LCOR
type: EnsemblDatabaseReference

KIT DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12086718245062
p value: 0.0128933671524607
refers to: KIT
refers to: 205051_s_at
t statistic: -5.92947094999523

GNPDA2
type: EnsemblDatabaseReference

TMEM19 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00073511419873
p value: 0.0089089594026496
refers to: TMEM19
refers to: 229126_at
t statistic: -7.30787642173766

208944_at
type: EFO_0005072
part of: A-AFFY-44

DAZAP2
type: EnsemblDatabaseReference

225974_at
type: EFO_0005072
part of: A-AFFY-44

ADAM9 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.39701633295922
p value: 0.0159348051904989
refers to: ADAM9
refers to: 202381_at
t statistic: -5.27149413723222

(Sample) cell type/umbilical vein endothelial cell
type: EFO_0000001
property type: cell type
property value: umbilical vein endothelial cell

SLC16A9 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12805786541625
p value: 0.0287488845662887
refers to: 227506_at
refers to: SLC16A9
t statistic: -4.16429639132954

FZD5
type: EnsemblDatabaseReference

TBC1D9
type: EnsemblDatabaseReference

HDHD1
type: EnsemblDatabaseReference

SGPL1
type: EnsemblDatabaseReference

206050_s_at
type: EFO_0005072
part of: A-AFFY-44

ASPH
type: EnsemblDatabaseReference

LPAR1
type: EnsemblDatabaseReference

PPM1A
type: EnsemblDatabaseReference

EFCAB14 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17780276571021
p value: 0.0196465760248007
refers to: 201776_s_at
refers to: EFCAB14
t statistic: -4.85905514105452

203870_at
type: EFO_0005072
part of: A-AFFY-44

201776_s_at
type: EFO_0005072
part of: A-AFFY-44

ELK4 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14866738913637
p value: 0.0109107857360255
refers to: ELK4
refers to: 238761_at
t statistic: -6.3153731857585

PCDH17 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.17265421542916
p value: 0.0202567309238337
refers to: PCDH17
refers to: 228863_at
t statistic: 4.79892006642668

TMEM87B
type: EnsemblDatabaseReference

(Assay) GSM520624
type: Assay
has participant: A-AFFY-44

1552610_a_at
type: EFO_0005072
part of: A-AFFY-44

202016_at
type: EFO_0005072
part of: A-AFFY-44

RASSF2
type: EnsemblDatabaseReference

229027_at
type: EFO_0005072
part of: A-AFFY-44

CLOCK
type: EnsemblDatabaseReference

MGARP
type: EnsemblDatabaseReference

HCCS DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04585943720638
p value: 0.0138281417763498
refers to: HCCS
refers to: 203745_at
t statistic: -5.6461084528317

HDHD1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12805790561951
p value: 0.00864205630635332
refers to: 203974_at
refers to: HDHD1
t statistic: -8.40121197848829

GBP3 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.52688522822856
p value: 0.0155624448397073
refers to: GBP3
refers to: 223434_at
t statistic: -5.34377132532534

USP46
type: EnsemblDatabaseReference

AGO1
type: EnsemblDatabaseReference

EIF5A2
type: EnsemblDatabaseReference

202478_at
type: EFO_0005072
part of: A-AFFY-44

227514_at
type: EFO_0005072
part of: A-AFFY-44

ADAM9 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.37464192297018
p value: 0.0218483978975024
refers to: 1555326_a_at
refers to: ADAM9
t statistic: -4.61680223181462

LPAR1 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01730724554841
p value: 0.0156129626885145
refers to: LPAR1
refers to: 204036_at
t statistic: 5.31842556740489

227531_at
type: EFO_0005072
part of: A-AFFY-44

C7orf60
type: EnsemblDatabaseReference

212224_at
type: EFO_0005072
part of: A-AFFY-44

SGPP1 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.09917592538301
p value: 0.0423803999827348
refers to: SGPP1
refers to: 221268_s_at
t statistic: 3.60409803689839

CLOCK DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.07995755717341
p value: 0.0146396892011088
refers to: CLOCK
refers to: 227531_at
t statistic: -5.56141265389949

1552611_a_at
type: EFO_0005072
part of: A-AFFY-44

PPM1A DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12413428914556
p value: 0.0263039920828689
refers to: 229027_at
refers to: PPM1A
t statistic: -4.3134032701636

223370_at
type: EFO_0005072
part of: A-AFFY-44

ANKRD46
type: EnsemblDatabaseReference

(Assay) GSM520629
type: Assay
has participant: A-AFFY-44

HMGCS1 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.07377407274121
p value: 0.0164998730795236
refers to: 205822_s_at
refers to: HMGCS1
t statistic: 5.18254015629492

204137_at
type: EFO_0005072
part of: A-AFFY-44

DOK5
type: EnsemblDatabaseReference

NAGK DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.28322607405391
p value: 0.0109107857360255
refers to: 218231_at
refers to: NAGK
t statistic: -6.41751636919982

SMIM14 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.43406823049522
p value: 0.00864205630635332
refers to: 224989_at
refers to: SMIM14
t statistic: -7.5949304693173

MALAT1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.10303127833849
p value: 0.0103976498735258
refers to: MALAT1
refers to: 223940_x_at
t statistic: -6.73270010956938

CLOCK
type: EnsemblDatabaseReference

228614_at
type: EFO_0005072
part of: A-AFFY-44

MGARP
type: EnsemblDatabaseReference

GIPC2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.71667813111065
p value: 0.0223148180689306
refers to: GIPC2
refers to: 236548_at
t statistic: -4.57904899876787

ERLIN2 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.00277168432789
p value: 0.0147585947187974
refers to: ERLIN2
refers to: 221543_s_at
t statistic: 5.53818551449527

ZBTB41 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15658292418367
p value: 0.0367172582130206
refers to: ZBTB41
refers to: 226962_at
t statistic: -3.77274675580096

PDCD1LG2
type: EnsemblDatabaseReference

HMGCS1 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08593364694227
p value: 0.0117520269396561
refers to: HMGCS1
refers to: 221750_at
t statistic: 6.09915760478605

MALAT1
type: EnsemblDatabaseReference

USP46
type: EnsemblDatabaseReference

EIF5A2
type: EnsemblDatabaseReference

KATNAL1
type: EnsemblDatabaseReference

GBP3
type: EnsemblDatabaseReference

RASSF2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.01304997578276
p value: 0.00864205630635332
refers to: 203185_at
refers to: RASSF2
t statistic: -7.93915570902659

204604_at
type: EFO_0005072
part of: A-AFFY-44

C7orf60
type: EnsemblDatabaseReference

PPM1A DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00644832803376
p value: 0.00864205630635332
refers to: PPM1A
refers to: 210407_at
t statistic: -9.92985933903062

MAP3K2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14638488621799
p value: 0.0136625257119009
refers to: MAP3K2
refers to: 226979_at
t statistic: -5.67273005905324

209135_at
type: EFO_0005072
part of: A-AFFY-44

CDC37L1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22488967512852
p value: 0.00864205630635332
refers to: CDC37L1
refers to: 219343_at
t statistic: -7.64606326358919

ASPH
type: EnsemblDatabaseReference

235289_at
type: EFO_0005072
part of: A-AFFY-44

RNF41 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13988806847274
p value: 0.0109107857360255
refers to: RNF41
refers to: 235459_at
t statistic: 6.29129940943595

AGO1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17155489998462
p value: 0.0104468067990776
refers to: AGO1
refers to: 218287_s_at
t statistic: -6.69395256245971

RNF149
type: EnsemblDatabaseReference

FYCO1
type: EnsemblDatabaseReference

224989_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM520627
type: Assay
has participant: A-AFFY-44

TMEM87B
type: EnsemblDatabaseReference

218197_s_at
type: EFO_0005072
part of: A-AFFY-44

227289_at
type: EFO_0005072
part of: A-AFFY-44

ELK4 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08565186314372
p value: 0.00864205630635332
refers to: 214831_at
refers to: ELK4
t statistic: -8.15039537019438

227022_at
type: EFO_0005072
part of: A-AFFY-44

TSPAN8
type: EnsemblDatabaseReference

DAZAP2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03897881738951
p value: 0.0109107857360255
refers to: DAZAP2
refers to: 200794_x_at
t statistic: -6.37232671044315

219343_at
type: EFO_0005072
part of: A-AFFY-44

219970_at
type: EFO_0005072
part of: A-AFFY-44

204036_at
type: EFO_0005072
part of: A-AFFY-44

STC1
type: EnsemblDatabaseReference

AGO1
type: EnsemblDatabaseReference

226962_at
type: EFO_0005072
part of: A-AFFY-44

TMEM19
type: EnsemblDatabaseReference

212956_at
type: EFO_0005072
part of: A-AFFY-44

235459_at
type: EFO_0005072
part of: A-AFFY-44

ALDH1A1
type: EnsemblDatabaseReference

GIPC2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.580435150632
p value: 0.0187213802910342
refers to: GIPC2
refers to: 219970_at
t statistic: -4.9498811857556

GPR137B
type: EnsemblDatabaseReference

FYCO1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.84307217049882
p value: 0.00864205630635332
refers to: FYCO1
refers to: 218204_s_at
t statistic: -7.4213402462858

CDK14 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02056469407248
p value: 0.0109107857360255
refers to: 204604_at
refers to: CDK14
t statistic: 6.34841965404525

USP46 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.37834413828151
p value: 0.00864205630635332
refers to: 203870_at
refers to: USP46
t statistic: -7.57958830718487

ANKRD46 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.14298051586262
p value: 0.00864205630635332
refers to: 212731_at
refers to: ANKRD46
t statistic: 7.74549222632988

RNF149
type: EnsemblDatabaseReference

FYCO1
type: EnsemblDatabaseReference

ASPH UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02316606994806
p value: 0.0175809507924105
refers to: ASPH
refers to: 209135_at
t statistic: 5.07599917665172

Homo sapiens
type: OBI_0100026

TBCEL
type: EnsemblDatabaseReference

225414_at
type: EFO_0005072
part of: A-AFFY-44

DOK5
type: EnsemblDatabaseReference

229126_at
type: EFO_0005072
part of: A-AFFY-44

221542_s_at
type: EFO_0005072
part of: A-AFFY-44

224942_at
type: EFO_0005072
part of: A-AFFY-44

MEST UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.46393964163298
p value: 0.0221810481322348
refers to: MEST
refers to: 202016_at
t statistic: 4.59317660581781

JAK1
type: EnsemblDatabaseReference

212731_at
type: EFO_0005072
part of: A-AFFY-44

NAGK
type: EnsemblDatabaseReference

218204_s_at
type: EFO_0005072
part of: A-AFFY-44

PDCD1LG2
type: EnsemblDatabaseReference

MALAT1
type: EnsemblDatabaseReference

224940_s_at
type: EFO_0005072
part of: A-AFFY-44

TMEM64 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.21482334384431
p value: 0.0143746548756169
refers to: TMEM64
refers to: 225972_at
t statistic: -5.58477686047159

205822_s_at
type: EFO_0005072
part of: A-AFFY-44

ALDH1A1
type: EnsemblDatabaseReference

201297_s_at
type: EFO_0005072
part of: A-AFFY-44

MKRN1
type: EnsemblDatabaseReference

KATNAL1
type: EnsemblDatabaseReference

LCOR DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08285285871754
p value: 0.0166709608648649
refers to: LCOR
refers to: 228454_at
t statistic: -5.14908647452759

PCDH17
type: EnsemblDatabaseReference

GBP3
type: EnsemblDatabaseReference

A-AFFY-44
type: EFO_0000269

TGFB2
type: EnsemblDatabaseReference

MGARP UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.24042587481039
p value: 0.0104468067990776
refers to: 223734_at
refers to: MGARP
t statistic: 6.71676528320628

BMP4 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02455699846447
p value: 0.0273512246709881
refers to: BMP4
refers to: 211518_s_at
t statistic: 4.24200794255739

225972_at
type: EFO_0005072
part of: A-AFFY-44

201285_at
type: EFO_0005072
part of: A-AFFY-44

ITPRIPL2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.01384953041023
p value: 0.0135416537599049
refers to: ITPRIPL2
refers to: 227514_at
t statistic: -5.69797139155712

TGFBR2
type: EnsemblDatabaseReference

222811_at
type: EFO_0005072
part of: A-AFFY-44

236548_at
type: EFO_0005072
part of: A-AFFY-44

GIPC2
type: EnsemblDatabaseReference

GNPDA2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16446091885286
p value: 0.0187164897493678
refers to: GNPDA2
refers to: 227022_at
t statistic: -4.95859448977637

201648_at
type: EFO_0005072
part of: A-AFFY-44

TSPAN8
type: EnsemblDatabaseReference

JAK1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1801785987545
p value: 0.0227991595587727
refers to: 1552610_a_at
refers to: JAK1
t statistic: -4.5344401570657

KATNAL1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17092423429417
p value: 0.0128933671524607
refers to: KATNAL1
refers to: 227713_at
t statistic: -5.92612477750837

CMTR2
type: EnsemblDatabaseReference

(Factor value) RNA_INTERFERENCE/pre-miR-17
type: EFO_0000001
property type: RNA_INTERFERENCE
property value: pre-miR-17

CFL2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16876972117917
p value: 0.0186733528275285
refers to: CFL2
refers to: 224352_s_at
t statistic: -4.96842234304497

PDCD1LG2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08109590326784
p value: 0.0134592737466743
refers to: PDCD1LG2
refers to: 220049_s_at
t statistic: -5.82274046598742

STC1
type: EnsemblDatabaseReference

TMEM19
type: EnsemblDatabaseReference

MOB1A
type: EnsemblDatabaseReference

LINC00116 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.48803746517042
p value: 0.0117772345377002
refers to: LINC00116
refers to: 228614_at
t statistic: -6.05947629254434

222453_at
type: EFO_0005072
part of: A-AFFY-44

ITPRIPL2
type: EnsemblDatabaseReference

MEST
type: EnsemblDatabaseReference

GPR137B
type: EnsemblDatabaseReference

TGFBR2
type: EnsemblDatabaseReference

TMEM64
type: EnsemblDatabaseReference

TBCEL
type: EnsemblDatabaseReference

ELK4
type: EnsemblDatabaseReference

PAPPA UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08018000608314
p value: 0.00864205630635332
refers to: PAPPA
refers to: 224940_s_at
t statistic: 8.70931220901959

GIPC2
type: EnsemblDatabaseReference

CLOCK DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16339362652934
p value: 0.00864205630635332
refers to: CLOCK
refers to: 225856_at
t statistic: -7.48286889847392

RNF41
type: EnsemblDatabaseReference

228121_at
type: EFO_0005072
part of: A-AFFY-44

ADAM9
type: EnsemblDatabaseReference

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

228149_at
type: EFO_0005072
part of: A-AFFY-44

CMTR2
type: EnsemblDatabaseReference

228863_at
type: EFO_0005072
part of: A-AFFY-44

JAK1
type: EnsemblDatabaseReference

224941_at
type: EFO_0005072
part of: A-AFFY-44

TMEM64 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06928219337905
p value: 0.0109107857360255
refers to: TMEM64
refers to: 225974_at
t statistic: -6.39650523685724

NAGK
type: EnsemblDatabaseReference

224352_s_at
type: EFO_0005072
part of: A-AFFY-44

RNH1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16480951862263
p value: 0.0129786960263169
refers to: 206050_s_at
refers to: RNH1
t statistic: -5.87942455737655

TRIB2 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.25259983542657
p value: 0.0103976498735258
refers to: TRIB2
refers to: 202478_at
t statistic: 6.8936450008056

MKRN1
type: EnsemblDatabaseReference

MEST
type: EnsemblDatabaseReference

PCDH17
type: EnsemblDatabaseReference

SLC16A9
type: EnsemblDatabaseReference

FZD5 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.39001095231996
p value: 0.00864205630635332
refers to: FZD5
refers to: 221245_s_at
t statistic: 8.61262903939178

TGFB2
type: EnsemblDatabaseReference

203824_at
type: EFO_0005072
part of: A-AFFY-44

211518_s_at
type: EFO_0005072
part of: A-AFFY-44

TMEM64
type: EnsemblDatabaseReference

223434_at
type: EFO_0005072
part of: A-AFFY-44

212322_at
type: EFO_0005072
part of: A-AFFY-44

200794_x_at
type: EFO_0005072
part of: A-AFFY-44

203185_at
type: EFO_0005072
part of: A-AFFY-44

C7orf60 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.64149045539675
p value: 0.0135416537599049
refers to: C7orf60
refers to: 228149_at
t statistic: -5.70390303977492

MOB1A DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.07433238995589
p value: 0.00864205630635332
refers to: MOB1A
refers to: 201298_s_at
t statistic: -7.38160344412229

CYBRD1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7381339770537
p value: 0.0213865845173884
refers to: CYBRD1
refers to: 222453_at
t statistic: -4.67758280078753

TBCEL DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17478288290751
p value: 0.0134592737466743
refers to: TBCEL
refers to: 227395_at
t statistic: -5.80499002494197

225930_at
type: EFO_0005072
part of: A-AFFY-44

220049_s_at
type: EFO_0005072
part of: A-AFFY-44

QKI
type: EnsemblDatabaseReference

227052_at
type: EFO_0005072
part of: A-AFFY-44

HCCS
type: EnsemblDatabaseReference

MARCH3
type: EnsemblDatabaseReference

(Assay) GSM520628
type: Assay
has participant: A-AFFY-44

TGFB2 UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.05081802437433
p value: 0.0156082442194524
refers to: TGFB2
refers to: 228121_at
t statistic: 5.33264828642399

221268_s_at
type: EFO_0005072
part of: A-AFFY-44

SGPL1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00243676980372
p value: 0.0103976498735258
refers to: SGPL1
refers to: 212322_at
t statistic: -6.740540943372

SMIM14
type: EnsemblDatabaseReference

SLC16A9
type: EnsemblDatabaseReference

PDCD1LG2 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.32366034031807
p value: 0.0151572647972911
refers to: 224399_at
refers to: PDCD1LG2
t statistic: -5.47467980791353

MOB1A
type: EnsemblDatabaseReference

207334_s_at
type: EFO_0005072
part of: A-AFFY-44

ELK4 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.37326798113297
p value: 0.0164998730795236
refers to: 225159_s_at
refers to: ELK4
t statistic: -5.1893345317005

RNH1
type: EnsemblDatabaseReference

ITPRIPL2
type: EnsemblDatabaseReference

CDK14
type: EnsemblDatabaseReference

ZBTB41
type: EnsemblDatabaseReference

PAPPA UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.05822112290681
p value: 0.0103976498735258
refers to: PAPPA
refers to: 224942_at
t statistic: 6.75699001701221

221543_s_at
type: EFO_0005072
part of: A-AFFY-44

203974_at
type: EFO_0005072
part of: A-AFFY-44

TRIB2
type: EnsemblDatabaseReference

CYBRD1
type: EnsemblDatabaseReference

ELK4
type: EnsemblDatabaseReference

205051_s_at
type: EFO_0005072
part of: A-AFFY-44

TBC1D9 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08820087458384
p value: 0.00864205630635332
refers to: 212956_at
refers to: TBC1D9
t statistic: -7.6217412002579

EFCAB14
type: EnsemblDatabaseReference

NKIRAS1 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05676364521499
p value: 0.00864205630635332
refers to: NKIRAS1
refers to: 225930_at
t statistic: -7.3653508057944

RNF41
type: EnsemblDatabaseReference

221245_s_at
type: EFO_0005072
part of: A-AFFY-44

227713_at
type: EFO_0005072
part of: A-AFFY-44

ADAM9
type: EnsemblDatabaseReference

201298_s_at
type: EFO_0005072
part of: A-AFFY-44

BMP4
type: EnsemblDatabaseReference

ASPH UP in 'pre-miR-17' vs 'control pre-miR'
type: IncreasedDifferentialExpressionRatio
fold change: 1.35139612407197
p value: 0.00864205630635332
refers to: 210896_s_at
refers to: ASPH
t statistic: 9.08771069804041

MARCH3 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.34584500172592
p value: 0.00864205630635332
refers to: MARCH3
refers to: 213256_at
t statistic: -7.81692408549126

SMIM14
type: EnsemblDatabaseReference

PLEKHA3
type: EnsemblDatabaseReference

E-GEOD-20745
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: MicroRNAs are endogenously expressed small non-coding RNAs that regulate gene expression on the posttranscriptional level. The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia. Whereas miR-92a was recently identified as negative regulator of angiogenesis, the specific functions of the other members of the cluster are less clear. Here we demonstrate that overexpression of miR-17, -18a, -19a and -20a significantly inhibited 3D spheroid sprouting in vitro, whereas inhibition of miR-17, -18a and -20a augmented endothelial cell (EC) sprout formation. Inhibition of miR-17 and miR-20a in vivo using antagomirs significantly increased the number of perfused vessels in matrigel plugs, whereas antagomirs, that specifically target miR-18a and miR-19a were less effective. However, systemic inhibition of miR-17/20 did not affect tumor angiogenesis. Further mechanistic studies showed that miR-17/20 targets several pro-angiogenic genes. Specifically, Janus kinase 1 (Jak1) was shown to be a direct target of miR-17. In summary, we show that miR-17/20 exhibit a cell intrinsic anti-angiogenic activity in ECs. Inhibition of miR-17/20 specifically augmented neovascularization of matrigel plugs, but did not affect tumor angiogenesis indicating a context-dependent regulation of angiogenesis by miR-17/20 in vivo. 6 samples of 3 independent experiments (n=3): per experiment Pre-miR-Co (10 nM, Ambion) and Pre-miR-17 (10 nM, Ambion) transfected HUVEC 24h after transfection
uses data from: http://identifiers.org/pubmed/20299512

221750_at
type: EFO_0005072
part of: A-AFFY-44

LCOR DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.10881700817604
p value: 0.0155624448397073
refers to: LCOR
refers to: 226520_at
t statistic: -5.35120741123357

RNF149 DOWN in 'pre-miR-17' vs 'control pre-miR'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2563261609673
p value: 0.0211904941023348
refers to: 225414_at
refers to: RNF149
t statistic: -4.70220830953959

226520_at
type: EFO_0005072
part of: A-AFFY-44

CDK14
type: EnsemblDatabaseReference

228454_at
type: EFO_0005072
part of: A-AFFY-44

OXR1
type: EnsemblDatabaseReference

HMGCS1
type: EnsemblDatabaseReference

TRIB2
type: EnsemblDatabaseReference

CYBRD1
type: EnsemblDatabaseReference

MAP3K2
type: EnsemblDatabaseReference

PAPPA
type: EnsemblDatabaseReference

223940_x_at
type: EFO_0005072
part of: A-AFFY-44

QKI
type: EnsemblDatabaseReference