ETNPPL UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
S100A10 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
HPGD UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
EFNB2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
S100A6 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
RAB25 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MYL9 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FLNA DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SCAMP1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SPINT1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MAT1A UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NINJ2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
BGN DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ICAM2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TSPAN8 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GJA1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CDH17 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GPX2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PTGER2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
S100P UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ADH6 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AP1M2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SUCLG2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PDE3B DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
BNIP3L DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NYNRIN DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SWAP70 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SPP1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AREG DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
THBS1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CEBPD UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ETNK1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SALL1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
REG3A UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PRODH2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LUM DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ENPP4 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PRSS3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LGALS3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FLRT2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GPR37 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SLC19A3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SLC7A11 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TAGLN DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SH2B3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GCNT1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SERPINE1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
Analysis of 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NRCAM DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GALNT3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ZNF395 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GULP1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
F2RL1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PKLR UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
(Sample) disease/hepatocellular carcinoma
CTSH UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ATP6V0E2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NT5E UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
DNAJC12 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
RHOBTB1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PGAM2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FZD2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
HP UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MXRA8 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PMP22 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
IL32 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
C19orf80 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AMOTL2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TNFAIP8 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
UCHL1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FAM134B DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SSBP2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TIMP1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SOBP DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CRIM1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GPNMB UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MCM9 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NES DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LARP6 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ITGA1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
S100A4 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
KRT23 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FILIP1L DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SPINK1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
(Factor value) GENOTYPE/wild type genotype
HABP2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NPDC1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PTPLA UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
OSBPL10 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LPHN3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
RARRES2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
COL2A1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
Overexpression of LSF in less aggressive hepatocellular carcinoma (HCC) cells resulted in highly aggressive, angiogenic and multi-organ metastatic tumors while inhibition of LSF significantly abrogated growth and metastasis of highly aggressive HCC cells in nude mice. We used microarrays to identify the downstream genes mediating the effects of LSF in HCC cells. Gene expression profiles were compared between Control-8 and LSF-17 clones of HepG3 cells.
TM4SF4 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PLK2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
(Factor value) GENOTYPE/Late SV40 Factor (LSF) over expression
TSPYL4 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AKAP12 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TBX3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
RAB40B DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GBP1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
STEAP1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
RGS10 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ARHGEF3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NAV2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CCDC69 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CA2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
IFT74 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
THBS4 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
TFCP2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CYP2B6 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FRY DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CAPN2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PKIG DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LEF1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LANCL1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ATP2B4 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
LGALS1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
BCAT1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FMO1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ENO3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SPON2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AASS DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
REG1A UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ESRP1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PHGDH UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
NAT8 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GUCY2C UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FGFR2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PLAC8 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MANEA DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SLC7A9 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PEG3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
WLS DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SH3BGRL DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SFN UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GPR56 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GBA3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SCGN UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SLC26A3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
HOMER3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MCOLN3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SI UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CD74 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
FABP1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
HOXA10 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
DLK1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SERPINA10 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SLCO1B3 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
EEF1A2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SULT1C2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
(Sample) genotype/Late SV40 Factor (LSF) over expression
ADAM28 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SNN DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
APPL1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
HAMP UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MICAL2 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ABCG2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MUC13 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
GOLM1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MAF UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PBX1 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PCDH7 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
DEFB1 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ANXA3 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
IGFBP7 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
UGT8 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CFH UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CNTNAP2 UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
PCSK5 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
MYO10 DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
CAST DOWN in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
SEMA6A UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
ASNS UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'
AADAC UP in 'Late SV40 Factor (LSF) over expression' vs 'wild type'