Aldoc DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22116224132064
p value: 0.0102272664488565
refers to: Aldoc
refers to: 1451461_a_at
t statistic: -4.80632112954431

Sgk1
type: EnsemblDatabaseReference

1418509_at
type: EFO_0005072
part of: A-AFFY-23

1426246_at
type: EFO_0005072
part of: A-AFFY-23

1419271_at
type: EFO_0005072
part of: A-AFFY-23

Eya2
type: EnsemblDatabaseReference

Nudt4
type: EnsemblDatabaseReference

1419456_at
type: EFO_0005072
part of: A-AFFY-23

Krt79
type: EnsemblDatabaseReference

1810011O10Rik UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.51075634920591
p value: 0.00168312761779166
refers to: 1810011O10Rik
refers to: 1451415_at
t statistic: 6.84130694559446

Gadd45g
type: EnsemblDatabaseReference

Cbr2
type: EnsemblDatabaseReference

Spry2
type: EnsemblDatabaseReference

Socs2
type: EnsemblDatabaseReference

1435697_a_at
type: EFO_0005072
part of: A-AFFY-23

Tmem47
type: EnsemblDatabaseReference

1434705_at
type: EFO_0005072
part of: A-AFFY-23

1420514_at
type: EFO_0005072
part of: A-AFFY-23

1434920_a_at
type: EFO_0005072
part of: A-AFFY-23

Akap12 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1836007750672
p value: 0.049530169621469
refers to: 1419706_a_at
refers to: Akap12
t statistic: -3.21832245880527

Prom1
type: EnsemblDatabaseReference

Kcnn4 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.11121191270428
p value: 0.0189001300281603
refers to: Kcnn4
refers to: 1435945_a_at
t statistic: -4.16367197617201

1450009_at
type: EFO_0005072
part of: A-AFFY-23

Krt19
type: EnsemblDatabaseReference

Abhd5
type: EnsemblDatabaseReference

Hspa1b
type: EnsemblDatabaseReference

1421381_a_at
type: EFO_0005072
part of: A-AFFY-23

1452257_at
type: EFO_0005072
part of: A-AFFY-23

Pip
type: EnsemblDatabaseReference

Rbp7
type: EnsemblDatabaseReference

Ddit4
type: EnsemblDatabaseReference

Analysis of 'Hunk knockout' vs 'wild type genotype'
type: MicroarrayDifferentialExpressionAnalysis

1416041_at
type: EFO_0005072
part of: A-AFFY-23

1419033_at
type: EFO_0005072
part of: A-AFFY-23

1423933_a_at
type: EFO_0005072
part of: A-AFFY-23

1450060_at
type: EFO_0005072
part of: A-AFFY-23

Acaa2
type: EnsemblDatabaseReference

Fam174b
type: EnsemblDatabaseReference

(Sample) genotype/Hunk knockout
type: EFO_0000001
property type: genotype
property value: Hunk knockout

Slc6a15
type: EnsemblDatabaseReference

Ctbp2
type: EnsemblDatabaseReference

1417045_at
type: EFO_0005072
part of: A-AFFY-23

A-AFFY-23
type: EFO_0000269

Sfrp2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.01928801755039
p value: 0.0112788448931125
refers to: Sfrp2
refers to: 1448201_at
t statistic: 4.72182965171834

Anxa1
type: EnsemblDatabaseReference

Fam3c
type: EnsemblDatabaseReference

Selenbp1
type: EnsemblDatabaseReference

1438245_at
type: EFO_0005072
part of: A-AFFY-23

1455490_at
type: EFO_0005072
part of: A-AFFY-23

1448201_at
type: EFO_0005072
part of: A-AFFY-23

1435446_a_at
type: EFO_0005072
part of: A-AFFY-23

(Factor value) GENOTYPE/Hunk knockout
type: EFO_0000001
property type: GENOTYPE
property value: Hunk knockout

Kit
type: EnsemblDatabaseReference

1449461_at
type: EFO_0005072
part of: A-AFFY-23

C3 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.28256062219237
p value: 0.0194509556780096
refers to: C3
refers to: 1423954_at
t statistic: 4.12394613485261

Slc28a3 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.44411252894646
p value: 0.0443601317386155
refers to: 1419571_at
refers to: Slc28a3
t statistic: 3.32779032167346

Elf5
type: EnsemblDatabaseReference

Nrep UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.04992747762777
p value: 0.0486488236728291
refers to: Nrep
refers to: 1450839_at
t statistic: 3.23572053961517

Sema3b
type: EnsemblDatabaseReference

St6galnac4
type: EnsemblDatabaseReference

1452106_at
type: EFO_0005072
part of: A-AFFY-23

Pip UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.65655908476681
p value: 0.0375314340827429
refers to: Pip
refers to: 1449212_at
t statistic: 3.47209393908528

1450699_at
type: EFO_0005072
part of: A-AFFY-23

1418075_at
type: EFO_0005072
part of: A-AFFY-23

Pax6
type: EnsemblDatabaseReference

Add3 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1422688782041
p value: 0.00192402166310332
refers to: Add3
refers to: 1423298_at
t statistic: 6.72305269559814

Pgd
type: EnsemblDatabaseReference

1417290_at
type: EFO_0005072
part of: A-AFFY-23

Evl DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.30996814191865
p value: 0.0471148380240571
refers to: Evl
refers to: 1434920_a_at
t statistic: -3.27508663588426

Hspa1b UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.401100151508
p value: 0.00521044027770734
refers to: Hspa1b
refers to: 1427127_x_at
t statistic: 5.52422796776125

Kit DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5769693497337
p value: 0.0275246402628642
refers to: Kit
refers to: 1452514_a_at
t statistic: -3.78440401974222

Bex1
type: EnsemblDatabaseReference

Prom1
type: EnsemblDatabaseReference

Pigr
type: EnsemblDatabaseReference

1418171_at
type: EFO_0005072
part of: A-AFFY-23

Mus musculus
type: OBI_0100026

(Sample) organism/Mus musculus
type: Mus musculus
property type: organism
property value: Mus musculus

1423954_at
type: EFO_0005072
part of: A-AFFY-23

Pip
type: EnsemblDatabaseReference

Rbp7
type: EnsemblDatabaseReference

Rhpn2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13120302732988
p value: 0.0176349081355183
refers to: 1434628_a_at
refers to: Rhpn2
t statistic: 4.22399779046025

Chn2
type: EnsemblDatabaseReference

Nr4a1
type: EnsemblDatabaseReference

1434628_a_at
type: EFO_0005072
part of: A-AFFY-23

Pgd UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01676893417602
p value: 0.00112940974374835
refers to: 1423706_a_at
refers to: Pgd
t statistic: 7.41207071065575

Ccl28 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.17725456420365
p value: 0.0165298997057371
refers to: 1450218_at
refers to: Ccl28
t statistic: 4.30803697633498

Thrsp
type: EnsemblDatabaseReference

1450218_at
type: EFO_0005072
part of: A-AFFY-23

1417089_a_at
type: EFO_0005072
part of: A-AFFY-23

1416129_at
type: EFO_0005072
part of: A-AFFY-23

1426712_at
type: EFO_0005072
part of: A-AFFY-23

Npnt DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.32482271810824
p value: 0.00353488979948307
refers to: Npnt
refers to: 1452106_at
t statistic: -5.90633067527233

Aldoc
type: EnsemblDatabaseReference

Sgk1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.66809075871191
p value: 0.00168312761779166
refers to: Sgk1
refers to: 1416041_at
t statistic: -6.85408484886231

Nupr1
type: EnsemblDatabaseReference

Fam3c
type: EnsemblDatabaseReference

(Assay) GSM356516
type: Assay
has participant: A-AFFY-23

1416505_at
type: EFO_0005072
part of: A-AFFY-23

1448595_a_at
type: EFO_0005072
part of: A-AFFY-23

Anxa1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.32187324030455
p value: 0.00217340062001463
refers to: 1448213_at
refers to: Anxa1
t statistic: 6.58708478165494

Duoxa1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.25561306235853
p value: 0.0171630576627695
refers to: Duoxa1
refers to: 1460372_at
t statistic: -4.2485141250876

Sfrp2
type: EnsemblDatabaseReference

1419555_at
type: EFO_0005072
part of: A-AFFY-23

Dcxr
type: EnsemblDatabaseReference

Pros1
type: EnsemblDatabaseReference

1435870_at
type: EFO_0005072
part of: A-AFFY-23

Errfi1
type: EnsemblDatabaseReference

Sema3b
type: EnsemblDatabaseReference

1419032_at
type: EFO_0005072
part of: A-AFFY-23

Add3 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.21934991977009
p value: 0.00100619404063469
refers to: 1426574_a_at
refers to: Add3
t statistic: 7.63706819637796

Bid
type: EnsemblDatabaseReference

Irs1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17658543523958
p value: 0.00358523103258377
refers to: Irs1
refers to: 1423104_at
t statistic: -5.87444583749643

1419700_a_at
type: EFO_0005072
part of: A-AFFY-23

Rhpn2
type: EnsemblDatabaseReference

Ltf
type: EnsemblDatabaseReference

Deptor
type: EnsemblDatabaseReference

Akap12
type: EnsemblDatabaseReference

Cytip
type: EnsemblDatabaseReference

Errfi1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14731943322786
p value: 0.00262158715526437
refers to: Errfi1
refers to: 1416129_at
t statistic: -6.33505432191899

Shf
type: EnsemblDatabaseReference

Pgd
type: EnsemblDatabaseReference

1435945_a_at
type: EFO_0005072
part of: A-AFFY-23

Fblim1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2612027365693
p value: 0.0179051769568788
refers to: Fblim1
refers to: 1418569_at
t statistic: -4.20957106376402

G0s2
type: EnsemblDatabaseReference

Chpt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.5386071594937
p value: 0.00112940974374835
refers to: Chpt1
refers to: 1426146_a_at
t statistic: 7.45135211760895

1454067_a_at
type: EFO_0005072
part of: A-AFFY-23

Tmem47 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.25387272594363
p value: 0.00457165965000949
refers to: Tmem47
refers to: 1420514_at
t statistic: -5.65436513701369

Bex2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27511423449099
p value: 0.0113023381596192
refers to: Bex2
refers to: 1417388_at
t statistic: -4.71541097444079

1428574_a_at
type: EFO_0005072
part of: A-AFFY-23

Irs1
type: EnsemblDatabaseReference

Sema3b DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.80997233470613
p value: 0.0281877421863322
refers to: Sema3b
refers to: 1448415_a_at
t statistic: -3.76237659729988

2610018G03Rik
type: EnsemblDatabaseReference

Fblim1
type: EnsemblDatabaseReference

1451206_s_at
type: EFO_0005072
part of: A-AFFY-23

Ccl28
type: EnsemblDatabaseReference

Emid1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.91874111154286
p value: 0.00521044027770734
refers to: Emid1
refers to: 1449581_at
t statistic: -5.47735974745819

Tmem47 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08776410381262
p value: 0.0125454271864533
refers to: Tmem47
refers to: 1449885_at
t statistic: -4.57782441331104

Abhd5 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.22859175371847
p value: 0.00348651682317897
refers to: Abhd5
refers to: 1417565_at
t statistic: 5.92865549164117

Dusp6
type: EnsemblDatabaseReference

Gadd45g UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.15868986241196
p value: 0.0033101059206366
refers to: Gadd45g
refers to: 1453851_a_at
t statistic: 6.0560693075478

4931406C07Rik
type: EnsemblDatabaseReference

Chdh
type: EnsemblDatabaseReference

1419665_a_at
type: EFO_0005072
part of: A-AFFY-23

Tceal8
type: EnsemblDatabaseReference

Thrsp UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.27385930598581
p value: 0.0375314340827429
refers to: Thrsp
refers to: 1422973_a_at
t statistic: 3.4721572714351

Socs2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.56936554889491
p value: 0.00162002647765672
refers to: Socs2
refers to: 1418507_s_at
t statistic: -6.90990495357869

1422973_a_at
type: EFO_0005072
part of: A-AFFY-23

1416455_a_at
type: EFO_0005072
part of: A-AFFY-23

Bdh1
type: EnsemblDatabaseReference

1418091_at
type: EFO_0005072
part of: A-AFFY-23

Grb10
type: EnsemblDatabaseReference

(Sample) genotype/wild type genotype
type: EFO_0000001
property type: genotype
property value: wild type genotype

Evl
type: EnsemblDatabaseReference

Duoxa1
type: EnsemblDatabaseReference

Rnf128 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02233598811597
p value: 0.00909174699063213
refers to: Rnf128
refers to: 1418318_at
t statistic: 4.93183227597824

Plet1
type: EnsemblDatabaseReference

Npnt
type: EnsemblDatabaseReference

Tfcp2l1
type: EnsemblDatabaseReference

Ckmt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.16969792246374
p value: 0.00353488979948307
refers to: 1432418_a_at
refers to: Ckmt1
t statistic: 5.8985682859728

1448700_at
type: EFO_0005072
part of: A-AFFY-23

1427127_x_at
type: EFO_0005072
part of: A-AFFY-23

Tmem30b
type: EnsemblDatabaseReference

Kcnn4
type: EnsemblDatabaseReference

Fgfr1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18645921296497
p value: 0.0204423894085372
refers to: 1424050_s_at
refers to: Fgfr1
t statistic: -4.09590266764483

(Factor value) GENOTYPE/wild type genotype
type: EFO_0000001
property type: GENOTYPE
property value: wild type genotype

(Assay) GSM356509
type: Assay
has participant: A-AFFY-23

Eya2
type: EnsemblDatabaseReference

Sfrp2
type: EnsemblDatabaseReference

Nudt4
type: EnsemblDatabaseReference

Krt79
type: EnsemblDatabaseReference

1427352_at
type: EFO_0005072
part of: A-AFFY-23

2610018G03Rik DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.79414969436503
p value: 0.00108975251628623
refers to: 2610018G03Rik
refers to: 1419032_at
t statistic: -7.54928302523176

1428146_s_at
type: EFO_0005072
part of: A-AFFY-23

Serpine2
type: EnsemblDatabaseReference

Thrsp UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.51424736663872
p value: 0.0443098403370645
refers to: Thrsp
refers to: 1424737_at
t statistic: 3.33235762706341

Errfi1
type: EnsemblDatabaseReference

Tmem30b UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03347754245909
p value: 0.00262158715526437
refers to: Tmem30b
refers to: 1433579_at
t statistic: 6.38440343968808

Gadd45g
type: EnsemblDatabaseReference

Cbr2
type: EnsemblDatabaseReference

1428571_at
type: EFO_0005072
part of: A-AFFY-23

1423706_a_at
type: EFO_0005072
part of: A-AFFY-23

1419706_a_at
type: EFO_0005072
part of: A-AFFY-23

Abhd5 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.31942545800533
p value: 0.0251109758706523
refers to: Abhd5
refers to: 1417566_at
t statistic: 3.86980067693982

1417388_at
type: EFO_0005072
part of: A-AFFY-23

Pros1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23807364996274
p value: 0.0389079548777508
refers to: Pros1
refers to: 1426246_at
t statistic: -3.44509006823468

Hp
type: EnsemblDatabaseReference

1455435_s_at
type: EFO_0005072
part of: A-AFFY-23

1436584_at
type: EFO_0005072
part of: A-AFFY-23

Krt19
type: EnsemblDatabaseReference

Cpd DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.08578881321996
p value: 0.0272448436550485
refers to: Cpd
refers to: 1418018_at
t statistic: -3.79530963455997

Hspa1b
type: EnsemblDatabaseReference

Glul
type: EnsemblDatabaseReference

Abhd5
type: EnsemblDatabaseReference

1417566_at
type: EFO_0005072
part of: A-AFFY-23

1423298_at
type: EFO_0005072
part of: A-AFFY-23

1810011O10Rik
type: EnsemblDatabaseReference

1415834_at
type: EFO_0005072
part of: A-AFFY-23

Emid1
type: EnsemblDatabaseReference

Col9a1
type: EnsemblDatabaseReference

Ddit4
type: EnsemblDatabaseReference

4931406C07Rik DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.44849091492195
p value: 0.0311860765916521
refers to: 1454067_a_at
refers to: 4931406C07Rik
t statistic: -3.64207664888159

(Sample) organism part/mammary gland
type: UBERON_0001911
property type: organism part
property value: mammary gland

Rnf128
type: EnsemblDatabaseReference

Krt19 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.61950813798287
p value: 0.00928178231116125
refers to: Krt19
refers to: 1417156_at
t statistic: 4.89932149789766

G0s2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.30471199301484
p value: 0.0386996428712342
refers to: G0s2
refers to: 1448700_at
t statistic: 3.44973566654818

Cryab UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.27206480295249
p value: 0.00868650367524412
refers to: 1434369_a_at
refers to: Cryab
t statistic: 5.00604403039648

Chdh UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.43478322820303
p value: 0.0033155075102047
refers to: Chdh
refers to: 1455435_s_at
t statistic: 6.01339055312899

Chdh
type: EnsemblDatabaseReference

Cpd
type: EnsemblDatabaseReference

Slc6a15
type: EnsemblDatabaseReference

Kcnn4 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09112213898685
p value: 0.0210915101188104
refers to: Kcnn4
refers to: 1421038_a_at
t statistic: -4.06199491006979

Fgfr1
type: EnsemblDatabaseReference

Dcxr UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.06578230663207
p value: 0.00379302251194561
refers to: 1419456_at
refers to: Dcxr
t statistic: 5.81813805339432

Dusp6 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.53352903956807
p value: 6.13621353017918E-4
refers to: 1415834_at
refers to: Dusp6
t statistic: -8.38468786973833

Cytip UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.21031897808741
p value: 0.00271903751035022
refers to: 1435697_a_at
refers to: Cytip
t statistic: 6.21349118074617

Glul UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.45480751776147
p value: 0.0169699001558525
refers to: Glul
refers to: 1426236_a_at
t statistic: 4.27023037223461

Npnt
type: EnsemblDatabaseReference

St6galnac4 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06118976407298
p value: 0.00521044027770734
refers to: St6galnac4
refers to: 1418075_at
t statistic: -5.48415638302578

1424050_s_at
type: EFO_0005072
part of: A-AFFY-23

Kit
type: EnsemblDatabaseReference

Acaa2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01407085703378
p value: 0.0350448481165821
refers to: Acaa2
refers to: 1428146_s_at
t statistic: 3.53335516786975

Lrg1
type: EnsemblDatabaseReference

Cryab
type: EnsemblDatabaseReference

Cyp2f2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.19239815496083
p value: 0.0193420241024043
refers to: Cyp2f2
refers to: 1448792_a_at
t statistic: 4.13136848135489

Ckmt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.46105216757261
p value: 0.0033155075102047
refers to: Ckmt1
refers to: 1417089_a_at
t statistic: 6.02992264135127

1449212_at
type: EFO_0005072
part of: A-AFFY-23

Bid DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06708845920665
p value: 0.0145394954861109
refers to: 1417045_at
refers to: Bid
t statistic: -4.42599269872999

(Assay) GSM356511
type: Assay
has participant: A-AFFY-23

Fam174b DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22336166430666
p value: 0.0190325197862201
refers to: Fam174b
refers to: 1434273_at
t statistic: -4.15179572420938

Col9a1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.64560813161596
p value: 6.13621353017918E-4
refers to: Col9a1
refers to: 1421381_a_at
t statistic: -8.46221419875678

1425458_a_at
type: EFO_0005072
part of: A-AFFY-23

Cyp2f2
type: EnsemblDatabaseReference

Nfib
type: EnsemblDatabaseReference

Add3
type: EnsemblDatabaseReference

1424737_at
type: EFO_0005072
part of: A-AFFY-23

1424127_at
type: EFO_0005072
part of: A-AFFY-23

Eya2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02755641814583
p value: 0.033998012476743
refers to: Eya2
refers to: 1424127_at
t statistic: 3.5693412324369

Selenbp1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.07935530045757
p value: 0.00921564970974987
refers to: Selenbp1
refers to: 1450699_at
t statistic: 4.91015699177328

Bex1
type: EnsemblDatabaseReference

Pigr
type: EnsemblDatabaseReference

Grb10 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.10824825943932
p value: 0.0166299031686836
refers to: 1425458_a_at
refers to: Grb10
t statistic: 4.29045532425054

Nfib DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09185472951025
p value: 0.00378414514026317
refers to: Nfib
refers to: 1438245_at
t statistic: -5.82603511078799

1453851_a_at
type: EFO_0005072
part of: A-AFFY-23

Chpt1
type: EnsemblDatabaseReference

E-GEOD-14226
type: microarray 1colour mrna differential
RO_0002162: Mus musculus
description: We previously identified a novel SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors, but is dispensable for normal development. Reconstitution experiments revealed that Hunk is sufficient to restore the metastatic potential of Hunk-deficient tumor cells, as well as defects in migration and invasion, and does so in a manner that requires its kinase activity. Consistent with a role for Hunk in the progression of human cancers, the human homologue of Hunk is overexpressed in aggressive subsets of carcinomas of the ovary, colon, and breast. In addition, a murine gene expression signature that distinguishes Hunk-wild type from Hunk-deficient mammary tumors predicts clinical outcome in women with breast cancer. Together, these findings establish a role for Hunk in metastasis and an in vivo function for this kinase. Hunk-deficient animals were crossed to mice harboring an MMTV-c-myc transgene (Leder et al., 1986). Hunk heterozygous, MMTV-c-myc mice were backcrossed to Hunk heterozygous animals. MMTV-c-myc female animals of each Hunk genotype were mated twice, then monitored twice weekly for mammary tumors. Mice possessing tumors with a maximum diameter of 20 mm were sacrificed and organs were examined at necropsy. Tumor nodules were identified by examination of organs through a Leica Wild MZ8 dissection microscope.
uses data from: http://identifiers.org/pubmed/19717424

1810011O10Rik
type: EnsemblDatabaseReference

Lrg1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.92684882770082
p value: 0.0443601317386155
refers to: 1417290_at
refers to: Lrg1
t statistic: 3.32747093980201

(Assay) GSM356505
type: Assay
has participant: A-AFFY-23

Nr4a1
type: EnsemblDatabaseReference

Slc28a3
type: EnsemblDatabaseReference

C3
type: EnsemblDatabaseReference

1451348_at
type: EFO_0005072
part of: A-AFFY-23

1450958_at
type: EFO_0005072
part of: A-AFFY-23

1448881_at
type: EFO_0005072
part of: A-AFFY-23

1448213_at
type: EFO_0005072
part of: A-AFFY-23

Tm4sf1
type: EnsemblDatabaseReference

Sgk1
type: EnsemblDatabaseReference

Ddit4 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.30245353545813
p value: 0.00378414514026317
refers to: 1428306_at
refers to: Ddit4
t statistic: 5.82863587145156

1449885_at
type: EFO_0005072
part of: A-AFFY-23

Chn2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.54510879299796
p value: 0.00100619404063469
refers to: Chn2
refers to: 1428574_a_at
t statistic: -7.64567363652974

Shf DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.36396423863652
p value: 9.42720753697921E-4
refers to: 1436167_at
refers to: Shf
t statistic: -8.00986579173157

(Assay) GSM356513
type: Assay
has participant: A-AFFY-23

1452318_a_at
type: EFO_0005072
part of: A-AFFY-23

1428306_at
type: EFO_0005072
part of: A-AFFY-23

Ctbp2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23898416437937
p value: 0.00417630591296217
refers to: 1434705_at
refers to: Ctbp2
t statistic: -5.73947548196784

Serpine2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16423811557383
p value: 0.0460223752126018
refers to: 1416666_at
refers to: Serpine2
t statistic: -3.29560304123608

1448415_a_at
type: EFO_0005072
part of: A-AFFY-23

2610018G03Rik DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.04100594784968
p value: 0.00268050978576594
refers to: 2610018G03Rik
refers to: 1419033_at
t statistic: -6.23158748134935

1417565_at
type: EFO_0005072
part of: A-AFFY-23

Fam3c DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05317099864223
p value: 0.0283788017757694
refers to: 1417953_at
refers to: Fam3c
t statistic: -3.75671275319513

Spry2
type: EnsemblDatabaseReference

1418569_at
type: EFO_0005072
part of: A-AFFY-23

1450839_at
type: EFO_0005072
part of: A-AFFY-23

Socs2
type: EnsemblDatabaseReference

(Assay) GSM356508
type: Assay
has participant: A-AFFY-23

Tmem47
type: EnsemblDatabaseReference

Cryab UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.34567878709662
p value: 0.00868650367524412
refers to: Cryab
refers to: 1416455_a_at
t statistic: 5.01381066759401

1418318_at
type: EFO_0005072
part of: A-AFFY-23

Deptor
type: EnsemblDatabaseReference

1426574_a_at
type: EFO_0005072
part of: A-AFFY-23

1436167_at
type: EFO_0005072
part of: A-AFFY-23

Ltf UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.40471276841781
p value: 0.0115525762428192
refers to: 1450009_at
refers to: Ltf
t statistic: 4.68272787343608

Deptor DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.9783987257646
p value: 0.0033155075102047
refers to: Deptor
refers to: 1451348_at
t statistic: -6.00218392931129

Pax6 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.05834156831927
p value: 0.00264091133143383
refers to: 1419271_at
refers to: Pax6
t statistic: 6.31977726361665

Slc6a15 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.21019703034844
p value: 0.0033155075102047
refers to: Slc6a15
refers to: 1426712_at
t statistic: -5.99870769801798

1419571_at
type: EFO_0005072
part of: A-AFFY-23

2610018G03Rik
type: EnsemblDatabaseReference

1433579_at
type: EFO_0005072
part of: A-AFFY-23

Nrep
type: EnsemblDatabaseReference

1448792_a_at
type: EFO_0005072
part of: A-AFFY-23

Acaa2
type: EnsemblDatabaseReference

Fam174b
type: EnsemblDatabaseReference

Ctbp2
type: EnsemblDatabaseReference

Plet1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.04261507894803
p value: 0.0117490089321073
refers to: 1423933_a_at
refers to: Plet1
t statistic: 4.65121580893237

Cpd DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.18038728904371
p value: 0.028280737422486
refers to: 1455009_at
refers to: Cpd
t statistic: -3.75958762477811

4931406C07Rik
type: EnsemblDatabaseReference

1460372_at
type: EFO_0005072
part of: A-AFFY-23

Anxa1
type: EnsemblDatabaseReference

Tceal8
type: EnsemblDatabaseReference

Bex2
type: EnsemblDatabaseReference

1426236_a_at
type: EFO_0005072
part of: A-AFFY-23

1418505_at
type: EFO_0005072
part of: A-AFFY-23

Spry2 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.31676694298364
p value: 1.52151519243792E-4
refers to: Spry2
refers to: 1436584_at
t statistic: -11.0151244053355

Pik3r1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.31506420418164
p value: 0.0352716551700899
refers to: Pik3r1
refers to: 1425514_at
t statistic: 3.52673693106673

Evl
type: EnsemblDatabaseReference

Selenbp1
type: EnsemblDatabaseReference

Grb10
type: EnsemblDatabaseReference

Tm4sf1
type: EnsemblDatabaseReference

Elf5
type: EnsemblDatabaseReference

1425514_at
type: EFO_0005072
part of: A-AFFY-23

Tmem30b
type: EnsemblDatabaseReference

St6galnac4
type: EnsemblDatabaseReference

Kcnn4
type: EnsemblDatabaseReference

Ckmt1
type: EnsemblDatabaseReference

1455009_at
type: EFO_0005072
part of: A-AFFY-23

1452514_a_at
type: EFO_0005072
part of: A-AFFY-23

Krt79 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.66848902422185
p value: 0.0174928040406667
refers to: Krt79
refers to: 1427352_at
t statistic: 4.23449167908625

Tfcp2l1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.80826348658897
p value: 0.0297329862202064
refers to: Tfcp2l1
refers to: 1418091_at
t statistic: 3.70456329688491

Hp UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 3.0253528396809
p value: 1.62266161760992E-4
refers to: 1448881_at
refers to: Hp
t statistic: 9.95753971525852

1426146_a_at
type: EFO_0005072
part of: A-AFFY-23

1416666_at
type: EFO_0005072
part of: A-AFFY-23

Serpine2
type: EnsemblDatabaseReference

Hspa1b UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.28384117153587
p value: 0.00521044027770734
refers to: Hspa1b
refers to: 1452318_a_at
t statistic: 5.48417037264114

Pax6
type: EnsemblDatabaseReference

Elf5 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.39068975832348
p value: 0.013053701183097
refers to: Elf5
refers to: 1419555_at
t statistic: 4.52198550248667

Bex1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.69704607187109
p value: 0.0040714369020007
refers to: Bex1
refers to: 1448595_a_at
t statistic: -5.7651805571554

1455901_at
type: EFO_0005072
part of: A-AFFY-23

Hp
type: EnsemblDatabaseReference

Pik3r1
type: EnsemblDatabaseReference

(Assay) GSM356512
type: Assay
has participant: A-AFFY-23

Col9a1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -2.70185114350614
p value: 0.00126599321102382
refers to: Col9a1
refers to: 1428571_at
t statistic: -7.15506296884591

Bdh1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.55750918398688
p value: 0.0226226646062332
refers to: 1452257_at
refers to: Bdh1
t statistic: 3.98652005405747

Glul
type: EnsemblDatabaseReference

Rbp7 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12495726009992
p value: 0.0033155075102047
refers to: Rbp7
refers to: 1449461_at
t statistic: -5.99862570702938

Chn2
type: EnsemblDatabaseReference

1417156_at
type: EFO_0005072
part of: A-AFFY-23

Emid1
type: EnsemblDatabaseReference

Col9a1
type: EnsemblDatabaseReference

Etv5
type: EnsemblDatabaseReference

1434273_at
type: EFO_0005072
part of: A-AFFY-23

Thrsp
type: EnsemblDatabaseReference

Nrep
type: EnsemblDatabaseReference

(Assay) GSM356506
type: Assay
has participant: A-AFFY-23

Chpt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.22470161821977
p value: 0.00162002647765672
refers to: 1435446_a_at
refers to: Chpt1
t statistic: 6.89943124972561

Nupr1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.09744976844476
p value: 0.0128641043889532
refers to: Nupr1
refers to: 1419665_a_at
t statistic: 4.54639199645882

Rnf128
type: EnsemblDatabaseReference

(Assay) GSM356515
type: Assay
has participant: A-AFFY-23

1418507_s_at
type: EFO_0005072
part of: A-AFFY-23

Prom1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.41832947665785
p value: 0.0145123905835822
refers to: Prom1
refers to: 1419700_a_at
t statistic: -4.43361700032088

Aldoc
type: EnsemblDatabaseReference

Cpd
type: EnsemblDatabaseReference

Nupr1
type: EnsemblDatabaseReference

Bex2
type: EnsemblDatabaseReference

Fgfr1
type: EnsemblDatabaseReference

Cytip UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13387838414042
p value: 0.0046412797746707
refers to: Cytip
refers to: 1451206_s_at
t statistic: 5.62654957311594

1451461_a_at
type: EFO_0005072
part of: A-AFFY-23

Cbr2 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.7613752072608
p value: 4.84259738677606E-6
refers to: 1418509_at
refers to: Cbr2
t statistic: 15.6809292649068

Dcxr
type: EnsemblDatabaseReference

Pros1
type: EnsemblDatabaseReference

Nudt4 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3424686462707
p value: 0.00456667620476251
refers to: Nudt4
refers to: 1418505_at
t statistic: -5.66327510052981

(Assay) GSM356510
type: Assay
has participant: A-AFFY-23

1450082_s_at
type: EFO_0005072
part of: A-AFFY-23

Lrg1
type: EnsemblDatabaseReference

1451415_at
type: EFO_0005072
part of: A-AFFY-23

1434369_a_at
type: EFO_0005072
part of: A-AFFY-23

Ckmt1
type: EnsemblDatabaseReference

(Assay) GSM356507
type: Assay
has participant: A-AFFY-23

Cryab
type: EnsemblDatabaseReference

1417953_at
type: EFO_0005072
part of: A-AFFY-23

Bid
type: EnsemblDatabaseReference

Rhpn2
type: EnsemblDatabaseReference

Ltf
type: EnsemblDatabaseReference

1423104_at
type: EFO_0005072
part of: A-AFFY-23

Akap12
type: EnsemblDatabaseReference

Cytip
type: EnsemblDatabaseReference

1449581_at
type: EFO_0005072
part of: A-AFFY-23

(Assay) GSM356514
type: Assay
has participant: A-AFFY-23

Shf
type: EnsemblDatabaseReference

1432418_a_at
type: EFO_0005072
part of: A-AFFY-23

G0s2
type: EnsemblDatabaseReference

Cyp2f2
type: EnsemblDatabaseReference

Irs1
type: EnsemblDatabaseReference

Nfib
type: EnsemblDatabaseReference

Add3
type: EnsemblDatabaseReference

Pigr UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.50538128150566
p value: 0.0466013492935699
refers to: Pigr
refers to: 1455490_at
t statistic: 3.28561947595709

Fblim1
type: EnsemblDatabaseReference

Chpt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.96197842467136
p value: 0.00126599321102382
refers to: Chpt1
refers to: 1455901_at
t statistic: 7.20756004911773

Ccl28
type: EnsemblDatabaseReference

Pik3r1
type: EnsemblDatabaseReference

Dusp6
type: EnsemblDatabaseReference

Etv5 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.93280576801972
p value: 3.4209523426201E-4
refers to: Etv5
refers to: 1450082_s_at
t statistic: -9.12756600960285

Hspa1b UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.59415132358286
p value: 0.00432857952560993
refers to: 1427126_at
refers to: Hspa1b
t statistic: 5.70731072201285

Chpt1 UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.92869347830135
p value: 1.62266161760992E-4
refers to: Chpt1
refers to: 1435870_at
t statistic: 9.99283736730123

1421038_a_at
type: EFO_0005072
part of: A-AFFY-23

Chpt1
type: EnsemblDatabaseReference

Tceal8 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20668347256019
p value: 0.00542353384116837
refers to: 1418171_at
refers to: Tceal8
t statistic: -5.43627303334552

1427126_at
type: EFO_0005072
part of: A-AFFY-23

Nr4a1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24688465586192
p value: 0.0241000997527104
refers to: Nr4a1
refers to: 1416505_at
t statistic: -3.91016058994733

Bdh1
type: EnsemblDatabaseReference

Pigr UP in 'Hunk knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.50708528059241
p value: 0.0425964652409164
refers to: Pigr
refers to: 1450060_at
t statistic: 3.36829230253089

1418018_at
type: EFO_0005072
part of: A-AFFY-23

Etv5
type: EnsemblDatabaseReference

Duoxa1
type: EnsemblDatabaseReference

Plet1
type: EnsemblDatabaseReference

Slc28a3
type: EnsemblDatabaseReference

C3
type: EnsemblDatabaseReference

Tfcp2l1
type: EnsemblDatabaseReference

Tm4sf1 DOWN in 'Hunk knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.44258175673645
p value: 0.0261617312338409
refers to: 1450958_at
refers to: Tm4sf1
t statistic: -3.83218002056494