(Assay) Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep4
has participant: A-AFFY-6

Lum
type: EnsemblDatabaseReference

Gbp5
type: EnsemblDatabaseReference

Gas6 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13641128219445
p value: 0.0270432845905203
refers to: 99067_at
refers to: Gas6
t statistic: -4.32178208212977

97819_at
type: EFO_0005072
part of: A-AFFY-6

Gas2
type: EnsemblDatabaseReference

Rhou UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.04534209172234
p value: 0.015624996437376
refers to: 96747_at
refers to: Rhou
t statistic: 5.04689945165689

Ptgis
type: EnsemblDatabaseReference

Chd3os UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.02859096815732
p value: 0.00773421348384312
refers to: Chd3os
refers to: 160905_s_at
t statistic: 6.21235322729945

(Sample) genotype/Irs gene knockout
type: EFO_0000001
property type: genotype
property value: Irs gene knockout

95974_at
type: EFO_0005072
part of: A-AFFY-6

99010_at
type: EFO_0005072
part of: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT2_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_WT2_IGF1_0min_rep3
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT3_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_WT3_IGF1_0min_rep3
has participant: A-AFFY-6

93503_at
type: EFO_0005072
part of: A-AFFY-6

Enpp2
type: EnsemblDatabaseReference

94345_at
type: EFO_0005072
part of: A-AFFY-6

160319_at
type: EFO_0005072
part of: A-AFFY-6

Efnb2
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_WT2_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_WT2_IGF1_0min_rep2
has participant: A-AFFY-6

Plac8
type: EnsemblDatabaseReference

Gsto1 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.08997745781453
p value: 0.00309402521465168
refers to: Gsto1
refers to: 97819_at
t statistic: 9.4329790749177

Calml4
type: EnsemblDatabaseReference

Rspo2 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.40695470490108
p value: 0.00617676731698627
refers to: Rspo2
refers to: 93375_at
t statistic: -6.97529930411938

Col8a1 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.36562554160699
p value: 0.0057658998551914
refers to: 100308_at
refers to: Col8a1
t statistic: 7.19068198935168

Zic1
type: EnsemblDatabaseReference

Art3 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.4985983325108
p value: 0.0266372715089345
refers to: Art3
refers to: 98924_at
t statistic: -4.34473400814047

(Assay) Hybridization: m_C-preBAT_WT1_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_WT1_IGF1_0min_rep1
has participant: A-AFFY-6

104169_at
type: EFO_0005072
part of: A-AFFY-6

Plac8
type: EnsemblDatabaseReference

Rspo2
type: EnsemblDatabaseReference

Gpm6b DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04117906777451
p value: 0.00143115839715543
refers to: Gpm6b
refers to: 99178_at
t statistic: -12.1988686584419

(Assay) Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep2
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT3_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_WT3_IGF1_0min_rep2
has participant: A-AFFY-6

Cdkn1c
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep2
has participant: A-AFFY-6

Gas2 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.66698645846457
p value: 0.00303804905538931
refers to: Gas2
refers to: 94338_g_at
t statistic: -9.72737107210656

Capn6
type: EnsemblDatabaseReference

Gpm6b
type: EnsemblDatabaseReference

Col8a1
type: EnsemblDatabaseReference

Sfrp2
type: EnsemblDatabaseReference

Il6st DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.00160963523456
p value: 0.00143115839715543
refers to: Il6st
refers to: 94345_at
t statistic: -11.480361356581

Rhou
type: EnsemblDatabaseReference

Islr DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.15302856782001
p value: 0.00490695274670969
refers to: Islr
refers to: 99010_at
t statistic: -8.00202442830744

(Assay) Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep1
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep3
has participant: A-AFFY-6

Ndn
type: EnsemblDatabaseReference

Sfrp2
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep4
has participant: A-AFFY-6

Ptgis
type: EnsemblDatabaseReference

Mus musculus
type: OBI_0100026

(Assay) Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_IRS4-KO_IGF1_0min_rep1
has participant: A-AFFY-6

99178_at
type: EFO_0005072
part of: A-AFFY-6

A-AFFY-6
type: EFO_0000269

104538_at
type: EFO_0005072
part of: A-AFFY-6

Lum DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.13304644290238
p value: 0.0188651551424825
refers to: 93353_at
refers to: Lum
t statistic: -4.81014004021546

(Sample) genotype/wild type genotype
type: EFO_0000001
property type: genotype
property value: wild type genotype

(Factor value) GENOTYPE/Irs gene knockout
type: EFO_0000001
property type: GENOTYPE
property value: Irs gene knockout

Enpp2
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_WT1_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_WT1_IGF1_0min_rep3
has participant: A-AFFY-6

Myl1
type: EnsemblDatabaseReference

99067_at
type: EFO_0005072
part of: A-AFFY-6

Zic1 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 2.51110751563801
p value: 0.0239709921253084
refers to: Zic1
refers to: 104169_at
t statistic: 4.51731842800312

Islr
type: EnsemblDatabaseReference

Efnb2
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep2
has participant: A-AFFY-6

Art3
type: EnsemblDatabaseReference

94338_g_at
type: EFO_0005072
part of: A-AFFY-6

Sfrp2 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.55015184555738
p value: 0.0121434714386931
refers to: Sfrp2
refers to: 93503_at
t statistic: -5.44769004331496

Il1rn
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep3
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT2_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_WT2_IGF1_0min_rep4
has participant: A-AFFY-6

Calml4
type: EnsemblDatabaseReference

93871_at
type: EFO_0005072
part of: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT1_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_WT1_IGF1_0min_rep2
has participant: A-AFFY-6

Enpp2 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.05959229905583
p value: 0.0397053738373918
refers to: Enpp2
refers to: 97317_at
t statistic: -3.8392975155215

(Assay) Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep3
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_WT2_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_WT2_IGF1_0min_rep1
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep1
has participant: A-AFFY-6

160905_s_at
type: EFO_0005072
part of: A-AFFY-6

Capn6
type: EnsemblDatabaseReference

Lpl
type: EnsemblDatabaseReference

Il6st
type: EnsemblDatabaseReference

Gsto1
type: EnsemblDatabaseReference

Col8a1
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_WT3_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_WT3_IGF1_0min_rep1
has participant: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep3
type: Assay
identifier: Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep3
has participant: A-AFFY-6

Ptgis UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.40642373910671
p value: 0.00490695274670969
refers to: 104538_at
refers to: Ptgis
t statistic: 7.90741980800886

Sparcl1 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.47656001900171
p value: 0.00143115839715543
refers to: Sparcl1
refers to: 160319_at
t statistic: -11.7046200136818

Rhou
type: EnsemblDatabaseReference

Calml4 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04329846044476
p value: 0.0119285873007197
refers to: Calml4
refers to: 96203_at
t statistic: -5.49345709688585

Lpl
type: EnsemblDatabaseReference

98092_at
type: EFO_0005072
part of: A-AFFY-6

(Sample) cell type/preadipocyte
type: CL_0002334
property type: cell type
property value: preadipocyte

(Assay) Hybridization: m_C-preBAT_WT1_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_WT1_IGF1_0min_rep4
has participant: A-AFFY-6

Ndn
type: EnsemblDatabaseReference

Gas6
type: EnsemblDatabaseReference

(Sample) organism/Mus musculus
type: Mus musculus
property type: organism
property value: Mus musculus

Lum
type: EnsemblDatabaseReference

Gbp5
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep1
type: Assay
identifier: Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep1
has participant: A-AFFY-6

Gas2
type: EnsemblDatabaseReference

Myl1
type: EnsemblDatabaseReference

160083_at
type: EFO_0005072
part of: A-AFFY-6

(Factor value) GENOTYPE/wild type genotype
type: EFO_0000001
property type: GENOTYPE
property value: wild type genotype

Islr
type: EnsemblDatabaseReference

Art3
type: EnsemblDatabaseReference

(Assay) Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep2
type: Assay
identifier: Hybridization: m_C-preBAT_IRS1-KO_IGF1_0min_rep2
has participant: A-AFFY-6

96203_at
type: EFO_0005072
part of: A-AFFY-6

Gbp5 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.03641430718221
p value: 0.0258534991989753
refers to: Gbp5
refers to: 95974_at
t statistic: 4.4125355079981

97942_g_at
type: EFO_0005072
part of: A-AFFY-6

Analysis of 'Irs gene knockout' vs 'wild type genotype'
type: MicroarrayDifferentialExpressionAnalysis

Lpl DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.55628347224513
p value: 0.0119285873007197
refers to: 160083_at
refers to: Lpl
t statistic: -5.52737848264788

93375_at
type: EFO_0005072
part of: A-AFFY-6

Il1rn
type: EnsemblDatabaseReference

Capn6 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.1826137731363
p value: 0.00520694339047371
refers to: Capn6
refers to: 97942_g_at
t statistic: -7.64347218835185

Ndn UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.77469714110538
p value: 0.00660704874128317
refers to: 101059_at
refers to: Ndn
t statistic: 6.74295143581562

92541_at
type: EFO_0005072
part of: A-AFFY-6

Efnb2 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.15274064968569
p value: 0.00848535717869326
refers to: Efnb2
refers to: 160857_at
t statistic: 6.07319550041069

(Assay) Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_IRS3-KO_IGF1_0min_rep4
has participant: A-AFFY-6

Sparcl1
type: EnsemblDatabaseReference

Plac8 UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.33893867699317
p value: 0.0325501955789772
refers to: Plac8
refers to: 98092_at
t statistic: 4.0746970776735

93353_at
type: EFO_0005072
part of: A-AFFY-6

(Assay) Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_IRS2-KO_IGF1_0min_rep4
has participant: A-AFFY-6

100308_at
type: EFO_0005072
part of: A-AFFY-6

95471_at
type: EFO_0005072
part of: A-AFFY-6

Il1rn DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.04227235964418
p value: 0.0494745067752617
refers to: Il1rn
refers to: 93871_at
t statistic: -3.57367320646193

101059_at
type: EFO_0005072
part of: A-AFFY-6

Sparcl1
type: EnsemblDatabaseReference

Il6st
type: EnsemblDatabaseReference

Gsto1
type: EnsemblDatabaseReference

Zic1
type: EnsemblDatabaseReference

E-CBIL-26
type: microarray 1colour mrna differential
RO_0002162: Mus musculus
description: Brown preadipocytes were grown to confluence and synchronized by overnight serum starvation. Four independent RNA samples were analyzed from each IRS KO cell line and three independent clones of WT cells were separately analyzed as controls. Splitting of the samples resulted in a total 28 microarrays. 15 mg of adjusted cRNA were hybridized to Affymetrix U74A-v2 arrays.
uses data from: http://identifiers.org/pubmed/15895078

Rspo2
type: EnsemblDatabaseReference

Chd3os
type: EnsemblDatabaseReference

96747_at
type: EFO_0005072
part of: A-AFFY-6

Cdkn1c
type: EnsemblDatabaseReference

Gas6
type: EnsemblDatabaseReference

98924_at
type: EFO_0005072
part of: A-AFFY-6

Myl1 DOWN in 'Irs gene knockout' vs 'wild type genotype'
type: DecreasedDifferentialExpressionRatio
fold change: -1.36600033808578
p value: 0.0349644313737257
refers to: 92541_at
refers to: Myl1
t statistic: -3.99063467456823

(Assay) Hybridization: m_C-preBAT_WT3_IGF1_0min_rep4
type: Assay
identifier: Hybridization: m_C-preBAT_WT3_IGF1_0min_rep4
has participant: A-AFFY-6

160857_at
type: EFO_0005072
part of: A-AFFY-6

Gpm6b
type: EnsemblDatabaseReference

Chd3os
type: EnsemblDatabaseReference

97317_at
type: EFO_0005072
part of: A-AFFY-6

Cdkn1c UP in 'Irs gene knockout' vs 'wild type genotype'
type: IncreasedDifferentialExpressionRatio
fold change: 1.4787044059993
p value: 0.0324923809687581
refers to: Cdkn1c
refers to: 95471_at
t statistic: 4.08050203370213