Akap5 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Myh6 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Wnt2 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Analysis of 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Clip4 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Ms4a4d UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Fabp4 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Lrg1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Serpina3g UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Msmo1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Brix1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Pisd-ps1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Slc26a4 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
F13a1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
AU040972 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Ppp1r3c DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Tnnt2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Inmt UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Spp1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Scd1 DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Fmo2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Aldh1a1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Csrp3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Sod3 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Clca3 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Plcxd3 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
H19 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Crabp1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Myl7 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Idi1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Itih4 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Mid1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Igfbp3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Cd59a DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Chil4 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Chil3 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Clic5 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Fam107a UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Zbtb16 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Wif1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Cyp1a1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Fst UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Lcn2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Fgfr3 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Chia1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Cd59a DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Analysis of 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Marco UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Retnla UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Stfa2l1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Ttn UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Tnni3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Anp32a UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Hp UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Thbs3 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Myom2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Tchh DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Nfe2l2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
8430419K02Rik UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Fam198b UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Sema4f UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Gsta3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Gpx3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Nnt DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Sln UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Palmd UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Spink5 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Rbm3 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Dpep1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
A2m DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
2210011C24Rik UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
8430419K02Rik UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Asz1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Crh DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Ntrk2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Chia1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Tnnc1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Shisa3 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
(Factor value) GENOTYPE/wild type genotype
Cckar UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Rasgrf2 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Col4a4 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Frem1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
(Sample) genotype/FGFR3 and FGFR4 double heterozygous mutant
FGFR3 and FGFR4 double heterozygous mutant
Etv1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Analysis of 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
(Factor value) GENOTYPE/FGFR3 and FGFR4 double heterozygous mutant
Pid1 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Steap4 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Pdk4 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Ahnak2 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Tchh DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Chil3 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
A2m DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Mid2 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Dmkn UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Rbm39 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Slitrk6 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Gdf10 DOWN in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
(Sample) genotype/FGFR3 and FGFR4 double knockout
Gene expression profiling of newborn lung tissue revealed few changes in compound FGFR3/FGFR4 deficient mice, consistent with their normal lung morphology at birth, suggesting the sequence of events leading to the phenotype initiates after birth in this model. Profiling of 4 week-old lung tissues revealed an induction of genes related to elastic fiber assembly in compound mutants. Lung RNA isolated from three animals of each genotype-age group were pooled for each Affymetrix chip (n=3 chips for each, except n=2 for wild type at 4 weeks.
Igfbp2 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
(Factor value) GENOTYPE/FGFR3 and FGFR4 double knockout
Dlk1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Analysis of 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Scnn1b UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Cdk19 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Pcolce2 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Gdpd2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Ptpn5 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Mustn1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Tppp3 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Kcne2 DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Arg2 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Hck UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '1 day'
Mid1 UP in 'FGFR3 and FGFR4 double heterozygous mutant' vs 'wild type genotype' in '8 day'
Fkbp5 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
Spp1 UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'
A2m DOWN in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '1 day'
Clec4n UP in 'FGFR3 and FGFR4 double knockout' vs 'wild type genotype' in '8 day'