Cp
type: EnsemblDatabaseReference

Igfbp4 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00164560378152
p value: 5.57388253356385E-4
refers to: 1423757_x_at
refers to: Igfbp4
t statistic: -9.80632300901445

Abtb2
type: EnsemblDatabaseReference

Edil3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20320638363848
p value: 0.0117057403630552
refers to: Edil3
refers to: 1433474_at
t statistic: -5.15651476370427

1437339_s_at
type: EFO_0005072
part of: A-AFFY-45

SERPINA1
type: EnsemblDatabaseReference

Igfbp4 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.31839003872112
p value: 5.57388253356385E-4
refers to: Igfbp4
refers to: 1423756_s_at
t statistic: -9.74217649937424

Olr1
type: EnsemblDatabaseReference

1418679_at
type: EFO_0005072
part of: A-AFFY-45

Hspa1a DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2619614694423
p value: 0.00511461741314366
refers to: Hspa1a
refers to: 1452388_at
t statistic: -6.44582911175155

Gdf10
type: EnsemblDatabaseReference

(Assay) GSM303297
type: Assay
has participant: A-AFFY-44

1427127_x_at
type: EFO_0005072
part of: A-AFFY-45

Brinp3
type: EnsemblDatabaseReference

1426968_a_at
type: EFO_0005072
part of: A-AFFY-45

Gzmf
type: EnsemblDatabaseReference

1416200_at
type: EFO_0005072
part of: A-AFFY-45

Epha3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.54445141618774
p value: 0.0162960806749553
refers to: Epha3
refers to: 1425575_at
t statistic: -4.69278202047161

Gzmf
type: EnsemblDatabaseReference

Gzmf DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22735253614327
p value: 5.57388253356385E-4
refers to: Gzmf
refers to: 1418679_at
t statistic: -9.75419285103547

Slc20a1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14569445850231
p value: 0.0175805747843968
refers to: 1438824_at
refers to: Slc20a1
t statistic: -4.57902463257396

1448147_at
type: EFO_0005072
part of: A-AFFY-45

Gdf10 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.38992821872757
p value: 0.00627216819481686
refers to: Gdf10
refers to: 1424007_at
t statistic: -6.13998962986414

1452114_s_at
type: EFO_0005072
part of: A-AFFY-45

St8sia2
type: EnsemblDatabaseReference

Igfbp5
type: EnsemblDatabaseReference

Il11
type: EnsemblDatabaseReference

Gzmg
type: EnsemblDatabaseReference

Gli2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19188668741285
p value: 0.00167689842026713
refers to: Gli2
refers to: 1459211_at
t statistic: -8.07210934489701

Trim12c UP in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13266442651901
p value: 0.0279106759459519
refers to: 1443858_at
refers to: Trim12c
t statistic: 3.95474746482227

Wif1
type: EnsemblDatabaseReference

1434993_at
type: EFO_0005072
part of: A-AFFY-45

1422253_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM303310
type: Assay
has participant: A-AFFY-45

Edil3
type: EnsemblDatabaseReference

1433474_at
type: EFO_0005072
part of: A-AFFY-45

Wif1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.63559278225554
p value: 0.0166367717492344
refers to: Wif1
refers to: 1425425_a_at
t statistic: -4.66984250805429

Cygb DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1320009035431
p value: 0.00239459054528401
refers to: 1423630_at
refers to: Cygb
t statistic: -7.440572382917

Epha3
type: EnsemblDatabaseReference

Gzmc
type: EnsemblDatabaseReference

Gli2
type: EnsemblDatabaseReference

Lrig3
type: EnsemblDatabaseReference

Igfbp4
type: EnsemblDatabaseReference

Ptger3
type: EnsemblDatabaseReference

Ahr DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1205924146489
p value: 0.0136274735247233
refers to: Ahr
refers to: 1422631_at
t statistic: -4.95394721510988

Pappa
type: EnsemblDatabaseReference

Gzmg DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15386182932121
p value: 0.00541531688217478
refers to: Gzmg
refers to: 1422867_at
t statistic: -6.3222482515055

1438160_x_at
type: EFO_0005072
part of: A-AFFY-45

1421992_a_at
type: EFO_0005072
part of: A-AFFY-45

Pappa
type: EnsemblDatabaseReference

Trim12c
type: EnsemblDatabaseReference

Trim12c
type: EnsemblDatabaseReference

SERPINA1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.79396356312236
p value: 0.0289639918939263
refers to: SERPINA1
refers to: 211429_s_at
t statistic: -5.31536363759976

Hspa1b DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18486395883023
p value: 0.00189648664245013
refers to: Hspa1b
refers to: 1427126_at
t statistic: -7.80615088723383

SERPINA1
type: EnsemblDatabaseReference

Cygb
type: EnsemblDatabaseReference

Penk DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.59046898834132
p value: 6.11986218436833E-4
refers to: Penk
refers to: 1427038_at
t statistic: -9.50030839529976

1434667_at
type: EFO_0005072
part of: A-AFFY-45

Dkk2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15532793790847
p value: 0.022556514992854
refers to: Dkk2
refers to: 1420512_at
t statistic: -4.25940955020888

202833_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM303300
type: Assay
has participant: A-AFFY-44

Hspa1a
type: EnsemblDatabaseReference

204932_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) GSM303305
type: Assay
has participant: A-AFFY-45

Rdh10
type: EnsemblDatabaseReference

Lepr DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.297013639493
p value: 0.0382046985284034
refers to: Lepr
refers to: 1456156_at
t statistic: -3.56977367862262

Penk
type: EnsemblDatabaseReference

Il11 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05170705276141
p value: 0.00754680274228655
refers to: Il11
refers to: 1449982_at
t statistic: -5.83062439709712

(Assay) GSM303304
type: Assay
has participant: A-AFFY-45

(Assay) GSM303296
type: Assay
has participant: A-AFFY-44

Dkk2
type: EnsemblDatabaseReference

211429_s_at
type: EFO_0005072
part of: A-AFFY-44

TNFRSF11B
type: EnsemblDatabaseReference

Dkk2
type: EnsemblDatabaseReference

Mpzl2
type: EnsemblDatabaseReference

1449982_at
type: EFO_0005072
part of: A-AFFY-45

Gzmc DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.074998414102
p value: 0.0152924433504917
refers to: 1421256_at
refers to: Gzmc
t statistic: -4.78366648593089

1449038_at
type: EFO_0005072
part of: A-AFFY-45

1416236_a_at
type: EFO_0005072
part of: A-AFFY-45

1452388_at
type: EFO_0005072
part of: A-AFFY-45

1443858_at
type: EFO_0005072
part of: A-AFFY-45

Tnfrsf19
type: EnsemblDatabaseReference

Lepr
type: EnsemblDatabaseReference

Reg1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.46383572666923
p value: 1.14798848878295E-4
refers to: Reg1
refers to: 1415905_at
t statistic: -14.4638374000425

Aldh1a3
type: EnsemblDatabaseReference

1427053_at
type: EFO_0005072
part of: A-AFFY-45

1432591_at
type: EFO_0005072
part of: A-AFFY-45

Aldh1a3
type: EnsemblDatabaseReference

Lepr
type: EnsemblDatabaseReference

Frzb
type: EnsemblDatabaseReference

Abi3bp
type: EnsemblDatabaseReference

A-AFFY-44
type: EFO_0000269

Col8a2
type: EnsemblDatabaseReference

Ahr
type: EnsemblDatabaseReference

TNFRSF11B DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04345398877376
p value: 0.042721079861572
refers to: TNFRSF11B
refers to: 204932_at
t statistic: -4.06474935999658

Slco4a1
type: EnsemblDatabaseReference

Slco4a1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24242884786089
p value: 5.57388253356385E-4
refers to: Slco4a1
refers to: 1438160_x_at
t statistic: -9.7892539067356

Col8a2
type: EnsemblDatabaseReference

1448568_a_at
type: EFO_0005072
part of: A-AFFY-45

Galr2
type: EnsemblDatabaseReference

Hspa1b DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19905182441397
p value: 0.00176909171070114
refers to: Hspa1b
refers to: 1452318_a_at
t statistic: -7.92618845407136

Slc20a1
type: EnsemblDatabaseReference

1421256_at
type: EFO_0005072
part of: A-AFFY-45

1422942_at
type: EFO_0005072
part of: A-AFFY-45

Bpgm
type: EnsemblDatabaseReference

Hspa1b DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.26794830284377
p value: 0.00167689842026713
refers to: 1427127_x_at
refers to: Hspa1b
t statistic: -8.05465197782784

Abtb2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.190599543734
p value: 0.00532304015074583
refers to: 1433453_a_at
refers to: Abtb2
t statistic: -6.37052995452595

Il33
type: EnsemblDatabaseReference

1433453_a_at
type: EFO_0005072
part of: A-AFFY-45

Hspa1b
type: EnsemblDatabaseReference

Abi3bp DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13641373434822
p value: 5.57388253356385E-4
refers to: 1427054_s_at
refers to: Abi3bp
t statistic: -9.6837304916174

Pcsk5 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.63517705336711
p value: 1.23736011301202E-4
refers to: 1451406_a_at
refers to: Pcsk5
t statistic: -12.727284766647

Sertad4 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22722394727368
p value: 1.23736011301202E-4
refers to: 1454877_at
refers to: Sertad4
t statistic: -12.6074143594737

1420512_at
type: EFO_0005072
part of: A-AFFY-45

Mcpt1
type: EnsemblDatabaseReference

1423757_x_at
type: EFO_0005072
part of: A-AFFY-45

1460632_at
type: EFO_0005072
part of: A-AFFY-45

Homo sapiens
type: OBI_0100026

1422867_at
type: EFO_0005072
part of: A-AFFY-45

Gdf10
type: EnsemblDatabaseReference

1456156_at
type: EFO_0005072
part of: A-AFFY-45

Analysis of '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]'
type: MicroarrayDifferentialExpressionAnalysis

(Assay) GSM303302
type: Assay
has participant: A-AFFY-44

Frzb DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2414834084211
p value: 0.00880528116485061
refers to: Frzb
refers to: 1448424_at
t statistic: -5.57461856350097

Brinp3
type: EnsemblDatabaseReference

(Assay) GSM303298
type: Assay
has participant: A-AFFY-44

1454877_at
type: EFO_0005072
part of: A-AFFY-45

(Factor value) COMPOUND/vehicle
type: EFO_0000732
property type: COMPOUND
property value: vehicle

1425575_at
type: EFO_0005072
part of: A-AFFY-45

Pcsk5
type: EnsemblDatabaseReference

Cp DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0114800521756
p value: 0.00946739493627744
refers to: Cp
refers to: 1448734_at
t statistic: -5.46722550835028

Col10a1
type: EnsemblDatabaseReference

Cp
type: EnsemblDatabaseReference

1448734_at
type: EFO_0005072
part of: A-AFFY-45

1422352_at
type: EFO_0005072
part of: A-AFFY-45

Pappa UP in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02254494098381
p value: 0.00812910154451029
refers to: Pappa
refers to: 1432591_at
t statistic: 5.71580357562953

Mcpt1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24679709663441
p value: 0.0116749566636249
refers to: Mcpt1
refers to: 1422352_at
t statistic: -5.16265096169646

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

1452318_a_at
type: EFO_0005072
part of: A-AFFY-45

St8sia2
type: EnsemblDatabaseReference

Abtb2
type: EnsemblDatabaseReference

Igfbp5
type: EnsemblDatabaseReference

Pcsk5 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.41012964937373
p value: 7.06285857255965E-4
refers to: Pcsk5
refers to: 1437339_s_at
t statistic: -9.28486643261577

Col8a2 UP in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: IncreasedDifferentialExpressionRatio
fold change: 1.00139430344026
p value: 0.0174312375897818
refers to: Col8a2
refers to: 1434667_at
t statistic: 4.59114682025599

Olr1
type: EnsemblDatabaseReference

Igfbp4 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.28381707186357
p value: 8.51030650349962E-4
refers to: 1421992_a_at
refers to: Igfbp4
t statistic: -8.89625119556575

1422631_at
type: EFO_0005072
part of: A-AFFY-45

1416658_at
type: EFO_0005072
part of: A-AFFY-45

Edil3
type: EnsemblDatabaseReference

(Assay) GSM303308
type: Assay
has participant: A-AFFY-45

1438824_at
type: EFO_0005072
part of: A-AFFY-45

Analysis of '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: MicroarrayDifferentialExpressionAnalysis

1415905_at
type: EFO_0005072
part of: A-AFFY-45

Gli2
type: EnsemblDatabaseReference

1420377_at
type: EFO_0005072
part of: A-AFFY-45

Igfbp4
type: EnsemblDatabaseReference

(Assay) GSM303307
type: Assay
has participant: A-AFFY-45

1448789_at
type: EFO_0005072
part of: A-AFFY-45

1427054_s_at
type: EFO_0005072
part of: A-AFFY-45

1425425_a_at
type: EFO_0005072
part of: A-AFFY-45

Aldh1a3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.09696757208624
p value: 0.0109480054419629
refers to: Aldh1a3
refers to: 1448789_at
t statistic: -5.26410322863293

(Assay) GSM303299
type: Assay
has participant: A-AFFY-44

Sertad4
type: EnsemblDatabaseReference

Il11
type: EnsemblDatabaseReference

1423630_at
type: EFO_0005072
part of: A-AFFY-45

Gzmg
type: EnsemblDatabaseReference

(Assay) GSM303309
type: Assay
has participant: A-AFFY-45

(Sample) disease/pancreatic carcinoma
type: EFO_0002618
property type: disease
property value: pancreatic carcinoma

Sertad4
type: EnsemblDatabaseReference

Lrig3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05825726961038
p value: 0.00595730758358883
refers to: Lrig3
refers to: 1430554_at
t statistic: -6.2019180764661

1451406_a_at
type: EFO_0005072
part of: A-AFFY-45

1430554_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM303301
type: Assay
has participant: A-AFFY-44

1423756_s_at
type: EFO_0005072
part of: A-AFFY-45

Galr2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.21219319314464
p value: 0.00558982819794814
refers to: 1422942_at
refers to: Galr2
t statistic: -6.28057304643438

Rdh10
type: EnsemblDatabaseReference

Brinp3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03122813963463
p value: 0.0397820915378739
refers to: Brinp3
refers to: 1434993_at
t statistic: -3.50854780185079

Penk
type: EnsemblDatabaseReference

Wif1
type: EnsemblDatabaseReference

(Assay) GSM303303
type: Assay
has participant: A-AFFY-45

Mpzl2
type: EnsemblDatabaseReference

A-AFFY-45
type: EFO_0000269

1455426_at
type: EFO_0005072
part of: A-AFFY-45

Gzmc
type: EnsemblDatabaseReference

Epha3
type: EnsemblDatabaseReference

Lrig3
type: EnsemblDatabaseReference

Ptger3
type: EnsemblDatabaseReference

Col10a1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.40094118197879
p value: 7.76275594923132E-4
refers to: Col10a1
refers to: 1422253_at
t statistic: -9.03523551816667

Bpgm DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08166287154305
p value: 0.00214651236733701
refers to: Bpgm
refers to: 1415864_at
t statistic: -7.55967315966284

1427038_at
type: EFO_0005072
part of: A-AFFY-45

Tnfrsf19
type: EnsemblDatabaseReference

Mpzl2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.12493940900618
p value: 4.15318908672905E-4
refers to: Mpzl2
refers to: 1448265_x_at
t statistic: -10.5712426894282

1459211_at
type: EFO_0005072
part of: A-AFFY-45

Slc20a1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00156942920979
p value: 0.0205520589887111
refers to: Slc20a1
refers to: 1448568_a_at
t statistic: -4.35534930879498

Igfbp5 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -4.77521734858274
p value: 1.14798848878295E-4
refers to: Igfbp5
refers to: 1452114_s_at
t statistic: -14.3752606573207

Cygb
type: EnsemblDatabaseReference

Abi3bp
type: EnsemblDatabaseReference

1427126_at
type: EFO_0005072
part of: A-AFFY-45

Ahr
type: EnsemblDatabaseReference

Tnfrsf19 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.63261652086412
p value: 5.57388253356385E-4
refers to: Tnfrsf19
refers to: 1448147_at
t statistic: -9.92800699072513

Ptger3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.07717976743417
p value: 1.23736011301202E-4
refers to: 1450344_a_at
refers to: Ptger3
t statistic: -13.7032999475675

E-GEOD-11981
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: Four vehicle-treated and four HhAntag-treated pancreatic xenograft tumors were profiled for gene expression changes using Affymetrix U133 Plus 2.0 and Affymetrix Mouse Genome 430 2.0 arrays. Keywords: comparative gene expression, hedgehog, hh A primary human pancreatic tumor xenograft (1051178-A) was established by direct implantation of surgical material into female CD1 nu/nu mice of 6-8 weeks of age. Tumors were serially passaged into larger cohorts of mice for efficacy testing and subsequently distributed into tumor volume-matched cohorts upon tumors reaching between 200 to 350 mm3. HhAntag was resuspended in 0.5% methyl-cellulose, 0.2% Tween-80 (MCT) and administered orally twice daily at 75 mg/kg from a 10 mg/ml suspension. MCT alone served as vehicle control. Tumor xenografts (4/group) were excised following 21 days of dosing and RNA was extracted. Preparation of complementary RNA, Human Genome U133 Plus 2.0 array and Mouse Genome 430 2.0 array hybridizations, and subsequent data analysis were carried out using Affymetrix protocols, with signal intensities being determined by the MAS5.0 algorithm.
uses data from: http://identifiers.org/pubmed/18754008

Slco4a1
type: EnsemblDatabaseReference

Reg1
type: EnsemblDatabaseReference

Galr2
type: EnsemblDatabaseReference

Hspa1a
type: EnsemblDatabaseReference

Rdh10 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.67789216574168
p value: 5.57388253356385E-4
refers to: 1460632_at
refers to: Rdh10
t statistic: -9.71214330347678

Reg1
type: EnsemblDatabaseReference

Slc20a1
type: EnsemblDatabaseReference

Bpgm
type: EnsemblDatabaseReference

(Sample) xenograft/female CD1 nu/nu mice
type: EFO_0000001
property type: xenograft
property value: female CD1 nu/nu mice

Hsd11b1
type: EnsemblDatabaseReference

1448424_at
type: EFO_0005072
part of: A-AFFY-45

(Assay) GSM303306
type: Assay
has participant: A-AFFY-45

(Factor value) COMPOUND/HhAntag 75
type: EFO_0000001
property type: COMPOUND
property value: HhAntag 75

Il33
type: EnsemblDatabaseReference

Hsd11b1
type: EnsemblDatabaseReference

Hspa1b
type: EnsemblDatabaseReference

St8sia2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06315869213176
p value: 9.18379690169776E-4
refers to: St8sia2
refers to: 1420377_at
t statistic: -8.73479312911408

Epha3 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.53929920828389
p value: 0.0171169641709122
refers to: Epha3
refers to: 1455426_at
t statistic: -4.62206154492029

1448265_x_at
type: EFO_0005072
part of: A-AFFY-45

Rdh10 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.84041681087104
p value: 1.23736011301202E-4
refers to: 1426968_a_at
refers to: Rdh10
t statistic: -12.9748996463531

Mcpt1
type: EnsemblDatabaseReference

1419534_at
type: EFO_0005072
part of: A-AFFY-45

Olr1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05461971769038
p value: 0.0201706106106645
refers to: 1419534_at
refers to: Olr1
t statistic: -4.37734318623902

(Assay) GSM303295
type: Assay
has participant: A-AFFY-44

1450344_a_at
type: EFO_0005072
part of: A-AFFY-45

SERPINA1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.89527994030442
p value: 0.0304788536592863
refers to: SERPINA1
refers to: 202833_s_at
t statistic: -5.19470654733173

1424007_at
type: EFO_0005072
part of: A-AFFY-45

Abi3bp DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16055734896277
p value: 7.06285857255965E-4
refers to: Abi3bp
refers to: 1427053_at
t statistic: -9.27869019242199

1415864_at
type: EFO_0005072
part of: A-AFFY-45

Frzb
type: EnsemblDatabaseReference

Il33 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.62325062819798
p value: 0.0141967033194349
refers to: Il33
refers to: 1416200_at
t statistic: -4.90651462562161

Mpzl2 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -2.0867113706264
p value: 1.23736011301202E-4
refers to: 1416236_a_at
refers to: Mpzl2
t statistic: -12.9171268962416

Hsd11b1 DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.49277798359604
p value: 5.57388253356385E-4
refers to: 1449038_at
refers to: Hsd11b1
t statistic: -9.76015398509755

Frzb DOWN in '75 milligram per kilogram HhAntag' vs 'vehicle' on 'Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06608164628546
p value: 0.015210956481371
refers to: Frzb
refers to: 1416658_at
t statistic: -4.79619701327422

TNFRSF11B
type: EnsemblDatabaseReference

Pcsk5
type: EnsemblDatabaseReference

Col10a1
type: EnsemblDatabaseReference