Analysis of 'ERRa knock out' vs 'wild type'
Cyp2d9 UP in 'ERRa knock out' vs 'wild type'
Igkc UP in 'ERRa knock out' vs 'wild type'
Igj UP in 'ERRa knock out' vs 'wild type'
Col1a1 DOWN in 'ERRa knock out' vs 'wild type'
Cadm4 UP in 'ERRa knock out' vs 'wild type'
Car3 UP in 'ERRa knock out' vs 'wild type'
Neurog2 UP in 'ERRa knock out' vs 'wild type'
Cyp2d12 UP in 'ERRa knock out' vs 'wild type'
Unc13b UP in 'ERRa knock out' vs 'wild type'
(Factor value) GENOTYPE/wild type genotype
Esrra DOWN in 'ERRa knock out' vs 'wild type'
Cdk1 DOWN in 'ERRa knock out' vs 'wild type'
Cyp2f2 UP in 'ERRa knock out' vs 'wild type'
Apoe UP in 'ERRa knock out' vs 'wild type'
Dbp UP in 'ERRa knock out' vs 'wild type'
Klk1b5 DOWN in 'ERRa knock out' vs 'wild type'
Col3a1 DOWN in 'ERRa knock out' vs 'wild type'
Estrogen-related receptor (ERR) alpha is an orphan nuclear receptor highly expressed in the kidneys. ERRalpha is implicated in renal sodium and potassium homeostasis and blood pressure regulation. We used microarray analysis to identify differentially expressed genes in ERR alpha knockout mice kidneys versus wild-type. The results provide insight on the roles of ERRalpha in the kidney. Three biological replicates of WT and ERRaKO were performed, for a total of 6 samples. 2-3 month old males of each genotype were used.
Egr1 UP in 'ERRa knock out' vs 'wild type'
Igha UP in 'ERRa knock out' vs 'wild type'
Per2 UP in 'ERRa knock out' vs 'wild type'
Col5a2 DOWN in 'ERRa knock out' vs 'wild type'
Nefl UP in 'ERRa knock out' vs 'wild type'
Scd1 UP in 'ERRa knock out' vs 'wild type'
Top2a DOWN in 'ERRa knock out' vs 'wild type'
Atp4a UP in 'ERRa knock out' vs 'wild type'
Chd3os UP in 'ERRa knock out' vs 'wild type'
Azgp1 UP in 'ERRa knock out' vs 'wild type'
Cox8b UP in 'ERRa knock out' vs 'wild type'