223748_at
type: EFO_0005072
part of: A-AFFY-44

DAB2
type: EnsemblDatabaseReference

HRG DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.60870323333333
p value: 0.012867228965771
refers to: 206226_at
refers to: HRG
t statistic: -4.77608681662889

RP11-295M3.4
type: EnsemblDatabaseReference

TXNIP UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0352319
p value: 0.0119209668692952
refers to: TXNIP
refers to: 201009_s_at
t statistic: 5.7397932571558

DYRK3
type: EnsemblDatabaseReference

PRRG4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4749856
p value: 0.0220769120617249
refers to: PRRG4
refers to: 238513_at
t statistic: -4.00014808385617

209101_at
type: EFO_0005072
part of: A-AFFY-44

DCLRE1B
type: EnsemblDatabaseReference

EHF DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0414776
p value: 0.0158272509569218
refers to: EHF
refers to: 225645_at
t statistic: -4.46591892829429

HPGD DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.33983103333333
p value: 0.0230493773027988
refers to: HPGD
refers to: 203914_x_at
t statistic: -3.92854432477767

HSPB8
type: EnsemblDatabaseReference

213652_at
type: EFO_0005072
part of: A-AFFY-44

SLC4A3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0825564
p value: 0.0076224917759682
refers to: SLC4A3
refers to: 205918_at
t statistic: -5.71830014921937

ITIH5
type: EnsemblDatabaseReference

ARHGAP42
type: EnsemblDatabaseReference

ELF5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.01028763333333
p value: 0.0148037938835517
refers to: ELF5
refers to: 220625_s_at
t statistic: -4.69208240754122

PAPPA
type: EnsemblDatabaseReference

GULP1
type: EnsemblDatabaseReference

ATP8B4 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1042619
p value: 0.0257214239760642
refers to: ATP8B4
refers to: 220416_at
t statistic: -3.8718306069295

SOX5
type: EnsemblDatabaseReference

RAMP1
type: EnsemblDatabaseReference

209875_s_at
type: EFO_0005072
part of: A-AFFY-44

MCHR1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09876733333333
p value: 0.00654471875877381
refers to: 230498_at
refers to: MCHR1
t statistic: -6.10476506988547

OSBPL1A
type: EnsemblDatabaseReference

FGA UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.37675433333333
p value: 0.00686259184598237
refers to: FGA
refers to: 205649_s_at
t statistic: 9.0790858992428

CYP3A5
type: EnsemblDatabaseReference

LCP1
type: EnsemblDatabaseReference

IL11 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0032857
p value: 0.00341229770646885
refers to: IL11
refers to: 206924_at
t statistic: 7.833149684632

213106_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) HepG2_Tmprss6_rep3
type: Assay
has participant: A-AFFY-44

RASSF8 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0692243
p value: 0.0361555085032198
refers to: RASSF8
refers to: 225946_at
t statistic: -3.33020909573891

SPATA16 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.53341403333333
p value: 0.0171701394983519
refers to: SPATA16
refers to: 223876_at
t statistic: -4.34990312488754

CDR2L
type: EnsemblDatabaseReference

(Assay) HepG2_mutant Tmprss6_rep2
type: Assay
identifier: HepG2_mutant Tmprss6_rep2
has participant: A-AFFY-44

C7
type: EnsemblDatabaseReference

SOX4
type: EnsemblDatabaseReference

Analysis of 'Tmprss6 wild type' vs 'empty vector'
type: MicroarrayDifferentialExpressionAnalysis

222889_at
type: EFO_0005072
part of: A-AFFY-44

RHOJ DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13612913333333
p value: 0.0127147595529134
refers to: RHOJ
refers to: 1555233_at
t statistic: -5.29094458501082

KRT23 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.131501
p value: 0.00345227250237603
refers to: KRT23
refers to: 218963_s_at
t statistic: 7.78091861957459

REPS2
type: EnsemblDatabaseReference

PCSK5
type: EnsemblDatabaseReference

(Factor value) GENOTYPE/Tmprss6 wild type
type: EFO_0000001
property type: GENOTYPE
property value: Tmprss6 wild type

MRPS6
type: EnsemblDatabaseReference

203373_at
type: EFO_0005072
part of: A-AFFY-44

207336_at
type: EFO_0005072
part of: A-AFFY-44

FGA
type: EnsemblDatabaseReference

NFIB DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08093203333333
p value: 0.0085824037614459
refers to: NFIB
refers to: 213032_at
t statistic: -5.4492339588513

203528_at
type: EFO_0005072
part of: A-AFFY-44

ITIH5
type: EnsemblDatabaseReference

ARHGAP42
type: EnsemblDatabaseReference

ZNF320
type: EnsemblDatabaseReference

SOX5
type: EnsemblDatabaseReference

(Assay) HepG2_Tmprss6_rep1
type: Assay
has participant: A-AFFY-44

209911_x_at
type: EFO_0005072
part of: A-AFFY-44

AKAP12 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.37835536666667
p value: 0.0109387824027848
refers to: AKAP12
refers to: 227529_s_at
t statistic: 6.42713905926353

SOCS2 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4319292
p value: 0.00648197879418359
refers to: SOCS2
refers to: 203372_s_at
t statistic: 6.15158383769094

ABCA5
type: EnsemblDatabaseReference

CYP3A7
type: EnsemblDatabaseReference

LCP1
type: EnsemblDatabaseReference

205918_at
type: EFO_0005072
part of: A-AFFY-44

RP11-295M3.4 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.17895376666667
p value: 0.0259851351612858
refers to: RP11-295M3.4
refers to: 222271_at
t statistic: -3.85558588385925

GPRC5A UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.195193
p value: 4.58911760358684E-4
refers to: 203108_at
refers to: GPRC5A
t statistic: 12.0193459090665

TNFSF14 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.22109486666667
p value: 0.026732064189236
refers to: TNFSF14
refers to: 207907_at
t statistic: 3.7096838568438

CAB39L
type: EnsemblDatabaseReference

242907_at
type: EFO_0005072
part of: A-AFFY-44

S1PR3
type: EnsemblDatabaseReference

HIST1H2BD DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.01995916666667
p value: 0.0119209668692952
refers to: 209911_x_at
refers to: HIST1H2BD
t statistic: -5.75743008443718

ARHGAP42 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.31760156666667
p value: 0.0195703298262851
refers to: ARHGAP42
refers to: 230047_at
t statistic: -4.19067506778256

SLC7A10 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3551043
p value: 0.0164119610206267
refers to: SLC7A10
refers to: 220868_s_at
t statistic: -4.50882563364221

228176_at
type: EFO_0005072
part of: A-AFFY-44

AQP3
type: EnsemblDatabaseReference

229299_at
type: EFO_0005072
part of: A-AFFY-44

213167_s_at
type: EFO_0005072
part of: A-AFFY-44

RASSF8
type: EnsemblDatabaseReference

MRPS6
type: EnsemblDatabaseReference

ATP8A1
type: EnsemblDatabaseReference

205500_at
type: EFO_0005072
part of: A-AFFY-44

PAPPA DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14580673333333
p value: 0.0220834884221817
refers to: 224942_at
refers to: PAPPA
t statistic: -4.04052585512786

IL11
type: EnsemblDatabaseReference

LRBA
type: EnsemblDatabaseReference

IGFBP1 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.87438
p value: 0.00420516123912835
refers to: IGFBP1
refers to: 205302_at
t statistic: 7.25196522590018

206924_at
type: EFO_0005072
part of: A-AFFY-44

CXCL8
type: EnsemblDatabaseReference

SOX4 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1126303
p value: 7.20360629638596E-5
refers to: SOX4
refers to: 201416_at
t statistic: 16.5229752745125

242005_at
type: EFO_0005072
part of: A-AFFY-44

HRG
type: EnsemblDatabaseReference

TNFSF14
type: EnsemblDatabaseReference

223657_at
type: EFO_0005072
part of: A-AFFY-44

KRTAP2-3
type: EnsemblDatabaseReference

PCSK5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.65833646666667
p value: 0.0127147595529134
refers to: PCSK5
refers to: 213652_at
t statistic: -5.22748374769729

LINC00973 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2267967
p value: 0.0119209668692952
refers to: LINC00973
refers to: 242005_at
t statistic: 5.6501812033262

DAB1
type: EnsemblDatabaseReference

ETNPPL
type: EnsemblDatabaseReference

LRBA DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.39891106666667
p value: 0.0140580976742758
refers to: LRBA
refers to: 214109_at
t statistic: -4.87471769554304

S1PR3
type: EnsemblDatabaseReference

FAM167B
type: EnsemblDatabaseReference

209289_at
type: EFO_0005072
part of: A-AFFY-44

CYP3A4
type: EnsemblDatabaseReference

CXCL8 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.78062606666667
p value: 4.015995893122E-6
refers to: 211506_s_at
refers to: CXCL8
t statistic: 24.531078747355

AQP3
type: EnsemblDatabaseReference

SLC4A11
type: EnsemblDatabaseReference

214235_at
type: EFO_0005072
part of: A-AFFY-44

RASSF8
type: EnsemblDatabaseReference

IGFBP1
type: EnsemblDatabaseReference

ANXA13 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.65994466666667
p value: 0.00686259184598237
refers to: 208323_s_at
refers to: ANXA13
t statistic: -8.58673797750579

ZNF320 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05310093333333
p value: 0.0058174339229464
refers to: ZNF320
refers to: 229614_at
t statistic: -6.37269981387175

LRBA DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.37264666666667
p value: 0.0124179254448253
refers to: LRBA
refers to: 214109_at
t statistic: -4.84888888348985

PRRG4 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00833
p value: 0.0378630594215105
refers to: PRRG4
refers to: 238513_at
t statistic: -3.44748188776415

SOX7
type: EnsemblDatabaseReference

SOX7 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5538284
p value: 0.0128425207028045
refers to: 228698_at
refers to: SOX7
t statistic: -5.12399861978757

ANKRD1
type: EnsemblDatabaseReference

UCP1
type: EnsemblDatabaseReference

207291_at
type: EFO_0005072
part of: A-AFFY-44

DCLRE1B DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.01801966666667
p value: 0.0101102885287894
refers to: 219490_s_at
refers to: DCLRE1B
t statistic: -5.17665139274433

206348_s_at
type: EFO_0005072
part of: A-AFFY-44

(Sample) genetic modification/transfection
type: EFO_0000726
property type: genetic modification
property value: transfection

(Assay) HepG2_mutant Tmprss6_rep1
type: Assay
identifier: HepG2_mutant Tmprss6_rep1
has participant: A-AFFY-44

MCHR1
type: EnsemblDatabaseReference

(Sample) genotype/empty vector
type: EFO_0000001
property type: genotype
property value: empty vector

MYLK4 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14873463333333
p value: 0.00346855630932223
refers to: 1556136_at
refers to: MYLK4
t statistic: -7.6994781229797

AKAP12 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.54390723333333
p value: 0.00159456566024244
refers to: AKAP12
refers to: 227530_at
t statistic: 9.58806247347095

TMEM27
type: EnsemblDatabaseReference

NADK2
type: EnsemblDatabaseReference

KRTAP2-3
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5116576
p value: 0.00448157085600792
refers to: RHOJ
refers to: 238906_s_at
t statistic: -7.06273316847245

228885_at
type: EFO_0005072
part of: A-AFFY-44

ETNPPL
type: EnsemblDatabaseReference

ANXA13
type: EnsemblDatabaseReference

LINC00973
type: EnsemblDatabaseReference

FAM167B DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7901055
p value: 0.0109387824027848
refers to: 223657_at
refers to: FAM167B
t statistic: -6.49832305072265

NR5A2
type: EnsemblDatabaseReference

(Sample) disease/liver carcinoma
type: EFO_0000182
property type: disease
property value: liver carcinoma

SOCS2 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.51235246666667
p value: 0.00130118098961283
refers to: SOCS2
refers to: 203373_at
t statistic: 10.0451647197719

SLC4A11
type: EnsemblDatabaseReference

MYZAP DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7740582
p value: 0.0106147930931836
refers to: MYZAP
refers to: 228568_at
t statistic: -6.56985498132059

TSC22D3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00981133333333
p value: 0.00940064469931604
refers to: TSC22D3
refers to: 207001_x_at
t statistic: -7.29902494312322

AKAP12
type: EnsemblDatabaseReference

FGA UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.07191616666667
p value: 0.00288117391250424
refers to: 205650_s_at
refers to: FGA
t statistic: 8.40470910208965

235489_at
type: EFO_0005072
part of: A-AFFY-44

201010_s_at
type: EFO_0005072
part of: A-AFFY-44

205999_x_at
type: EFO_0005072
part of: A-AFFY-44

SOCS2 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.178882
p value: 4.80197454849126E-4
refers to: 203373_at
refers to: SOCS2
t statistic: 14.0919660939731

SOWAHA
type: EnsemblDatabaseReference

230047_at
type: EFO_0005072
part of: A-AFFY-44

UCP1
type: EnsemblDatabaseReference

225946_at
type: EFO_0005072
part of: A-AFFY-44

1556136_at
type: EFO_0005072
part of: A-AFFY-44

PAPPA DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.536606
p value: 0.0109170827331933
refers to: PAPPA
refers to: 228128_x_at
t statistic: -5.03679011269633

CTGF
type: EnsemblDatabaseReference

CAPN8
type: EnsemblDatabaseReference

1558034_s_at
type: EFO_0005072
part of: A-AFFY-44

KRT23 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.051512
p value: 0.0109387824027848
refers to: KRT23
refers to: 218963_s_at
t statistic: 6.3018397694187

ANXA13 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3668455
p value: 0.00346855630932223
refers to: ANXA13
refers to: 208323_s_at
t statistic: -7.7283353625781

OSBPL1A DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1637719
p value: 0.0415683065949176
refers to: OSBPL1A
refers to: 209485_s_at
t statistic: -3.35473815211285

207907_at
type: EFO_0005072
part of: A-AFFY-44

CP
type: EnsemblDatabaseReference

REPS2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.44531513333333
p value: 0.0116793863845909
refers to: REPS2
refers to: 205645_at
t statistic: -5.98553079170333

ATP8A1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18938306666667
p value: 0.00988272742223153
refers to: 213106_at
refers to: ATP8A1
t statistic: -5.22697473939392

TXNIP
type: EnsemblDatabaseReference

TAGLN
type: EnsemblDatabaseReference

(Assay) HepG2_Vector_rep3
type: Assay
has participant: A-AFFY-44

AKAP12 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.699966
p value: 0.0014692078110688
refers to: AKAP12
refers to: 210517_s_at
t statistic: 9.76522628781439

ANG UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.44795346666667
p value: 0.0113258732369072
refers to: 205141_at
refers to: ANG
t statistic: 6.10339643019035

AKAP12 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.72646983333333
p value: 0.00343808277178911
refers to: AKAP12
refers to: 227529_s_at
t statistic: 7.7985305592593

KRTAP2-3 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.42577233333333
p value: 0.00249677400740996
refers to: 1555673_at
refers to: KRTAP2-3
t statistic: 8.7289956588672

MAMDC2
type: EnsemblDatabaseReference

NR5A2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.95779573333333
p value: 0.00257443986951362
refers to: 208343_s_at
refers to: NR5A2
t statistic: -8.61020025675938

228698_at
type: EFO_0005072
part of: A-AFFY-44

225914_s_at
type: EFO_0005072
part of: A-AFFY-44

220416_at
type: EFO_0005072
part of: A-AFFY-44

RASSF8 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.36331543333333
p value: 0.0199075204009661
refers to: 225946_at
refers to: RASSF8
t statistic: -4.16607602007866

PDK3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0363394
p value: 0.0138611960867821
refers to: PDK3
refers to: 206347_at
t statistic: -4.90445594337371

SVIP
type: EnsemblDatabaseReference

(Sample) cell line/HepG2
type: EFO_0001187
property type: cell line
property value: HepG2

ENDOD1
type: EnsemblDatabaseReference

EDNRB DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.60898586666667
p value: 0.0309525328863726
refers to: EDNRB
refers to: 204273_at
t statistic: -3.66495272421199

HRG DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.06541936666667
p value: 0.0181758314457877
refers to: 31835_at
refers to: HRG
t statistic: -4.33628007221594

LCOR DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0994395
p value: 0.0103437837449722
refers to: 226520_at
refers to: LCOR
t statistic: -5.13597763501222

(Sample) genotype/Tmprss6 mutant
type: EFO_0000001
property type: genotype
property value: Tmprss6 mutant

201009_s_at
type: EFO_0005072
part of: A-AFFY-44

208343_s_at
type: EFO_0005072
part of: A-AFFY-44

NR5A2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.24685766666667
p value: 0.0155642004100281
refers to: 210174_at
refers to: NR5A2
t statistic: -4.49392342309776

GPRC5A
type: EnsemblDatabaseReference

210372_s_at
type: EFO_0005072
part of: A-AFFY-44

1560785_at
type: EFO_0005072
part of: A-AFFY-44

PDK3
type: EnsemblDatabaseReference

204802_at
type: EFO_0005072
part of: A-AFFY-44

1555673_at
type: EFO_0005072
part of: A-AFFY-44

LRRC40
type: EnsemblDatabaseReference

SEMA4D DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2891725
p value: 0.0134763427738265
refers to: SEMA4D
refers to: 203528_at
t statistic: -4.71462861982952

(Factor value) GENOTYPE/empty vector
type: EFO_0000001
property type: GENOTYPE
property value: empty vector

SPP1
type: EnsemblDatabaseReference

MAMDC2
type: EnsemblDatabaseReference

TIMP4
type: EnsemblDatabaseReference

MATN2
type: EnsemblDatabaseReference

218901_at
type: EFO_0005072
part of: A-AFFY-44

PRRG4
type: EnsemblDatabaseReference

HRG DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.9751668
p value: 0.0120780185134124
refers to: 206226_at
refers to: HRG
t statistic: -5.51389689050309

206347_at
type: EFO_0005072
part of: A-AFFY-44

201416_at
type: EFO_0005072
part of: A-AFFY-44

MICAL2
type: EnsemblDatabaseReference

SPATA16
type: EnsemblDatabaseReference

TSC22D3
type: EnsemblDatabaseReference

IER5
type: EnsemblDatabaseReference

MYLK4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.672704
p value: 0.0125865940411755
refers to: MYLK4
refers to: 1556136_at
t statistic: -5.36684246080054

CDH16
type: EnsemblDatabaseReference

GPRC5A
type: EnsemblDatabaseReference

205939_at
type: EFO_0005072
part of: A-AFFY-44

ANG
type: EnsemblDatabaseReference

229614_at
type: EFO_0005072
part of: A-AFFY-44

EDNRB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.70183863333333
p value: 0.0330032334271059
refers to: 206701_x_at
refers to: EDNRB
t statistic: -3.43553286162592

205559_s_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) HepG2_Vector_rep1
type: Assay
has participant: A-AFFY-44

211668_s_at
type: EFO_0005072
part of: A-AFFY-44

TMPRSS6
type: EnsemblDatabaseReference

LCOR
type: EnsemblDatabaseReference

SEMA4D
type: EnsemblDatabaseReference

PCSK5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4453446
p value: 0.00688223234484473
refers to: PCSK5
refers to: 205560_at
t statistic: -5.89383275600358

FGA UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.36356133333334
p value: 0.00921835238655326
refers to: FGA
refers to: 205650_s_at
t statistic: 7.80829794370517

NR5A2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5524851
p value: 0.0142443936202404
refers to: NR5A2
refers to: 210174_at
t statistic: -4.84268846500626

PDK3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12625576666667
p value: 0.00630846339535897
refers to: PDK3
refers to: 206348_s_at
t statistic: -6.20313164521947

214234_s_at
type: EFO_0005072
part of: A-AFFY-44

AKAP12 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.30311973333333
p value: 0.00940064469931604
refers to: AKAP12
refers to: 227530_at
t statistic: 7.37117976992782

ENDOD1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19227213333333
p value: 0.0158324474049419
refers to: 212573_at
refers to: ENDOD1
t statistic: -4.56917647270762

ALDH8A1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.88967853333333
p value: 0.0410504497747787
refers to: ALDH8A1
refers to: 220148_at
t statistic: -3.36647985097135

PRRG4
type: EnsemblDatabaseReference

NUAK1
type: EnsemblDatabaseReference

GBP2
type: EnsemblDatabaseReference

NFIB
type: EnsemblDatabaseReference

LCP1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.40733623333333
p value: 0.00514788202798173
refers to: LCP1
refers to: 208885_at
t statistic: -9.93604335574837

TPD52L1
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.8858577
p value: 0.00961074556106054
refers to: 235489_at
refers to: RHOJ
t statistic: -7.01416771128437

KCNK3
type: EnsemblDatabaseReference

LCOR DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.26915233333333
p value: 0.0142449799958815
refers to: LCOR
refers to: 228454_at
t statistic: -4.8259693956137

UCP1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14587863333334
p value: 0.0106380565962897
refers to: UCP1
refers to: 221384_at
t statistic: -5.08096823981256

EHF
type: EnsemblDatabaseReference

AXL
type: EnsemblDatabaseReference

TIMP4 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.645711
p value: 0.0215082151080766
refers to: 206243_at
refers to: TIMP4
t statistic: -4.07680527556642

CDH16
type: EnsemblDatabaseReference

GS1-358P8.4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0632793
p value: 0.0102940343870713
refers to: GS1-358P8.4
refers to: 228959_at
t statistic: -6.68578059694018

ANG
type: EnsemblDatabaseReference

KRT23
type: EnsemblDatabaseReference

EHF DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.51113493333333
p value: 0.0156680052898843
refers to: EHF
refers to: 225645_at
t statistic: -4.58071777915657

206701_x_at
type: EFO_0005072
part of: A-AFFY-44

GS1-358P8.4
type: EnsemblDatabaseReference

205479_s_at
type: EFO_0005072
part of: A-AFFY-44

CP UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.16667376666667
p value: 0.00977629501062555
refers to: CP
refers to: 227253_at
t statistic: 6.86622270347237

PLAU DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12305666666667
p value: 0.0186324195548136
refers to: PLAU
refers to: 205479_s_at
t statistic: -4.30772094024977

MYLK4
type: EnsemblDatabaseReference

UCP1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20931463333333
p value: 0.0119209668692952
refers to: UCP1
refers to: 221384_at
t statistic: -5.61866242587826

RHOJ
type: EnsemblDatabaseReference

MYZAP
type: EnsemblDatabaseReference

SLC5A3
type: EnsemblDatabaseReference

SLC4A3
type: EnsemblDatabaseReference

SOWAHA DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1739481
p value: 0.011550701211981
refers to: 230238_at
refers to: SOWAHA
t statistic: -6.03995837144319

203108_at
type: EFO_0005072
part of: A-AFFY-44

211843_x_at
type: EFO_0005072
part of: A-AFFY-44

201280_s_at
type: EFO_0005072
part of: A-AFFY-44

EHF
type: EnsemblDatabaseReference

AXL
type: EnsemblDatabaseReference

SYNE1
type: EnsemblDatabaseReference

1553243_at
type: EFO_0005072
part of: A-AFFY-44

CAB39L DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18480733333333
p value: 0.0120780185134124
refers to: CAB39L
refers to: 225914_s_at
t statistic: -5.47981842237917

GC DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -4.4007531
p value: 0.0109387824027848
refers to: GC
refers to: 204965_at
t statistic: -6.34872267220995

AGR2 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 2.18922356666667
p value: 6.55137211533235E-5
refers to: 209173_at
refers to: AGR2
t statistic: 16.9769815409915

224797_at
type: EFO_0005072
part of: A-AFFY-44

CYR61 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.33945823333334
p value: 0.0014692078110688
refers to: CYR61
refers to: 210764_s_at
t statistic: 9.83856894049419

KRT23
type: EnsemblDatabaseReference

RP11-295M3.4
type: EnsemblDatabaseReference

DYRK3
type: EnsemblDatabaseReference

PAPPA DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.39766806666667
p value: 0.0164119610206267
refers to: PAPPA
refers to: 228128_x_at
t statistic: -4.50672787583432

HSPB8
type: EnsemblDatabaseReference

ALDH8A1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.28840743333333
p value: 0.0243169244460773
refers to: ALDH8A1
refers to: 220148_at
t statistic: -3.84671589023072

LCP1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.21056166666667
p value: 0.00112902248333888
refers to: LCP1
refers to: 208885_at
t statistic: -10.3218107142662

GLS DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.07370833333333
p value: 0.0221726414792452
refers to: GLS
refers to: 203158_s_at
t statistic: -4.03019017309187

TPD52L1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.54428386666667
p value: 0.0233261421901841
refers to: TPD52L1
refers to: 203786_s_at
t statistic: -3.9121877609462

PAPPA
type: EnsemblDatabaseReference

THBS1
type: EnsemblDatabaseReference

218611_at
type: EFO_0005072
part of: A-AFFY-44

GULP1
type: EnsemblDatabaseReference

228568_at
type: EFO_0005072
part of: A-AFFY-44

202992_at
type: EFO_0005072
part of: A-AFFY-44

RMDN2
type: EnsemblDatabaseReference

OSBPL1A
type: EnsemblDatabaseReference

213032_at
type: EFO_0005072
part of: A-AFFY-44

210192_at
type: EFO_0005072
part of: A-AFFY-44

KRTAP3-1 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.1617864
p value: 3.19399714411929E-4
refers to: KRTAP3-1
refers to: 233537_at
t statistic: 13.4647688656006

ABCA5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12666916666666
p value: 0.0127782310532446
refers to: ABCA5
refers to: 213353_at
t statistic: -4.80398675367949

1555233_at
type: EFO_0005072
part of: A-AFFY-44

202686_s_at
type: EFO_0005072
part of: A-AFFY-44

FAM167B DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23085103333334
p value: 0.0072308012382846
refers to: 223657_at
refers to: FAM167B
t statistic: -5.80445077527006

C7
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4288264
p value: 0.00680693088148211
refers to: RHOJ
refers to: 235489_at
t statistic: -5.98209492364534

SOX4
type: EnsemblDatabaseReference

DUSP5
type: EnsemblDatabaseReference

209457_at
type: EFO_0005072
part of: A-AFFY-44

SOX5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03021186666666
p value: 0.00414261515156918
refers to: SOX5
refers to: 1569638_at
t statistic: -7.29062385821087

NUAK1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27115766666667
p value: 0.0119209668692952
refers to: NUAK1
refers to: 204589_at
t statistic: -5.74838267727288

PCSK5
type: EnsemblDatabaseReference

PTGS1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.66788013333333
p value: 0.0208491310834143
refers to: 215813_s_at
refers to: PTGS1
t statistic: -4.11802783184428

ITIH5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15683753333334
p value: 0.0124624923609546
refers to: 1553243_at
refers to: ITIH5
t statistic: -5.37998665210926

SPATA16 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.8602941
p value: 0.0128793161488187
refers to: 223876_at
refers to: SPATA16
t statistic: -5.06482042177762

CEP55
type: EnsemblDatabaseReference

SLC7A10
type: EnsemblDatabaseReference

SLC22A16
type: EnsemblDatabaseReference

1553313_s_at
type: EFO_0005072
part of: A-AFFY-44

210764_s_at
type: EFO_0005072
part of: A-AFFY-44

RRAD
type: EnsemblDatabaseReference

AREG UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.23315643333333
p value: 0.00352063999373558
refers to: AREG
refers to: 205239_at
t statistic: 7.6603509041809

CDH16 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.22420066666667
p value: 0.0128425207028045
refers to: CDH16
refers to: 206517_at
t statistic: -5.17595923333257

232232_s_at
type: EFO_0005072
part of: A-AFFY-44

THBS1
type: EnsemblDatabaseReference

ZNF320
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.61762963333333
p value: 0.0116793863845909
refers to: RHOJ
refers to: 238906_s_at
t statistic: -5.97666070406932

S1PR3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0318634
p value: 0.0224584462295331
refers to: S1PR3
refers to: 228176_at
t statistic: -3.96084982178025

ABCA5
type: EnsemblDatabaseReference

203914_x_at
type: EFO_0005072
part of: A-AFFY-44

AXL UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.10361826666667
p value: 0.0058174339229464
refers to: AXL
refers to: 202686_s_at
t statistic: 6.36690040200734

TXNIP UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.06653973333333
p value: 0.0085824037614459
refers to: 201010_s_at
refers to: TXNIP
t statistic: 5.4459860398864

205645_at
type: EFO_0005072
part of: A-AFFY-44

225815_at
type: EFO_0005072
part of: A-AFFY-44

SLC4A11 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.578787
p value: 0.0119209668692952
refers to: SLC4A11
refers to: 223748_at
t statistic: -5.84313285540346

CAB39L
type: EnsemblDatabaseReference

205547_s_at
type: EFO_0005072
part of: A-AFFY-44

DUSP5
type: EnsemblDatabaseReference

204237_at
type: EFO_0005072
part of: A-AFFY-44

DAB1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20547213333333
p value: 0.0147270332455329
refers to: DAB1
refers to: 228329_at
t statistic: -4.72619353120635

212657_s_at
type: EFO_0005072
part of: A-AFFY-44

DYRK3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.6371723
p value: 0.0154702782599573
refers to: 1560785_at
refers to: DYRK3
t statistic: -4.60707271214278

SLC22A16 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.30395076666667
p value: 0.0194623322639778
refers to: 232232_s_at
refers to: SLC22A16
t statistic: -4.19728100163274

CEP55
type: EnsemblDatabaseReference

215813_s_at
type: EFO_0005072
part of: A-AFFY-44

GBP2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16383173333333
p value: 0.012944897288452
refers to: 242907_at
refers to: GBP2
t statistic: -4.76589615799186

GC
type: EnsemblDatabaseReference

ATP8A1
type: EnsemblDatabaseReference

RRAD
type: EnsemblDatabaseReference

SLC6A12
type: EnsemblDatabaseReference

MCHR1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.65325266666667
p value: 0.0128336678848728
refers to: MCHR1
refers to: 230498_at
t statistic: -5.18444743629258

AKAP12 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3666565
p value: 0.00961074556106054
refers to: AKAP12
refers to: 210517_s_at
t statistic: 7.03088116836961

226520_at
type: EFO_0005072
part of: A-AFFY-44

220625_s_at
type: EFO_0005072
part of: A-AFFY-44

205141_at
type: EFO_0005072
part of: A-AFFY-44

ITIH5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09494323333333
p value: 0.0099622088882798
refers to: ITIH5
refers to: 1553243_at
t statistic: -5.20162247560841

CP UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.26112983333333
p value: 0.0173840314059357
refers to: 1558034_s_at
refers to: CP
t statistic: 4.40898158307669

IL11
type: EnsemblDatabaseReference

LRBA
type: EnsemblDatabaseReference

220148_at
type: EFO_0005072
part of: A-AFFY-44

227529_s_at
type: EFO_0005072
part of: A-AFFY-44

CYP3A5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.10486813333333
p value: 0.0131198845291354
refers to: CYP3A5
refers to: 205765_at
t statistic: -5.00679318987215

GLS DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.36407983333334
p value: 0.0127147595529134
refers to: GLS
refers to: 203157_s_at
t statistic: -5.25988135546165

ATP8B4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.28588663333333
p value: 0.0166062048418327
refers to: 220416_at
refers to: ATP8B4
t statistic: -4.46683208062382

KCNK3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.17259006666667
p value: 0.00921835238655326
refers to: 205952_at
refers to: KCNK3
t statistic: -7.88060519362152

ATP8A1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.07726076666666
p value: 0.023862466953849
refers to: ATP8A1
refers to: 210192_at
t statistic: -3.87748336925747

CPLX2
type: EnsemblDatabaseReference

LCOR DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.25652733333333
p value: 0.0119209668692952
refers to: LCOR
refers to: 226520_at
t statistic: -5.6887393919627

HRG
type: EnsemblDatabaseReference

PLAU
type: EnsemblDatabaseReference

TNFSF14
type: EnsemblDatabaseReference

ARRDC3
type: EnsemblDatabaseReference

CYP3A5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08931956666667
p value: 0.016126241885227
refers to: CYP3A5
refers to: 214235_at
t statistic: -4.53566313253549

DAB1
type: EnsemblDatabaseReference

DYRK3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27014306666667
p value: 0.030925018258094
refers to: 1560785_at
refers to: DYRK3
t statistic: -3.66608040734071

238906_s_at
type: EFO_0005072
part of: A-AFFY-44

CLCN4
type: EnsemblDatabaseReference

CYP3A7 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18305643333333
p value: 0.0148037938835517
refers to: 205939_at
refers to: CYP3A7
t statistic: -4.70254963709513

CYP3A5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08799743333333
p value: 0.0225336335773216
refers to: 214234_s_at
refers to: CYP3A5
t statistic: -3.9550428403525

204803_s_at
type: EFO_0005072
part of: A-AFFY-44

CYP3A4
type: EnsemblDatabaseReference

SOX7 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20390086666666
p value: 0.0095270011428797
refers to: SOX7
refers to: 228698_at
t statistic: -5.26351489788319

NADK2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.14936266666666
p value: 0.025219225497946
refers to: 229299_at
refers to: NADK2
t statistic: -3.78625310236472

202350_s_at
type: EFO_0005072
part of: A-AFFY-44

DCLRE1B DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23502493333333
p value: 0.0119209668692952
refers to: DCLRE1B
refers to: 219490_s_at
t statistic: -5.90413117895838

MATN2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.02883253333333
p value: 0.0493467147925628
refers to: MATN2
refers to: 202350_s_at
t statistic: -3.18305284812229

CYP3A4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.2801234
p value: 0.0138574555372986
refers to: CYP3A4
refers to: 205999_x_at
t statistic: -4.91374995636103

ALDH8A1
type: EnsemblDatabaseReference

CXCL8 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 2.1868055
p value: 5.48350402415202E-6
refers to: CXCL8
refers to: 202859_x_at
t statistic: 23.15366365823

SVIP DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04196333333334
p value: 0.0177667772867024
refers to: 226278_at
refers to: SVIP
t statistic: -4.37445058088766

NR5A2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04790646666667
p value: 0.0149491238099009
refers to: 208337_s_at
refers to: NR5A2
t statistic: -4.5637347932427

230238_at
type: EFO_0005072
part of: A-AFFY-44

PLSCR4
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0407996
p value: 0.0175736678138114
refers to: RHOJ
refers to: 243481_at
t statistic: -4.39064155344593

SEMA4D DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.5863654
p value: 0.0128425207028045
refers to: SEMA4D
refers to: 203528_at
t statistic: -5.1438205355525

NEXN
type: EnsemblDatabaseReference

224919_at
type: EFO_0005072
part of: A-AFFY-44

ANKRD1
type: EnsemblDatabaseReference

ATP8B4
type: EnsemblDatabaseReference

228329_at
type: EFO_0005072
part of: A-AFFY-44

204271_s_at
type: EFO_0005072
part of: A-AFFY-44

CYR61
type: EnsemblDatabaseReference

PLAU
type: EnsemblDatabaseReference

C7 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18074763333333
p value: 0.00950890195292702
refers to: C7
refers to: 202992_at
t statistic: -5.26791753363323

234367_x_at
type: EFO_0005072
part of: A-AFFY-44

CLCN4
type: EnsemblDatabaseReference

SLC6A12 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.47097866666667
p value: 0.0120780185134124
refers to: 206058_at
refers to: SLC6A12
t statistic: -5.5242645971353

226946_at
type: EFO_0005072
part of: A-AFFY-44

208323_s_at
type: EFO_0005072
part of: A-AFFY-44

IER5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.03176366666667
p value: 0.0144659723687486
refers to: IER5
refers to: 218611_at
t statistic: -4.7652029705341

GLS
type: EnsemblDatabaseReference

HIST1H2BD
type: EnsemblDatabaseReference

TMPRSS6 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 4.41244903333334
p value: 3.27456781010893E-6
refers to: TMPRSS6
refers to: 234367_x_at
t statistic: 25.7870414098135

TPD52L1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.44447873333333
p value: 0.034279339731622
refers to: 210372_s_at
refers to: TPD52L1
t statistic: -3.38783247113817

213353_at
type: EFO_0005072
part of: A-AFFY-44

(Assay) HepG2_mutant Tmprss6_rep3
type: Assay
identifier: HepG2_mutant Tmprss6_rep3
has participant: A-AFFY-44

CAPN8 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.10682993333333
p value: 0.0213887764392488
refers to: CAPN8
refers to: 229030_at
t statistic: -4.0435417443104

222271_at
type: EFO_0005072
part of: A-AFFY-44

205952_at
type: EFO_0005072
part of: A-AFFY-44

227253_at
type: EFO_0005072
part of: A-AFFY-44

CTGF
type: EnsemblDatabaseReference

233550_s_at
type: EFO_0005072
part of: A-AFFY-44

206029_at
type: EFO_0005072
part of: A-AFFY-44

PLSCR4 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.40214853333333
p value: 0.00686259184598237
refers to: PLSCR4
refers to: 218901_at
t statistic: 8.41859457755883

229030_at
type: EFO_0005072
part of: A-AFFY-44

CP
type: EnsemblDatabaseReference

RP11-295M3.4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.624445
p value: 0.0140580976742758
refers to: RP11-295M3.4
refers to: 222271_at
t statistic: -4.87552981867315

EDNRB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.91220336666667
p value: 0.030389932754947
refers to: EDNRB
refers to: 204271_s_at
t statistic: -3.54111890035345

TXNIP
type: EnsemblDatabaseReference

TAGLN
type: EnsemblDatabaseReference

205302_at
type: EFO_0005072
part of: A-AFFY-44

MCHR1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08653756666666
p value: 0.0104044962865329
refers to: 221354_s_at
refers to: MCHR1
t statistic: -6.63850186624606

PTGS1
type: EnsemblDatabaseReference

206226_at
type: EFO_0005072
part of: A-AFFY-44

233537_at
type: EFO_0005072
part of: A-AFFY-44

GC DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -3.7477491
p value: 0.00849126652141931
refers to: GC
refers to: 204965_at
t statistic: -5.5344597074292

OSBPL1A DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7209109
p value: 0.0138559696740893
refers to: OSBPL1A
refers to: 209485_s_at
t statistic: -4.91942076445127

230498_at
type: EFO_0005072
part of: A-AFFY-44

E-GEOD-10591
type: microarray 1colour mrna differential
RO_0002162: Homo sapiens
description: TMPRSS6 is a type II transmembrane serine protease and is revealed by our work to be part of a low-iron sensing pathway. When animal gets iron deficient, TMPRSS6 is required to shut off hepcidin gene, so as to allow iron to be uptaken from GI tract. The mutant mouse, which was generated by ENU mutagenesis, has developed microcytic anemia. The phenotype is caused by a splicing error in Tmprss6 gene. However, the mechanism of TMPRSS6 effect remains elusive. To gain further insight into the molecular components of the TMPRSS6 signaling pathway, we overexpressed either TMPRSS6 or its mutant version of protein in human liver carcinoma cell line HepG2 cells, and compared the transcription status betweem these two treatments. Experiment Overall Design: Triplicate per transfection with wildtype Tmprss6 cDNA, mutant version of Tmprss6 cDNA and empty vector as control, respectively. 36 hours post transfection, cells were harvested and subjected to RNA extraction.
uses data from: http://identifiers.org/pubmed/18451267

EDN1
type: EnsemblDatabaseReference

244070_at
type: EFO_0005072
part of: A-AFFY-44

CLCN4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.047548
p value: 0.0128793161488187
refers to: CLCN4
refers to: 214769_at
t statistic: -5.08877632421166

TPD52L1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18100013333333
p value: 0.0337613119626858
refers to: 203786_s_at
refers to: TPD52L1
t statistic: -3.55813974597712

GBP2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.32744
p value: 0.0148037938835517
refers to: GBP2
refers to: 242907_at
t statistic: -4.6931158525729

205649_s_at
type: EFO_0005072
part of: A-AFFY-44

SVIP
type: EnsemblDatabaseReference

LCOR DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.07656166666667
p value: 0.0156704668664572
refers to: LCOR
refers to: 228454_at
t statistic: -4.48363161665066

NR5A2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16016733333333
p value: 0.0210358601486639
refers to: NR5A2
refers to: 208337_s_at
t statistic: -4.06218469496062

203786_s_at
type: EFO_0005072
part of: A-AFFY-44

TSC22D3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15330866666667
p value: 0.00296191033903973
refers to: TSC22D3
refers to: 208763_s_at
t statistic: -8.05250390376934

RHOJ DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.09015906666667
p value: 0.0109992414105332
refers to: RHOJ
refers to: 1555233_at
t statistic: -5.00208842190626

CRYAB
type: EnsemblDatabaseReference

DAB2
type: EnsemblDatabaseReference

PTGS1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.83729936666667
p value: 0.0161495786864605
refers to: PTGS1
refers to: 215813_s_at
t statistic: -4.53082022066192

ARRDC3 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.19797156666667
p value: 4.54373989165915E-4
refers to: 224797_at
refers to: ARRDC3
t statistic: 12.1898401074949

(Assay) HepG2_Tmprss6_rep2
type: Assay
has participant: A-AFFY-44

DCLRE1B DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.20231796666666
p value: 0.0085824037614459
refers to: DCLRE1B
refers to: 222889_at
t statistic: -5.43955429781468

HPGD
type: EnsemblDatabaseReference

GLS DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.47184183333333
p value: 0.0128425207028045
refers to: GLS
refers to: 203158_s_at
t statistic: -5.16784273228927

THBS1 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.26011393333333
p value: 0.011849839385658
refers to: 201109_s_at
refers to: THBS1
t statistic: 5.91970895989778

PDK3
type: EnsemblDatabaseReference

DCLRE1B
type: EnsemblDatabaseReference

GULP1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.69721223333333
p value: 0.0128425207028045
refers to: GULP1
refers to: 204237_at
t statistic: -5.11539049043741

THBS1 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.14460416666667
p value: 0.00921835238655326
refers to: THBS1
refers to: 201110_s_at
t statistic: 7.65013313414778

205765_at
type: EFO_0005072
part of: A-AFFY-44

KCNK3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.57917136666667
p value: 0.00251151839602061
refers to: KCNK3
refers to: 205952_at
t statistic: -8.69697363507382

31835_at
type: EFO_0005072
part of: A-AFFY-44

NADK2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.12428166666667
p value: 0.0144659723687486
refers to: NADK2
refers to: 226946_at
t statistic: -4.77266940335532

RAMP1
type: EnsemblDatabaseReference

211506_s_at
type: EFO_0005072
part of: A-AFFY-44

EDNRB DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7319852
p value: 0.0354643315726596
refers to: EDNRB
refers to: 206701_x_at
t statistic: -3.50963495164843

MICAL2
type: EnsemblDatabaseReference

SPATA16
type: EnsemblDatabaseReference

218542_at
type: EFO_0005072
part of: A-AFFY-44

202859_x_at
type: EFO_0005072
part of: A-AFFY-44

LRBA DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.35453283333333
p value: 0.0144045517407371
refers to: LRBA
refers to: 212692_s_at
t statistic: -4.80125178670246

TXNIP UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.223718
p value: 0.0128793161488187
refers to: TXNIP
refers to: 201008_s_at
t statistic: 5.06513902694158

238513_at
type: EFO_0005072
part of: A-AFFY-44

IER5
type: EnsemblDatabaseReference

209173_at
type: EFO_0005072
part of: A-AFFY-44

CRYAB
type: EnsemblDatabaseReference

221354_s_at
type: EFO_0005072
part of: A-AFFY-44

CEP55 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.7779242
p value: 0.0120780185134124
refers to: CEP55
refers to: 218542_at
t statistic: -5.48094799654811

REPS2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27064416666667
p value: 0.00448157085600792
refers to: REPS2
refers to: 205645_at
t statistic: -6.9555795982008

210174_at
type: EFO_0005072
part of: A-AFFY-44

AQP3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.38454383333334
p value: 0.0120780185134124
refers to: AQP3
refers to: 39248_at
t statistic: -5.49739326588263

REPS2
type: EnsemblDatabaseReference

HPGD
type: EnsemblDatabaseReference

DUSP5 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.55791603333333
p value: 4.58911760358684E-4
refers to: 209457_at
refers to: DUSP5
t statistic: 12.0019806554198

203372_s_at
type: EFO_0005072
part of: A-AFFY-44

203157_s_at
type: EFO_0005072
part of: A-AFFY-44

FGA
type: EnsemblDatabaseReference

PRRG4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0464282
p value: 0.0271752146716457
refers to: PRRG4
refers to: 207291_at
t statistic: -3.68998937575573

EDNRB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.61781203333333
p value: 0.0272914737140345
refers to: EDNRB
refers to: 204273_at
t statistic: -3.67965720946337

KRTAP3-1
type: EnsemblDatabaseReference

PCSK5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.44471813333333
p value: 0.0107358004243465
refers to: PCSK5
refers to: 213652_at
t statistic: -5.06292465821124

HPGD DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0860846
p value: 0.0424941458100911
refers to: HPGD
refers to: 203914_x_at
t statistic: -3.33105465029051

NFIB
type: EnsemblDatabaseReference

CYP3A7
type: EnsemblDatabaseReference

205560_at
type: EFO_0005072
part of: A-AFFY-44

CYP3A7 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19744183333333
p value: 0.0124471469794205
refers to: 211843_x_at
refers to: CYP3A7
t statistic: -5.41317403013949

TPD52L1
type: EnsemblDatabaseReference

TMEM27 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4591003
p value: 0.0296674692229705
refers to: 223784_at
refers to: TMEM27
t statistic: -3.56907430893322

ANKRD1 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.524338
p value: 0.00429226124574171
refers to: ANKRD1
refers to: 206029_at
t statistic: 7.16032236682336

TAGLN UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01809316666667
p value: 7.7275062340866E-4
refers to: TAGLN
refers to: 205547_s_at
t statistic: 11.1174777412225

SYNE1 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.2687924
p value: 3.21777072595766E-4
refers to: SYNE1
refers to: 244070_at
t statistic: 13.2991523421675

TXNIP UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.3189339
p value: 0.0109387824027848
refers to: TXNIP
refers to: 201010_s_at
t statistic: 6.43875983341396

NFIB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0093632
p value: 0.0138241645712575
refers to: NFIB
refers to: 213032_at
t statistic: -4.92271770258218

GLS DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.19429933333333
p value: 0.0123550768489902
refers to: 203159_at
refers to: GLS
t statistic: -5.42729975001072

220868_s_at
type: EFO_0005072
part of: A-AFFY-44

203158_s_at
type: EFO_0005072
part of: A-AFFY-44

RAMP1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.00423666666667
p value: 0.00921835238655326
refers to: 204916_at
refers to: RAMP1
t statistic: -7.65371959810011

SSTR2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0922957
p value: 0.0119209668692952
refers to: SSTR2
refers to: 217455_s_at
t statistic: -5.71371604727

MYLK4
type: EnsemblDatabaseReference

LRBA DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.21372366666667
p value: 0.0169468397800761
refers to: LRBA
refers to: 212692_s_at
t statistic: -4.36934762580815

KRTAP3-1
type: EnsemblDatabaseReference

NR5A2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.24318593333333
p value: 0.00731109677480358
refers to: NR5A2
refers to: 208343_s_at
t statistic: -8.30206407374056

1552309_a_at
type: EFO_0005072
part of: A-AFFY-44

SLC5A3
type: EnsemblDatabaseReference

MATN2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.27223716666667
p value: 0.0271639612753433
refers to: 202350_s_at
refers to: MATN2
t statistic: -3.69113481883056

CXCL8
type: EnsemblDatabaseReference

ETNPPL DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.264754
p value: 0.00687894872122464
refers to: 221008_s_at
refers to: ETNPPL
t statistic: -5.90768132715941

ETNPPL DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.14957933333334
p value: 0.0144045517407371
refers to: ETNPPL
refers to: 221008_s_at
t statistic: -4.7904034182284

PLAU DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18405633333333
p value: 0.0128793161488187
refers to: 211668_s_at
refers to: PLAU
t statistic: -5.07254533870168

219490_s_at
type: EFO_0005072
part of: A-AFFY-44

204916_at
type: EFO_0005072
part of: A-AFFY-44

LINC00973 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.40693453333333
p value: 0.0049704462968629
refers to: LINC00973
refers to: 242005_at
t statistic: 6.75171326238974

FAM167B
type: EnsemblDatabaseReference

FGA UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08700183333333
p value: 4.54373989165915E-4
refers to: FGA
refers to: 205649_s_at
t statistic: 12.3008485520631

209485_s_at
type: EFO_0005072
part of: A-AFFY-44

IGFBP1
type: EnsemblDatabaseReference

201417_at
type: EFO_0005072
part of: A-AFFY-44

209283_at
type: EFO_0005072
part of: A-AFFY-44

SOX7
type: EnsemblDatabaseReference

225645_at
type: EFO_0005072
part of: A-AFFY-44

IL1RN UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.13589433333334
p value: 0.0127147595529134
refers to: IL1RN
refers to: 212657_s_at
t statistic: 5.33617531546123

PDK3 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1081883
p value: 0.00457004990674794
refers to: 221957_at
refers to: PDK3
t statistic: -6.87774958006615

SOX4 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.24935363333333
p value: 0.00514788202798173
refers to: SOX4
refers to: 201416_at
t statistic: 9.93255350909589

204965_at
type: EFO_0005072
part of: A-AFFY-44

CYR61 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.17857333333333
p value: 4.54373989165915E-4
refers to: CYR61
refers to: 201289_at
t statistic: 12.3480493718487

DCLRE1B DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.42851853333333
p value: 0.0119569494246076
refers to: DCLRE1B
refers to: 222889_at
t statistic: -5.55582654203573

RMDN2
type: EnsemblDatabaseReference

RMDN2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23985026666667
p value: 0.0222996438932851
refers to: RMDN2
refers to: 235349_at
t statistic: -3.97986784970225

MCHR1
type: EnsemblDatabaseReference

HSPB8 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.23819353333333
p value: 0.0268882886605901
refers to: 221667_s_at
refers to: HSPB8
t statistic: -3.70140194410414

MCHR1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0076781
p value: 0.0250172082727921
refers to: MCHR1
refers to: 223855_s_at
t statistic: -3.80895764153195

RRAD DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.3533757
p value: 0.0116793863845909
refers to: RRAD
refers to: 204803_s_at
t statistic: -5.97921642735018

SLC4A3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.68631223333333
p value: 0.00961074556106054
refers to: SLC4A3
refers to: 205918_at
t statistic: -7.01301137256894

TMEM27
type: EnsemblDatabaseReference

203159_at
type: EFO_0005072
part of: A-AFFY-44

NADK2
type: EnsemblDatabaseReference

201008_s_at
type: EFO_0005072
part of: A-AFFY-44

228959_at
type: EFO_0005072
part of: A-AFFY-44

243481_at
type: EFO_0005072
part of: A-AFFY-44

ANXA13
type: EnsemblDatabaseReference

LINC00973
type: EnsemblDatabaseReference

205239_at
type: EFO_0005072
part of: A-AFFY-44

SOX5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1574698
p value: 0.0119209668692952
refers to: 207336_at
refers to: SOX5
t statistic: -5.86980804260102

SLC5A3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.32069833333333
p value: 0.0256773427327046
refers to: SLC5A3
refers to: 213167_s_at
t statistic: -3.76547676991225

NR5A2
type: EnsemblDatabaseReference

SLC22A16 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -2.19085933333333
p value: 0.0219928635262685
refers to: SLC22A16
refers to: 232232_s_at
t statistic: -4.04870447331729

PCSK5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.73393916666667
p value: 0.00965826955641655
refers to: PCSK5
refers to: 205560_at
t statistic: -6.93959172925163

221384_at
type: EFO_0005072
part of: A-AFFY-44

SLC22A16
type: EnsemblDatabaseReference

AKAP12
type: EnsemblDatabaseReference

SLC7A10
type: EnsemblDatabaseReference

NFIB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00926823333333
p value: 0.0119209668692952
refers to: NFIB
refers to: 209289_at
t statistic: -5.66307765268508

MRPS6 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.052763
p value: 0.0130986923562325
refers to: MRPS6
refers to: 224919_at
t statistic: -5.02811935891367

NEXN UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02400356666667
p value: 0.00414261515156918
refers to: NEXN
refers to: 1552309_a_at
t statistic: 7.29156385330729

SOWAHA
type: EnsemblDatabaseReference

PAPPA DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1451964
p value: 0.0182123348397918
refers to: 224942_at
refers to: PAPPA
t statistic: -4.33089690711354

AREG UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.09797943333333
p value: 0.0102940343870713
refers to: AREG
refers to: 205239_at
t statistic: 6.73827993052926

SSTR2
type: EnsemblDatabaseReference

CAPN8
type: EnsemblDatabaseReference

CPLX2 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01170896666667
p value: 0.0148037938835517
refers to: CPLX2
refers to: 225815_at
t statistic: 4.6962468584528

226278_at
type: EFO_0005072
part of: A-AFFY-44

217455_s_at
type: EFO_0005072
part of: A-AFFY-44

ATP8A1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08666556666667
p value: 0.0252754204428153
refers to: 210192_at
refers to: ATP8A1
t statistic: -3.89250603341644

IGFBP1 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.66798466666667
p value: 0.0113176396342144
refers to: 205302_at
refers to: IGFBP1
t statistic: 6.15606075755989

PDK3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.49707223333333
p value: 0.00965826955641655
refers to: PDK3
refers to: 206348_s_at
t statistic: -6.92070121303828

228128_x_at
type: EFO_0005072
part of: A-AFFY-44

201110_s_at
type: EFO_0005072
part of: A-AFFY-44

223876_at
type: EFO_0005072
part of: A-AFFY-44

212573_at
type: EFO_0005072
part of: A-AFFY-44

CRYAB DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.60222503333333
p value: 0.0272914737140345
refers to: CRYAB
refers to: 209283_at
t statistic: -3.6768095638734

206243_at
type: EFO_0005072
part of: A-AFFY-44

CAB39L DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.156048
p value: 0.0149311233108376
refers to: CAB39L
refers to: 225915_at
t statistic: -4.67376474677431

(Sample) organism/Homo sapiens
type: Homo sapiens
property type: organism
property value: Homo sapiens

MAMDC2 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00941146666667
p value: 0.0342468334518604
refers to: MAMDC2
refers to: 228885_at
t statistic: -3.38946100884442

TSC22D3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.53184966666667
p value: 0.00921976488204102
refers to: TSC22D3
refers to: 208763_s_at
t statistic: -7.53091765258337

PCSK5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.88515036666667
p value: 0.011550701211981
refers to: PCSK5
refers to: 205559_s_at
t statistic: -6.01565325658167

214109_at
type: EFO_0005072
part of: A-AFFY-44

CDR2L DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.02514243333333
p value: 0.0146810167750397
refers to: CDR2L
refers to: 213230_at
t statistic: -4.73488533090019

GC
type: EnsemblDatabaseReference

212692_s_at
type: EFO_0005072
part of: A-AFFY-44

SLC6A12
type: EnsemblDatabaseReference

(Assay) HepG2_Vector_rep2
type: Assay
has participant: A-AFFY-44

ZNF320 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.18307816666667
p value: 0.0128297036865449
refers to: 229614_at
refers to: ZNF320
t statistic: -5.19575870339593

HPGD DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0558859
p value: 0.0222996438932851
refers to: 211548_s_at
refers to: HPGD
t statistic: -3.97764968623179

ENDOD1
type: EnsemblDatabaseReference

208885_at
type: EFO_0005072
part of: A-AFFY-44

RMDN2 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.08191343333333
p value: 0.0249466633666509
refers to: 235349_at
refers to: RMDN2
t statistic: -3.90683272462021

235349_at
type: EFO_0005072
part of: A-AFFY-44

222802_at
type: EFO_0005072
part of: A-AFFY-44

SSTR2
type: EnsemblDatabaseReference

PCSK5 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.500877
p value: 0.00801172086768659
refers to: PCSK5
refers to: 205559_s_at
t statistic: -5.63833292314624

RAMP1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.45972416666667
p value: 0.0027142709575249
refers to: RAMP1
refers to: 204916_at
t statistic: -8.49379685560079

208337_s_at
type: EFO_0005072
part of: A-AFFY-44

CPLX2
type: EnsemblDatabaseReference

ABCA5 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4337253
p value: 0.0121800655323317
refers to: 213353_at
refers to: ABCA5
t statistic: -5.45143514308359

C5
type: EnsemblDatabaseReference

ARRDC3
type: EnsemblDatabaseReference

SOCS2
type: EnsemblDatabaseReference

212473_s_at
type: EFO_0005072
part of: A-AFFY-44

LRRC40
type: EnsemblDatabaseReference

MICAL2 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.0273121
p value: 0.00607197399842315
refers to: 212473_s_at
refers to: MICAL2
t statistic: 6.28124443881163

SPP1
type: EnsemblDatabaseReference

224942_at
type: EFO_0005072
part of: A-AFFY-44

TIMP4
type: EnsemblDatabaseReference

207001_x_at
type: EFO_0005072
part of: A-AFFY-44

MATN2
type: EnsemblDatabaseReference

TMPRSS6 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 4.5254142
p value: 8.32226395629441E-6
refers to: TMPRSS6
refers to: 234367_x_at
t statistic: 24.2946968304163

206058_at
type: EFO_0005072
part of: A-AFFY-44

AGR2
type: EnsemblDatabaseReference

1569638_at
type: EFO_0005072
part of: A-AFFY-44

TSC22D3
type: EnsemblDatabaseReference

ALDH8A1
type: EnsemblDatabaseReference

LRRC40 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.70660616666667
p value: 0.0144045517407371
refers to: 218577_at
refers to: LRRC40
t statistic: -4.78934211369714

210517_s_at
type: EFO_0005072
part of: A-AFFY-44

201109_s_at
type: EFO_0005072
part of: A-AFFY-44

223784_at
type: EFO_0005072
part of: A-AFFY-44

EDNRB
type: EnsemblDatabaseReference

RRAD DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.364692
p value: 0.0119209668692952
refers to: 204802_at
refers to: RRAD
t statistic: -5.58596204980886

227530_at
type: EFO_0005072
part of: A-AFFY-44

PLSCR4
type: EnsemblDatabaseReference

218577_at
type: EFO_0005072
part of: A-AFFY-44

ARHGAP42 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1260526
p value: 0.0308119786017088
refers to: ARHGAP42
refers to: 230047_at
t statistic: -3.66990827625227

NEXN
type: EnsemblDatabaseReference

223855_s_at
type: EFO_0005072
part of: A-AFFY-44

228454_at
type: EFO_0005072
part of: A-AFFY-44

214769_at
type: EFO_0005072
part of: A-AFFY-44

204589_at
type: EFO_0005072
part of: A-AFFY-44

ELF5
type: EnsemblDatabaseReference

213230_at
type: EFO_0005072
part of: A-AFFY-44

ATP8B4
type: EnsemblDatabaseReference

225915_at
type: EFO_0005072
part of: A-AFFY-44

ANKRD1 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.28807293333333
p value: 0.0110549550813524
refers to: 206029_at
refers to: ANKRD1
t statistic: 6.23613361310816

221667_s_at
type: EFO_0005072
part of: A-AFFY-44

CYR61
type: EnsemblDatabaseReference

Analysis of 'Tmprss6 mutant' vs 'empty vector'
type: MicroarrayDifferentialExpressionAnalysis

C5
type: EnsemblDatabaseReference

TIMP4 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.69394073333333
p value: 0.0206237022383075
refers to: 206243_at
refers to: TIMP4
t statistic: -4.09654485684603

201289_at
type: EFO_0005072
part of: A-AFFY-44

SOCS2
type: EnsemblDatabaseReference

SEMA4D
type: EnsemblDatabaseReference

TMPRSS6
type: EnsemblDatabaseReference

LCOR
type: EnsemblDatabaseReference

(Factor value) GENOTYPE/Tmprss6 mutant
type: EFO_0000001
property type: GENOTYPE
property value: Tmprss6 mutant

ATP8A1 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.42745416666667
p value: 0.0119209668692952
refers to: ATP8A1
refers to: 213106_at
t statistic: -5.57029931251848

IL1RN
type: EnsemblDatabaseReference

221008_s_at
type: EFO_0005072
part of: A-AFFY-44

NUAK1
type: EnsemblDatabaseReference

GBP2
type: EnsemblDatabaseReference

RHOJ DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1240756
p value: 0.0189948885752983
refers to: RHOJ
refers to: 243481_at
t statistic: -4.22637299536134

AGR2
type: EnsemblDatabaseReference

GLS
type: EnsemblDatabaseReference

39248_at
type: EFO_0005072
part of: A-AFFY-44

C5 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01466566666666
p value: 0.0200470267314299
refers to: C5
refers to: 205500_at
t statistic: 4.15158155625522

HIST1H2BD
type: EnsemblDatabaseReference

218963_s_at
type: EFO_0005072
part of: A-AFFY-44

KCNK3
type: EnsemblDatabaseReference

PDK3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.40254263333333
p value: 0.00940064469931604
refers to: PDK3
refers to: 221957_at
t statistic: -7.30771043417923

EDNRB
type: EnsemblDatabaseReference

204273_at
type: EFO_0005072
part of: A-AFFY-44

(Sample) genotype/Tmprss6 wild type
type: EFO_0000001
property type: genotype
property value: Tmprss6 wild type

221957_at
type: EFO_0005072
part of: A-AFFY-44

211548_s_at
type: EFO_0005072
part of: A-AFFY-44

SPP1 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.01545
p value: 0.00940064469931604
refers to: SPP1
refers to: 209875_s_at
t statistic: 7.25030047239585

AREG
type: EnsemblDatabaseReference

SOX4 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.071587
p value: 0.00450772171473696
refers to: SOX4
refers to: 201417_at
t statistic: 6.90208640513668

ELF5
type: EnsemblDatabaseReference

GULP1 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.0887888
p value: 0.0408588755717922
refers to: GULP1
refers to: 204237_at
t statistic: -3.36994743761683

SLC4A11 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.47520953333333
p value: 0.0113176396342144
refers to: SLC4A11
refers to: 233550_s_at
t statistic: -6.13215732122278

206517_at
type: EFO_0005072
part of: A-AFFY-44

GS1-358P8.4
type: EnsemblDatabaseReference

DAB2 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.09688166666667
p value: 0.0128793161488187
refers to: DAB2
refers to: 201280_s_at
t statistic: 5.0909596630496

CTGF UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03821116666666
p value: 0.0127147595529134
refers to: 209101_at
refers to: CTGF
t statistic: 5.2051690032156

IL1RN
type: EnsemblDatabaseReference

205650_s_at
type: EFO_0005072
part of: A-AFFY-44

LRRC40 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15968766666667
p value: 0.0332458024433509
refers to: LRRC40
refers to: 218577_at
t statistic: -3.57991893507707

PTGS1
type: EnsemblDatabaseReference

A-AFFY-44
type: EFO_0000269

MYZAP
type: EnsemblDatabaseReference

RHOJ
type: EnsemblDatabaseReference

CEP55 DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.16090733333333
p value: 0.0103059894177363
refers to: CEP55
refers to: 218542_at
t statistic: -5.1402717871072

SLC4A3
type: EnsemblDatabaseReference

Homo sapiens
type: OBI_0100026

C7 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.51561023333333
p value: 0.0128425207028045
refers to: C7
refers to: 202992_at
t statistic: -5.13517471961401

MYZAP DOWN in 'Tmprss6 wild type' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4398002
p value: 0.00648448164425075
refers to: MYZAP
refers to: 228568_at
t statistic: -6.12829204964623

EDN1
type: EnsemblDatabaseReference

AGR2 UP in 'Tmprss6 mutant' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 2.273121
p value: 0.00626993896578657
refers to: 209173_at
refers to: AGR2
t statistic: 9.30656314729228

208763_s_at
type: EFO_0005072
part of: A-AFFY-44

EDN1 UP in 'Tmprss6 wild type' vs 'empty vector'
type: IncreasedDifferentialExpressionRatio
fold change: 1.11806946666667
p value: 8.97786660528121E-4
refers to: EDN1
refers to: 222802_at
t statistic: 10.8491671146114

CYP3A5
type: EnsemblDatabaseReference

SYNE1
type: EnsemblDatabaseReference

SLC5A3 DOWN in 'Tmprss6 mutant' vs 'empty vector'
type: DecreasedDifferentialExpressionRatio
fold change: -1.45072436666667
p value: 0.0106147930931836
refers to: 1553313_s_at
refers to: SLC5A3
t statistic: -6.57052928134323

CDR2L
type: EnsemblDatabaseReference

AREG
type: EnsemblDatabaseReference