GALNT16
type: EnsemblDatabaseReference

DUSP4
type: EnsemblDatabaseReference

GALNT16
type: EnsemblDatabaseReference

(Assay) GSM506915
type: Assay
has participant: A-AFFY-44

DUSP4 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 2.50135010453421
p value: 0.0254510742753332
refers to: 226034_at
refers to: DUSP4
t statistic: 4.94580923883731

228518_at
type: EFO_0005072
part of: A-AFFY-44

EGR1
type: EnsemblDatabaseReference

217826_s_at
type: EFO_0005072
part of: A-AFFY-44

221563_at
type: EFO_0005072
part of: A-AFFY-44

SLC16A6 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.12445885113241
p value: 0.0423997198147728
refers to: SLC16A6
refers to: 230748_at
t statistic: 4.12064932335721

Analysis of '2 micromolar LMP-420' vs 'none'
type: MicroarrayDifferentialExpressionAnalysis

215501_s_at
type: EFO_0005072
part of: A-AFFY-44

209374_s_at
type: EFO_0005072
part of: A-AFFY-44

IGHM
type: EnsemblDatabaseReference

204014_at
type: EFO_0005072
part of: A-AFFY-44

IGHM
type: EnsemblDatabaseReference

A-AFFY-44
type: EFO_0000269

204015_s_at
type: EFO_0005072
part of: A-AFFY-44

LY9
type: EnsemblDatabaseReference

(Assay) GSM506925
type: Assay
has participant: A-AFFY-44

TNFRSF17
type: EnsemblDatabaseReference

(Assay) GSM506921
type: Assay
has participant: A-AFFY-44

TNFRSF17
type: EnsemblDatabaseReference

(Assay) GSM506912
type: Assay
has participant: A-AFFY-44

LRRC32
type: EnsemblDatabaseReference

214933_at
type: EFO_0005072
part of: A-AFFY-44

CACNA1A
type: EnsemblDatabaseReference

203835_at
type: EFO_0005072
part of: A-AFFY-44

EGR1 DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.60012108998913
p value: 0.0307841312422802
refers to: EGR1
refers to: 201694_s_at
t statistic: -4.41239471259166

CACNA1A
type: EnsemblDatabaseReference

LDLRAD4
type: EnsemblDatabaseReference

(Assay) GSM506922
type: Assay
has participant: A-AFFY-44

SLC16A6
type: EnsemblDatabaseReference

LDLRAD4
type: EnsemblDatabaseReference

LDLRAD4 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11155542088901
p value: 0.0496372385341084
refers to: LDLRAD4
refers to: 209574_s_at
t statistic: 3.93470553415848

UBE2J1 DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.02375061677477
p value: 0.0307841312422802
refers to: 217823_s_at
refers to: UBE2J1
t statistic: -4.40607410957985

EGR1
type: EnsemblDatabaseReference

(Assay) GSM506918
type: Assay
has participant: A-AFFY-44

UBE2J1
type: EnsemblDatabaseReference

UBE2J1
type: EnsemblDatabaseReference

231124_x_at
type: EFO_0005072
part of: A-AFFY-44

CACNA1A DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.46899260029145
p value: 0.0258790724124608
refers to: 214933_at
refers to: CACNA1A
t statistic: -4.57966945353452

(Assay) GSM506931
type: Assay
has participant: A-AFFY-44

SESN3
type: EnsemblDatabaseReference

SESN3
type: EnsemblDatabaseReference

(Assay) GSM506926
type: Assay
has participant: A-AFFY-44

FOSL2 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 2.25798510803595
p value: 0.0350264004459285
refers to: FOSL2
refers to: 228188_at
t statistic: 4.30913428330016

GALNT16 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02314368410823
p value: 0.0496372385341084
refers to: GALNT16
refers to: 230418_s_at
t statistic: 3.92879319049508

201694_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506924
type: Assay
has participant: A-AFFY-44

LY9
type: EnsemblDatabaseReference

226034_at
type: EFO_0005072
part of: A-AFFY-44

Homo sapiens
type: OBI_0100026

(Assay) GSM506914
type: Assay
has participant: A-AFFY-44

225262_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506909
type: Assay
has participant: A-AFFY-44

(Assay) GSM506916
type: Assay
has participant: A-AFFY-44

DUSP10
type: EnsemblDatabaseReference

SESN3 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.25149752763867
p value: 0.0431369519797817
refers to: SESN3
refers to: 242899_at
t statistic: 4.09281050668114

DUSP10
type: EnsemblDatabaseReference

SLC16A6
type: EnsemblDatabaseReference

LY9 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.22306061661237
p value: 0.0354569742843853
refers to: LY9
refers to: 231124_x_at
t statistic: 4.27243065258847

(Assay) GSM506911
type: Assay
has participant: A-AFFY-44

215967_s_at
type: EFO_0005072
part of: A-AFFY-44

242899_at
type: EFO_0005072
part of: A-AFFY-44

LY9 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1781753445196
p value: 0.0254510742753332
refers to: LY9
refers to: 210370_s_at
t statistic: 4.67541617450315

(Assay) GSM506929
type: Assay
has participant: A-AFFY-44

209574_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506917
type: Assay
has participant: A-AFFY-44

LY9 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13009085372732
p value: 0.0258790724124608
refers to: LY9
refers to: 215967_s_at
t statistic: 4.57841567706036

FOSL2
type: EnsemblDatabaseReference

FOSL2
type: EnsemblDatabaseReference

206641_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506919
type: Assay
has participant: A-AFFY-44

230748_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506907
type: Assay
has participant: A-AFFY-44

LRRC32 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.78626075314277
p value: 0.0254510742753332
refers to: LRRC32
refers to: 203835_at
t statistic: 5.17096254529973

IGHG1
type: EnsemblDatabaseReference

IGHG1
type: EnsemblDatabaseReference

(Assay) GSM506927
type: Assay
has participant: A-AFFY-44

(Sample) cell type/chronic lymphocytic leukemia cell
type: EFO_0000095
property type: cell type
property value: chronic lymphocytic leukemia cell

(Assay) GSM506910
type: Assay
has participant: A-AFFY-44

210370_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506932
type: Assay
has participant: A-AFFY-44

DUSP10 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.22040000584566
p value: 0.0254510742753332
refers to: DUSP10
refers to: 215501_s_at
t statistic: 4.76169479345133

235684_s_at
type: EFO_0005072
part of: A-AFFY-44

230418_s_at
type: EFO_0005072
part of: A-AFFY-44

SESN3 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.25475580544745
p value: 0.0350264004459285
refers to: 235683_at
refers to: SESN3
t statistic: 4.29455046361905

FOSL2 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 2.66088560313686
p value: 0.0258790724124608
refers to: 225262_at
refers to: FOSL2
t statistic: 4.55253093364515

DUSP4
type: EnsemblDatabaseReference

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

228188_at
type: EFO_0005072
part of: A-AFFY-44

(Factor value) COMPOUND/LMP-420 2
type: EFO_0000001
property type: COMPOUND
property value: LMP-420 2

235683_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506923
type: Assay
has participant: A-AFFY-44

DUSP10 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3970245171639
p value: 0.0254510742753332
refers to: DUSP10
refers to: 221563_at
t statistic: 4.92426970118268

SESN3 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.18274162624361
p value: 0.0290880595961715
refers to: SESN3
refers to: 235684_s_at
t statistic: 4.48249334011314

(Assay) GSM506908
type: Assay
has participant: A-AFFY-44

DUSP4 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 2.11462903662476
p value: 0.0258790724124608
refers to: 204015_s_at
refers to: DUSP4
t statistic: 4.61602459687613

(Assay) GSM506920
type: Assay
has participant: A-AFFY-44

TNFRSF17 DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -2.20872214004867
p value: 0.0354569742843853
refers to: 206641_at
refers to: TNFRSF17
t statistic: -4.26199267971596

DUSP4 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 3.05733165040901
p value: 0.0254510742753332
refers to: DUSP4
refers to: 204014_at
t statistic: 5.01233442784315

IGHM DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22827282891902
p value: 0.0307841312422802
refers to: IGHM
refers to: 209374_s_at
t statistic: -4.40852381384925

218880_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506913
type: Assay
has participant: A-AFFY-44

(Assay) GSM506928
type: Assay
has participant: A-AFFY-44

(Factor value) COMPOUND/none
type: EFO_0001461
property type: COMPOUND
property value: none

IGHG1 DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08933903372438
p value: 0.0254510742753332
refers to: IGHG1
refers to: 228518_at
t statistic: -5.22812959024768

217823_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM506930
type: Assay
has participant: A-AFFY-44

LRRC32
type: EnsemblDatabaseReference

E-GEOD-20211
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: [original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and minimal toxicity for normal hematopoietic cells. LMP-420 induces cytotoxicity and apoptosis to CLL cells in vitro without any negative effects to normal immune cells. This gene expression experiment compares CLL cells treated with LMP-420 versus media alone to investigate the mechanism of action of LMP-420. CLL cells from 13 patients were treated with LMP-420 or media for 24 hours, then RNA was extracted and assayed on U133Plus2 GeneChips.
uses data from: http://identifiers.org/pubmed/20613784

UBE2J1 DOWN in '2 micromolar LMP-420' vs 'none'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09343372951575
p value: 0.0254510742753332
refers to: 217826_s_at
refers to: UBE2J1
t statistic: -4.67506216236109

FOSL2 UP in '2 micromolar LMP-420' vs 'none'
type: IncreasedDifferentialExpressionRatio
fold change: 1.43143291178268
p value: 0.0496372385341084
refers to: 218880_at
refers to: FOSL2
t statistic: 3.98617266891598